| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,600,000)
Fiscal Year 2006: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2005: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2004: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2003: ¥700,000 (Direct Cost: ¥700,000)
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| Research Abstract |
Objective : The purpose of the study is to examine effects of the nutritional improvement resulting from a four-year community-directed intervention on the risk of all-cause mortality in the functionally competent community-living senior citizens. Design : a ten-year follow-up study. Setting and methods : The study population was a representative sample of functionally competent seniors aged≧65 years (243 men, 386 women, mean age : 71.0 years) living in a rural area (Nangai village, Northern Japan). The population showed a significant increase of albumin level (4.11g/dL → 4.27g/dL) resulting from a four-year nutritional intervention (from 1996 to 2000). The population was divided into three-group based on level of change in albumin (t alb) over the intervention period ; Group 1 : 0.0g/dL (25 percentile) ≦ Δalb, Group2 ; 0.0g/dL < Δalb < +0.3g/dL (75 percentile), Group3 ; +0.3g/dL ≦ Δalb. Risks of all-cause mortality of the three groups over the 6-year (from 2000 to 2006) of the post-intervention was assessed, using the Cox proportional hazard model. Results : Over the 6-year of follow-up, 88(14.0%) men and women died. The risk of all-cause mortality was inversely associated with increase level of albumin over the intervention period, The multivariate hazard ratios were 1.00 (reference) for group1, 0.69 (95% confidence interval [CI], 0.42-1.12) for group2, 0.47 (0.24-0.90) for group3, adjusting for sex, age, albumin level at 1996 year, high-level functional capacity at 2000 year, exercise habits, stroke, heart disease, diabetes, smoking, drinking. Conclusions : The results suggested that intervention for enhancing nutritional status reduced the risk of all cause mortality in the functionally competent community-living senior citizens. The intervention of nutritional enhancement may postpone aging in the elderly
people.
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