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Diversity of mycotic zoonoses and the elucidation of the clinical symptom

Research Project

Project/Area Number 15580282
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied veterinary science
Research InstitutionNational Institute of Health Sciences

Principal Investigator

TAKATORI Kosuke  National Institute of Health Sciences, Division of Microbiology, Director, 衛生微生物部, 部長 (50270624)

Co-Investigator(Kenkyū-buntansha) AIHARA Maki  National Institute of Health Sciences, Division of Microbiology, Researcher, 衛生微生物部, 研究員 (30373393)
Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2004: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2003: ¥2,400,000 (Direct Cost: ¥2,400,000)
Keywordszoonoses / dwelling environment / diversification / infectious agent / dispersal / pathogenic fungi / dermatophytosis / host-parasite specificity / 輸入真菌症 / 日和見感染 / 深在性真菌症 / 皮膚糸状菌 / 病原性因子
Research Abstract

Mycotic zoonoses caused by opportunistic fungi in dwelling ace seriously important problem as well as public health. Therefore, the authors were investigated on the mycology, ecology, epidemiology and clinical pathology of mycotic zoonoses. The diversity of mycotic zoonoses caused by pathogens was extremely progressing. Especially the investigation in this work was carried out the previous results which reported in other papers. The results were showed as followings ;
(1)Fungal distribution in dwellings : The fungi were mainly distributed in Mucorales as Rhizopus, Absidia, Mucor, Martierella, dematious hyphomycetes as Exophiala, Aureobasidium around wet environments as like bath room, lavatory kitchen. Emericelh was isolated from dusts, Tatami and close which was somewhat dry area. Candida was isolated from human and animal surface or mucous membrane, and also isolated from clothes-changing room and bath room.
(2)The diversity of mycotic zoonoses : With the pet clinics, the authors were sampling with the specimens from the disorderand isolated from the pathogens. The main mycotic diseases were dermatophytoses in this country and the following diseases were Aspergillosis, Zygomycoses, Fusariosis, Candidiosis and Cryptococcosis. The opportunistic pathogens were gradually increasing in dwelling environments like as the interurban buildings rather than rural areas.
(3)The biological and epidemiological studies in the pathogens : The pathogens had a biological activities like the producibility of extracellular metabolites in which included proteolytic enzyme. The high proteolytic activities were showed by Emericella nidulans, Aspergillus fumigatus, A.terreus and Scopulariopsis. Furthermore, the zygomycetes, Scedosporium, Emericella and Aspergillus fumigatus showed the hemolytic activities.
This investigation on the mycotic zoonoses and epidemiological surveillance apparently suggested the available information in public health and also dwelling environments.

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (56 results)

All 2005 2004 2003 Other

All Journal Article (40 results) Book (6 results) Publications (10 results)

  • [Journal Article] Subcutaneous granuloma associated with Macrophomia species infection in a cat2005

    • Author(s)
      T.Hasegawa et al.
    • Journal Title

      The Veterinary Record 156

      Pages: 23-24

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Subcutaneous granuloma associated with Macrophomia species infection in a cat2005

    • Author(s)
      Hasegawa T. et al.
    • Journal Title

      The Veterinary Record 156

      Pages: 23-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Computer-Assisted Image Processing Techniques for Quantitative Analysis of Cell Migrations on Collagen-Coated Grass2005

    • Author(s)
      B.J.Park, S.C.Kim, D.H.Lee, H.J.Son, K.C.Nam, K.Takatori, M.Aihara, J.-C.Park
    • Journal Title

      Key Engineering Materials 288-289

      Pages: 503-506

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The Influences of β-Glucan Associated with BMP-7 on MC3T3-E1 Proliferation and Osteogenic Differentiation2005

    • Author(s)
      D.H.Lee, D.-W.Han, B.J.Park, H.S.Baek, K.Takatori, M.Aihara, K.Tsubaki, J.-C.Park
    • Journal Title

      Key Engineering Materials 288-289

      Pages: 241-244

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Subcutaneous granuloma associated with Macrophomia species infection in a cat2005

