| Project/Area Number |
15500485
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
INAMIZU Tsutomu Hiroshima University, Graduate School of Health Sciences, Professor, 大学院・保健学研究科, 教授 (00112186)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2004: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2003: ¥2,200,000 (Direct Cost: ¥2,200,000)
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| Keywords | salivary sIgA / salivary lysozyme / local immunity / upper respiratory tract infection / physical condition / exercise / コンディショニング |
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| Research Abstract |
The upper respiratory tract infection(URTI) is a maximal factor to deteriorate physical condition in athletes, and decreases or deficiencies in salivary secretory immunoglobulin A(sIgA) or salivary lysozyme are associated with URTI. The aim of this study was to investigate the influences of exercise on salivary sIgA and salivary lysozyme, and the relationships between URTI and these immunological substances, and to establish the way to maintain good physical condition by monitoring salivary sIgA and lysozyme.
Results are as follows.
1)The salivary sIgA concentration and secretion rate increased significantly after acute exercise at 60% VO2max intensity level (P<0.05).
2)The salivary lysozyme concentration and secretion rate increased significantly after acute exercise at 80%, 60% and 40% VO2max intensity levels (P<0.05).
3)Over the 8-week training program, there were no significant increases in concentration and secretion rate of salivary both sIgA and lysozyme (P>0.05).
4)The salivary sIgA concentration and secretion rate of subjects with URTI were significantly lower than that of non-infected subjects (P<0.01).
5)The salivary lysozyme concentration and secretion rate of subjects with URTI were significantly lower than that of non-infected subjects (p<0.001).
6)The sIgA concentration below 85μg/ml and lysozyme cncentration below 3.5μg/ml are the dangerous levels of URTI affection.
7)The monitoring of salivary sIgA and lysozyme concentration could foresee danger of URTI, and it is useful for health care and making of good physical condition of both in athletes and in general community.
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