| Project/Area Number |
15590597
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Gifu University |
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Principal Investigator |
AKAO Seigou Gifu University, Graduate School of Medicine, Associate Professor, 大学院・医学研究科, 助教授 (70248037)
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| Co-Investigator(Kenkyū-buntansha) |
FUJIWARA Hisayoshi Gifu University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授 (80115930)
ONO Takamasa Gifu University, Graduate School of Medicine, Research Associate, 大学院・医学研究科, 助手 (80345777)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2004: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2003: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | stimulation of acupuncture needle / mouse immunized against type II collagen / 関節リウマチモデル動物 / タイプIIコラーゲン誘導関節炎(CIA) / pXトランスジェニックマウス / 針治療 / 抗炎症作用 / CIAモデルマウス / ハリ刺激 |
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| Research Abstract |
We formed a hypothesis that the stimuli of acupuncture needle control arthritis of mouse. Arthritis model was made by immunizing mouse against type II collagen. Stimulation of acupuncture needle for 5 minutes to arthritis of mouse limbs was done every other day for a week. And we have studied next 5 items. 1. degree of arthritis 2. measurement of antigen against type II collagen 3. measurement of T cell and B cell 4. measurement of CD4 cell and CD8 cell 5. pathological findings of arthritis
But, we have had no meaningful evidence that stimuli of acupuncture needle control arthritis of mouse.
So we gave up our hypothesis.
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