    • Author(s)
      T.Hasegawa, Y.Yoshida, J.Kosuge, T.Haga, Y.Goto, T.Shinjo, K.Uchida, R.Yamaguchi, S.Takeyama, K.Takatori
    • Journal Title

      The Veterinary Recoad 156

      Pages: 23-24

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 質疑応答Q & A 食品に付着した真菌の神経毒と病状・病態2005

    • Author(s)
      高鳥浩介
    • Journal Title

      日本医事新報 4219

      Pages: 111-112

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 獣医師として幅広い研究活動に期待-時代の流れに任せることなく-2005

    • Author(s)
      高鳥浩介
    • Journal Title

      日獣会誌 58・3

      Pages: 139-142

    • NAID

      10015433043

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 病原性真菌の今日的意味(10) 4.真菌とアレルギー2004

    • Author(s)
      高鳥浩介ら
    • Journal Title

      化学療法の領域 20

      Pages: 351-355

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Fungal sterilization using microwave-induced argon plasma at atmospheric pressure2004

    • Author(s)
      Jong Chul Park et al.
    • Journal Title

      Journal of Microbiology and Biotechnology 14

      Pages: 188-192

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Untersuchung des Einflusses von Licht auf die Entwicklung von Schimmelpilzen2004

    • Author(s)
      Tatsuaki Tanaka et al.
    • Journal Title

      Gesund-Ingenieur-Haustechnik-Bauphysik-Umwelttechnik 125

      Pages: 142-145

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 室内環境とカビ2004

    • Author(s)
      高鳥浩介ら
    • Journal Title

      静電気学会誌 28

      Pages: 167-170

    • NAID

      10013079972

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Survey of fungal contamination in ordinary houses in Japan2004

    • Author(s)
      Ara Katsutosi et al.
    • Journal Title

      Allergology International 53

      Pages: 369-377

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 大気中の感染性微生物とバイオセーフティ管理2004

    • Author(s)
      小菅旬子ら
    • Journal Title

      空気調和・衛生工学 78

      Pages: 335-340

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Fungi and fungal allergy2004

    • Author(s)
      Takatori K. et al.
    • Journal Title

      Antibiotics & Chemotherapy 20

      Pages: 351-355

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Fungal sterilization using microwave-induced argon plasma at atmospheric pressure2004

    • Author(s)
      Park J.C.et al.
    • Journal Title

      Journal of Microbiology and Biotechnology 14

      Pages: 188-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Untersuchung des Einflusses von Licht auf die Entwicklung von Schimmelpilzen2004

    • Author(s)
      Tanaka T. et al.
    • Journal Title

      Gesund-Ingenieur-Haustechnik -Bauphysik-Umwelttec hnik 125

      Pages: 142-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Indoor environment and fungi2004

    • Author(s)
      Takatori K. et al.
    • Journal Title

      Journal of the Institute of Electrostatics Japan 28

      Pages: 167-170

    • NAID

      10013079972

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Survey of fungal contamination in ordinary houses in Japan2004

    • Author(s)
      Ara K.et al.
    • Journal Title

      Allergology International 53

      Pages: 369-377

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] The infectious microbes in the air and biosafety control2004

    • Author(s)
      Kosuge J. et al.
    • Journal Title

      Heating, Air-Conditioning and Sanitary Engineers 78

      Pages: 335-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Inactivation of Vibrio parahaemoliticus in effluent seawater by alternating current treatment2004

    • Author(s)
      Jong Chul Park, Min Sub Lee, Dong Hee Lee, Bong Joo Park, In-Seop Lee, M.Uzawa, Maki Aihara, Kosuke Takatori
    • Journal Title

      Appi.Environment.Microbiol. 70

      Pages: 1833-1835

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Fungal sterilization using microwave-induced argon plasma at atmospheric pressure2004

    • Author(s)
      Jong Chul Park, Bong Joo Park, Dong Hee Lee, In-Seop Lee, Moon Sung Chun, Maki Aihara, Kosuke Takatori
    • Journal Title

