• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Research on Psychosocial and Ethical Aspects of Living Donor Liver Transplantation

Research Project

Project/Area Number 15590456
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical sociology
Research InstitutionThe University of Tokyo

Principal Investigator

AKABAYASHI Akira  The University of Tokyo, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 (70221710)

Co-Investigator(Kenkyū-buntansha) KODAMA Satoshi  The University of Tokyo, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手 (80372366)
田中 紘一  京都大学, 大学院・医学研究科, 教授 (20115877)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2005: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2004: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2003: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsorgan transplantation / living donor liver transplantation / psychosocial aspects / qualitative study / professional ethics / biomedical ethics / informed consent
Research Abstract

Shortage of organs and advance of transplantation techniques have drawn international attention to living donor liver transplantation (LDLT), especially adult-to-adult right lobe hepatectomy. This study aims to construct a decision-making model of the psychological process leading up to donation in adult LDLT for a donor.
Twenty-two donors (15 males and 7 females, an average age of 37.9±10.1 (SD)) were interviewed using a semi-structured format. Questions included how participants felt when they first learned of the need for transplantation, circumstances of conversation (s) with family about who should be the donor, and so forth. Interviews were conducted after the operation (mean 12.6±5.2 days), lasted 48 minutes on average and ranged in duration from 20 to 77 minutes. All interviews were tape-recorded, transcribed verbatim, and analyzed based on grounded theory.
A decision-making model was developed consisting of five-stages : (1) recognition, (2) digestion, (3) decision-making, (4) reinforcement, and (5) resolution. The second and the third stages described donors' experiences of "reaching a decision;" the latter two described that of "facing transplantation." The central theme of this model was "having no choice," which consisted of four codes : (1) priority of life, (2) only LDLT, (3) for family, and (4) only me. Although the reality of having no choice existed as a psychological burden, it concurrently motivated each participant to donate throughout the process.
The model of "having no choice" describes the psychological process of donors' decision-making in LDLT. This study's framework serves as an essential tool for healthcare professionals to understand a donor's experience and, based on that understanding, to provide sufficient support to the donor.

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (24 results)

All 2006 2005 2004 2003 Other

All Journal Article (18 results) Book (1 results) Publications (5 results)

  • [Journal Article] A model of donors' decision-making in adult-to-adult living donor liver transplantation in Japan : having no choice2006

    • Author(s)
      Fujita, M, Akabayashi A, Slingsby, BT, Kosugi, S, Fujimoto, Y, Tanaka,K.
    • Journal Title

      Liver Transplantation 12

      Pages: 768-774

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A model of donors' decision-making in adult-to-adult living donor liver transplantation in Japan : having no choice2006

    • Author(s)
      Fujita, M, Akabayashi, A, Slingsby, BT, Kosugi, S, Fujimoto, Y, Tanaka, K.
    • Journal Title

      Liver Transplantation 12

      Pages: 768-774

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A model of donors' decision-making in adult-to-adult living donor liver transplantation in Japan : having no choice2006

    • Author(s)
      Fujita, M, Akabayashi A, Slingsby, BT, Kosugi, S, Fujimoto, Y, Tanaka, K.
    • Journal Title

      Lever Transplantation (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Live organ-donation for islet transplantation2005

    • Author(s)
      Slingsby, BT, Akabayashi A.
    • Journal Title

      Lancet 366(9479)

      Pages: 26-27

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Conflict of interest : a Japanese perspective2005

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      Cambridge Quarterly of Healthcare Ethics 14(3)

      Pages: 277-280

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Live organ-donation for islet transplantation2005

    • Author(s)
      Slingsby, BT, Akabayashi, A. et al.
    • Journal Title

      Lancet 366(9479)

      Pages: 26-27

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The first donor death after living-related liver transplantation in Japan2004

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      Transplantation 77(4)

      Pages: 634-634

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Three patterns of voluntary consent in the case of adult to adult living related liver transplantation in Japan2004

    • Author(s)
      Fujita, M, Slingsby, BT, Akabayashi, A.
    • Journal Title

      Transplantation Proceedings 36(5)

      Pages: 1425-1428

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Administrative legislation in Japan : guidelines on scientific and ethical standards2004

    • Author(s)
      Slingsby, BT, Nagao, N, Akabayashi, A.
    • Journal Title

      Cambridge Quarterly of Healthcare Ethics 13(3)

      Pages: 245-253

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Administrative legislation in Japan : guidelines on scientific and ethical standards2004

    • Author(s)
      Slingsby, BT, Nagao, Akabayashi, A. et al.
    • Journal Title

      Cambridge Quarterly of Healthcare Ethics 13(3)

      Pages: 245-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Three patterns of voluntary consent in the case of adult to adult living related liver transplantation in Japan2004

    • Author(s)
      Fujita, M, Slingsby, BT, Akabayashi, A. et al.
    • Journal Title

      Transplantation Proceedings 36(5)

      Pages: 1425-1428

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The development of a brief and objective method for evaluating moral sensitivity and reasoning in medical students.2004

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      BMC Medical Ethics 5:1

      Pages: 1-7

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The first donor death after living-related liver transplantation in Japan.2004

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      Transplantation 77

      Pages: 634-634

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Administrative legislation in Japan : guidelines on scientific and ethical standards.2004

    • Author(s)
      Slingsby, B.T., Nagao, N., Akabayashi, A.
    • Journal Title

      Cambridge Quarterly of Healthcare Ethics. 13

      Pages: 245-253

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Three patterns of voluntary consent in the case of adult to adult living related liver transplantation in Japan.2004

    • Author(s)
      Fujita, M., Slingsby, B.T., Akabayashi, A.
    • Journal Title

      Transplantation Proceedings 36

      Pages: 1425-1428

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 倫理委員会の機能と社会的責任についての論考:生体部分膵からの膵島移植を例として2004

    • Author(s)
      赤林 朗
    • Journal Title

      生命倫理 15(1)

      Pages: 100-106

    • NAID

      110006457533

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Biomedical ethics in Japan : the second stage2003

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      Cambridge Quarterly of Healthcare Ethics 12(3)

      Pages: 261-264

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Living related liver transplantation2003

    • Author(s)
      Akabayashi, A. et al.
    • Journal Title

      Gut 52(1)

      Pages: 152-152

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 入門・医療倫理I2005

    • Author(s)
      赤林 朗(編)
    • Total Pages
      358
    • Publisher
      けい草書房
    • Related Report
      2005 Annual Research Report
  • [Publications] Akabayashi, A. et al.: "Biomedical Ethics in Japan : The second stage"Cambridge Quarterly of Healthcare Ethics. 12(3). 261-264 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Akabayasyi, A. et al.: "Perspectives on advance directive in Japanese society."BMC Medical Ethics. 4:5. (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Akabayasyi, A. et al.: "Living related liver transplantation"Gut. 52(1). 152 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藤田みさお, 赤林 朗: "ストレス研究と倫理"ストレス科学. 18(1). 1-8 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 木村利人(編集主幹), 赤林朗(編集): "バイオエシックス・ハンドブック"法研. 462 (2003)

    • Related Report
      2003 Annual Research Report

URL: 

Published: 2003-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi