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A basic research on development of a CAD system for multi-diseases in 3-D CT images

Research Project

Project/Area Number 15591263
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionGifu University

Principal Investigator

FUJITA Hiroshi  Gifu University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授 (10124033)

Co-Investigator(Kenkyū-buntansha) HOSHI Hiroaki  Gifu University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授 (60128395)
HARA Takeshi  Gifu University, Graduate School of Medicine, Associate Professor, 大学院・医学研究科, 助教授 (10283285)
ZHOU Xiangrong  Gifu University, Graduate School of Medicine, Research Associate, 大学院・医学研究科, 助手 (00359738)
NISHIHARA Sadamitsu  Hiroshima Prefectural College of Health Sciences, Research Associate, 保健福祉学部, 助手 (40290548)
ISHIGAKI Takeo  Nagoya University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授 (60094356)
後藤 裕夫  岐阜大学, 医学部, 助教授 (80144012)
Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2004: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2003: ¥1,700,000 (Direct Cost: ¥1,700,000)
KeywordsComputer-aided diagnosis / Medical image processing / Medical image recognition / CT / Computer-aided detection / International information exchange (USA)
Research Abstract

The aim of this study is to perform a basic research on developing a computer-aided diagnosis (CAD) system for multi-diseases, especially existing in thoracic and abdominal regions, in 3-dimentional (3D) multi-slice CT images and to investigate its applicability to clinical situations. We have obtained the results as shown below.
1)Collection of 3D X-ray CT images (construction of CT image database) : About 200 cases of 3D CT image data of torso regions as well as brain vessel CT Images are collected and stored in RAID discs in the laboratory. All of these image data consist of normal parts of the human body (originally imaged because of existence of suspected disease(s)), pulmonary cancer, emphysema, or other abnormalities such as liver disease.
2)Development of a scheme for automatically recognizing anatomical normal structure : An algorithm for segmenting main internal organs fully automatically in torso regions was developed and evaluated the accuracy and precision in terms of segmentation and recognition by using the database described above. As an overall result, satisfied result was obtained with segmentation accuracy of larger than 70 %.
3)Development of a scheme for automatically detecting abnormal regions : Thoracic lesion (pulmonary nodule), emphysema, breast cancer (mass shadow), liver lesion (cirrhosis), colon polyp, and osteoporosis were automatically detected by the developed algorithms and we found that these initial results were accepted with detection accuracy of larger than 80 %).
4)We obtained successful results as shown in 2) and 3) for initial CAD schemes for detecting and recognizing mufti-diseases from 3D torso multi-slice CT images, and this will be merged as a CAD system for multi-diseases ; we are still working on this part.

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (21 results)

All 2005 2004 Other

All Journal Article (12 results) Book (2 results) Publications (7 results)

  • [Journal Article] Evaluation of osteoporosis in X-ray CT examination : A preliminary study for an automatic recognition algorithm for the central part of a vertebral body using abdominal X-ray CT images2005

    • Author(s)
      S.Nishihara, H.Fujita, T.Iida, et al.
    • Journal Title

      Computerized Medical Imaging and Graphics 29(in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Evaluation of osteoporosis in X-ray CT examination : A preliminary study for an automatic recognition algorithm for the central part of a vertebral body using abdominal X-ray CT images2005

    • Author(s)
      S.Nishihara, H.Fujita, T.Iida, et al.
    • Journal Title

      Computerized Medical Imaging and Graphics 29 (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Automatic segmentation of hepatic tissue and 3D volume analysis of cirrhosis in multi-detector row CT scans and MR imaging2004

    • Author(s)
      X.Zhang, W.Li, H.Fujita, et al.
    • Journal Title

      IEICE Trans.Inf.& Syst. E87-D・8

      Pages: 2138-2147

    • NAID

      110003214106

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 頭部CTA画像における脳血管領域の自動抽出の試み2004

    • Author(s)
      猪又聖美, 李 鎔範, 藤田広志, 他
    • Journal Title

      日本放射線技術学会雑誌 60・9

      Pages: 1325-1331

    • NAID

      110003461661

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Automatic recognition of lung lobes and fissures from multislice CT images2004

    • Author(s)
      X.Zhou, T.Hayashi, H.Fujita, et al.
    • Journal Title

      Proc.SPIE, Medical Imaging 2004 5370

      Pages: 1629-1633

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Normal anatomical-structure recognitions in high-resolution multi-slice CT images2004

    • Author(s)
      X.Zhou, N.Kamiya, H.Fujita, et al.
    • Journal Title

      Proc.of the 10th International Conference on Virtual Systems and MultiMedia (VSMM 2004)

      Pages: 75-81

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 腹部X線CT画像を利用した骨粗鬆症のコンピュータ支援診断-計測領域の自動抽出およびCT特徴量とBMD値の比較に対する試み-2004

    • Author(s)
      西原貞光, 藤田広志, 飯田忠行, 他
    • Journal Title

      生体医工学 42・1

      Pages: 7-15

    • NAID

      120006340730

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Automatic segmentation of hepatic tissue and 3D volume analysis of cirrhosis in multi-detector row CT scans and MR imaging2004

    • Author(s)
      X.Zhang, W.Li, H.Fujita, et al.
    • Journal Title

      IEICE Trans.Inf.& Syst. E87-D 8

      Pages: 2138-2147

    • NAID

      110003214106

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Preliminary study on automated detection of cerebral vessels from head CTA images2004

    • Author(s)
      S.Inomata, Y.Lee, D-Y.Tsai, et al.
    • Journal Title

      Japanese Journal of Radiological Technology 60・9

      Pages: 1325-1331

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Computer-aided diagnosis of osteoporosis using abdominal X-ray CT images Preliminary study of automated region extraction and comparison between BMD and values and CT features2004

    • Author(s)
      S.Nishihara, H.Fujita, T.Iida, et al.
    • Journal Title

      Trans.Jap.Soc.Medical and Biological Eng. 42・1

      Pages: 7-15

    • NAID

      120006340730

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Automatic segmentation of hepatic tissue and 3D volume analysis of cirrhosis in multi-detector row CT scans and MR imaging2004

    • Author(s)
      X.Zhang, W.Li, H.Fujita, et al.
    • Journal Title

      IEICE Trans.Inf. & Syst. E87-D・8

      Pages: 2138-2147

    • NAID

      110003214106

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Normal anatomical-structure recognitions in high-resolution multislice CT images2004

    • Author(s)
      X.Zhou, N.Kamiya, H.Fujita, et al.
    • Journal Title

      Proc. of the 10th International Conference on Virtual Systems and MultiMedia (VSMM 2004)

      Pages: 75-81

    • Related Report
      2004 Annual Research Report
  • [Book] 医用画像工学(第2版)2004

    • Author(s)
      岡部哲夫, 藤田広志(編著)
    • Total Pages
      332
    • Publisher
      医歯薬出版(株)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Book] Medical Image Engineering (2^<nd> Edition)2004

    • Author(s)
      T.Okabe, H.Fujita, eds.
    • Total Pages
      332
    • Publisher
      Ishiyaku-syuppan, Ltd, Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] 西原貞光, 藤田広志, 飯田忠行, 滝川 厚, 原 武史: "腹部X線CT画像を利用した骨粗鬆症のコンピュータ支援診断-計測領域の自動抽出およびCT特徴量とBMD値の比較に対する試み-"生体医工学. (in press).

    • Related Report
      2003 Annual Research Report
  • [Publications] 久山慶子, 福岡大輔, 原 武史, 小倉敏裕, 藤田広志: "複素自己回帰モデルによる凹領域認識を用いた大腸ポリープ像の自動検出"医用画像情報学会雑誌. 21・1. 137-142 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] 林 達郎, 周 向栄, 原 武史, 藤田広志, 横山龍二郎, 桐生拓司, 星 博昭: "気管支情報を用いた胸部マルチスライスCT画像における肺野区間の分類"電子情報通信学会論文誌D-II. J87-D-II・1. 357-360 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] T.Hara, A.Yamamoto, X.Zhou, S.Iwano, S.Itou, H.Fujita, T.Ishigaki: "Automated volume measurements of pulmonary emphysema on 3-D chest CT images"Proc.of CARS 2003 (International Congress Series). 1256. 1043-1048 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] X.Zhou, S.Kobayashi, T.Hayashi, N.Murata, T.Hara, H.Fujita, et al.: "Lung structure recognition : a further study of thoracic organ recognitions based on CT images"Proc. of CARS 2003 (International Congress Series). 1256. 1025-1030 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 小林晋士, 周 向栄, 原 武史, 藤田広志, 横山龍二郎, 桐生拓司, 星博昭, 他: "3次元体幹部CT画像における骨格の分類と胸郭の自動抽出"電子情報通信学会技術研究報告. MI2003-16. 25-30 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 岡部哲夫, 藤田広志(編著): "医用画像工学(改訂版)"医歯薬出版(株)(印刷中). 300 (2004)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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