| Project/Area Number |
15590480
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
NISHIBORI Masahiro Tokyo Medical and Dental University, Faculty of Mediceine, Assistant, 医学部附属病院, 助手 (60189305)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Hiroshi Tokyo Medical and Dental University, Graduate School, Professor, 大学院・疾患生命研究部, 教授 (60155158)
MIOYAKE Yoichi Chiba University, Research Center for Frontier Medical Engineering, Professor, 工学部, 教授 (70027895)
TSUMURA Norimichi Chiba University, Faculty of Engineering, Associate Professor, 工学部, 助教授 (00272344)
TANAKA Naofumi Tokyo Medical and Dental University, Faculty of Medicine, Assistant, 医学部附属病院, 助手 (90280982)
MIYAZAKI Yasuhiro Tokyo Medical and Dental University, Graduate School, Assistant, 大学院・医歯学総合研究科, 助手 (40302848)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2004: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2003: ¥2,600,000 (Direct Cost: ¥2,600,000)
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| Keywords | spectral reflectance / spectral estimation / color reproduction / real color picture / medical imaging / estimation of pigmnt distribution / multispectral imaging / device-illuminant independence |
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| Research Abstract |
A system of illuminant-independent color reproduction has been developed for practical use in medicine, and its performance was subjectively evaluated by a group of healthcare professionals of various specialties. For medical diagnosis, it is important to archive image data of diseased skin for the purpose of visually reviewing its chronological changes. However, sufficient color reproduction quality has never developed for this purpose. First, the illuminant conditions at various locations in a university hospital were measured and it was found that illuminants used in the hospital have a wide range of colors and that some of them have color rendering index (Ra) values that are too low for ordinary colorimetric color reproduction. Therefore, the multi-spectral imaging technique was applied for the illuminant-independent color reproduction to correct the color adaptively to the various kinds of illuminant. The healthcare professionals group evaluated the reproduced skin color by comparing the images with real skin. The results verify the effectiveness of the developed system and also expose the medical need for shading reproduction in addition to averaged color reproduction.
After that, a prototype system was developed. That system translates color of skin captured by an ordinary three band camera to that of an actual one regardless of the illuminating conditions and simultaneously visualizes distribution of melanin, hemoglobin and oxyhemoglobin in real time. It will be expected to inspire a wide range of research activities for medical application.
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