      J.Microbiol.Biotechnol. 14・1

      Pages: 188-192

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 腸管出血性大腸菌O157:H打7犬腸管内における挙動2004

    • Author(s)
      楠博文, 笹井和美, 馬場栄一郎, 深田恒夫, 高鳥浩介, 植村興
    • Journal Title

      日本獣医師会雑誌 57・5

      Pages: 326-329

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Untersuchung des Einflusses von Licht auf die Entwicklung von Schimmelpilzen2004

    • Author(s)
      Tatsuaki Tanaka, Kosuke Takatori, Tomoe Doi
    • Journal Title

      Gesund-Ingenieur-Haustechnik-Bauphysik-Umwelttechnik 125

      Pages: 142-145

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 室内環境とカビ2004

    • Author(s)
      高鳥浩介, 相原真紀, 李憲俊
    • Journal Title

      静電気学会誌 28・3

      Pages: 167-170

    • NAID

      10013079972

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Survey of fungal contamination in ordinary houses in Japan2004

    • Author(s)
      Ara Katsutosi, M.Aihara, M.Ojima, Y.Toshima, C.Yabune, H.Tokuda, S.Kawai, N.Ueda, T.Tanaka, K.Akiyama, K.Takatori
    • Journal Title

      Allergology Intnatl. 53

      Pages: 369-377

    • NAID

      10014261407

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Propagation of a protease-resistant form of prion protein in long-term cultured human glioblastoma cell line T98G2004

    • Author(s)
      Yutaka Kikuti, Tomoshi Kakeya, Ayako Sakai, Kosuke Takatori, Naoto Nakamura, Haruko Matsuda, Takeshi Yamazaki, Ken-ichi Tanamoto, Jun-ichi Sawada
    • Journal Title

      J.General Virology 85

      Pages: 3449-3457

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 細菌・真菌の計測と安全評価-計測の必要性と安全性の理解のために-2004

    • Author(s)
      高鳥浩介, 相原真紀
    • Journal Title

      BE建築設備 55・2

      Pages: 34-40

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 病原性真菌の今日的意味 4.真菌とアレルギー2004

    • Author(s)
      高鳥浩介, 相原真紀
    • Journal Title

      化学療法の領域 20・3

      Pages: 351-355

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 大気中の感染性微生物とバイオセーフティ管理2004

    • Author(s)
      小菅旬子, 高鳥浩介
    • Journal Title

      空気調和・衛生工学 78・5

      Pages: 335-340

    • NAID

      10012933049

    • Related Report
      2004 Annual Research Report
  • [Journal Article] こんなにある食品のカビ-その正体と健康被害-2004

    • Author(s)
      高鳥浩介, 相原真紀
    • Journal Title

      食と健康 48・9

      Pages: 54-63

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 獣医領域からみた人獣共通真菌症の問題点2003

    • Author(s)
      高鳥浩介ら
    • Journal Title

      真菌誌 44

      Pages: 249-251

    • NAID

      50000000431

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Aspergillus restrictus - そのアレルゲンとしての意義2003

    • Author(s)
      谷口正実ら
    • Journal Title

      Allergy Update 15

      Pages: 8-9

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 住環境由来真菌の建築資材等基質への付着および初期発育2003

    • Author(s)
      土肥友恵ら
    • Journal Title

      防菌防黴 31

      Pages: 319-322

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 家庭環境と防菌防黴2003

    • Author(s)
      高鳥浩介ら
    • Journal Title

      防菌防黴 31

      Pages: 663-667

    • NAID

      50000319315

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 微生物汚染についての考え方2003

    • Author(s)
      高鳥浩介ら
    • Journal Title

      IBEC 24

      Pages: 5-9

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Some remarks on mycotic zoonoses from Veterinary Medicine2003

    • Author(s)
      Takatori K. et al.
    • Journal Title

      Japanese Journal of Medical Mycology 44

      Pages: 249-251

    • NAID

      50000000431

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Aspergillus restrictus2003

    • Author(s)
      Taniguchi M. et al.
    • Journal Title

      Allergy Update 15

      Pages: 8-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] The adhesion of fungi from the indoor environment to building materials and their early stage of growth2003

    • Author(s)
      Doi T.et al.
    • Journal Title

      Bokin Bobai 31

      Pages: 319-322

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Antibacterial and antifungal agents for home environment2003

    • Author(s)
      Takatori K. et al.
    • Journal Title

      Bokin Bobai 31

      Pages: 663-667

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] The point of view about microbiological contamination2003

    • Author(s)
      Takatori K. et al.
    • Journal Title

      IBEC 24

      Pages: 5-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] 獣医公衆衛生学(高島郁夫, 熊谷進編)2004

    • Author(s)
      高鳥浩介
    • Total Pages
      516
    • Publisher
      文永堂出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Book] 獣医疫学2004

    • Author(s)
      高鳥浩介
    • Total Pages
      231
    • Publisher
      近代出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Book] Veterinary public health, 3^<rd> ed.2004

    • Author(s)
      Takatori K.(edited by Takashima I.et al.)
    • Total Pages
      516
    • Publisher
      Buneido Publishing
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] Veterinary epidemiology2004

    • Author(s)
      Takatori K.(edited by Japan Society of Veterinary Epidemiology)
    • Total Pages
      231
    • Publisher
      Kindai Publishing
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] New Horizon of Mycotoxicology for Assuring Food Safety2004

    • Author(s)
      Toshitsugu TANAKA, Takumi YOSHIZAWA, Hiroki TANAKA, Yoshitsugu SUGIURA, Kosuke TAKATORI, Susumu KUMAGAI
    • Total Pages
      356
    • Publisher
      微功社
    • Related Report
      2004 Annual Research Report
  • [Book] 食品衛生検査指針 微生物編(厚生労働省監修)2004

    • Author(s)
      高鳥浩介
    • Total Pages
      705
    • Publisher
      (社)日本食品衛生協会
    • Related Report
      2004 Annual Research Report
  • [Publications] Ayako Sakai, Yutaka Kikuchi, Sasashi Muroi, Tohru Masui, Chie Furuhata, Eriko Uchida, Kosuke Takatori, Ken-ichi Tanamoto: "Overexpression of NP95 mRNA by tumor promotes in the promotion phase of a two-stage BALB/3T3 cell transformation assay"Biol.Pharm.Bull.. 26・3. 347-351 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 斎藤貞子, 前田直之, 和田正夫, 井上幸次, 光永サチ子, 濱野光, 高鳥浩介: "ソフトコンタクトレンズに増殖しする真菌の低真空走査型顕微鏡による観察"日コレ誌. 45. 28-32 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 谷口正実, 竹内保雄, 斎藤明美, 安枝浩二, 信太隆夫, 秋山一男, 高鳥浩介: "Aspergillus restrictusその抗原としての意義"Allergy Update. 15・1. 8-9 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 土肥友恵, 田中辰明, 李憲俊, 相原真紀, 高鳥浩介: "住環境由来真菌の建築資材等基質への付着および初期発育"防菌防黴. 31・6. 319-322 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Jong Chul Park.Min Sub Lee, Dong Hee Lee, Bong Joo Park, Dong Wook Han, Masakazu Uzawa, Kosuke Takatori: "Inactivation of bacteria in seawater by low-amperage electric current"Appl.Environment.Microbiol.. 69・4. 2405-2408 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高鳥浩介, 小菅旬子: "獣医領域からみた人獣共通真菌症の問題点"真菌誌. 44. 249-251 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高鳥浩介, 相原真紀: "家庭環境と防菌防黴"防菌防黴. 31. 663-667 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高鳥浩介, 相原真紀, 村松芳多子: "微生物汚染についての考え方"IBEC. 24. 5-9 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高鳥浩介, 相原真紀: "細菌・真菌の計測と安全性評価-計測の必要性と安全性の理解のために-"BE建築設備. 55・2. 34-40 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高鳥浩介, 相原真紀: "病原性真菌の今日的意味 4.真菌とアレルギー"化学療法の領域. 20・3. 351-355 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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