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Computer-aided Diagnosis on Chest Radiograph : Clinical Usefulness of Temporal Subtraction for detection of Interval Changes

Research Project

Project/Area Number 15591285
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionNagasaki University

Principal Investigator

ASHIZAWA Kazuto  Nagasaki University, Hospital of Medicine of Dentistry, Assistant Professor, 医学部・歯学部付属病院, 講師 (90274662)

Co-Investigator(Kenkyū-buntansha) 林 邦昭  長崎大学, 大学院・医歯薬学総合研究科, 教授 (80039536)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2003: ¥1,500,000 (Direct Cost: ¥1,500,000)
KeywordsComputer-aided diagnosis / Temporal subtraction for detection of interval change / Chest radiography
Research Abstract

Temporal subtraction scheme, which is one of the computer-aided diagnosis, is the technique by which a previous chest radiograph is subtracted from a current radiograph in order to enhance interval changes. The purpose of this study is to evaluate the usefulness of this scheme on digital chest radiographs for the detection of interval changes in various lesions seen in daily clinical practice.
We performed the observer test as a retrospective study. Forty pairs of digital chest radiographs in 20 cases with interval changes including nodular opacity, localized consolidation, diffuse lung opacity and so on, and 20 cases without interval changes were used. Temporal subtraction images were obtained from a commercially available computer-aided diagnosis (CAD) system (Truedia/XR ; Mitsubishi Space Software, Japan). Eight observers provided their confidence levels for the presence or absence of interval changes without and with temporal subtraction. Their confidence levels were represented on … More a 5-point rating scale (5 : definitely absent, 4 : probably absent, 3 : possibly present, 2 : probably present, 1 : definitely present). The diagnostic performance of observers was improved with use of temporal subtraction in less experienced radiologists.
We used this scheme in daily clinical work, and evaluated its usefulness prospectively. Radiologists provided their confidence levels for the presence or absence of interval changes without subtraction on a 5-point rating scale. After that they changed their confidence levels with subtraction in needed. Although the majority of the cases in daily clinical practice were normal or showed no interval change, there were not a few cases in which subtraction images alerted radiologists to locations of missed lesions, or suggested that their interpretations were false positive.
In conclusion, the temporal subtraction scheme is useful in the detection of interval changes for various lesions seen in daily work, especially for less experienced radiologists. Less

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (12 results)

All 2005 2004 2003 2002

All Journal Article (11 results) Book (1 results)

  • [Journal Article] 胸部単純写真におけるコンピュータ支援診断の研究-経時的差分画像の臨床的有用性-2005

    • Author(s)
      芦澤和人・他
    • Journal Title

      INNERVISION 20・8

      Pages: 62-62

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Computer-aided diagnosis on chest radiograph : clinical usefulness of temporal subtraction for detection of interval change.2005

    • Author(s)
      Kazuto Ashizawa, et al.
    • Journal Title

      Innervision 20

      Pages: 62-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 胸部単純写真におけるコンピュータ支援診断の研究-経時的差分画像法の臨床的有用性-2005

    • Author(s)
      芦澤 和人 他
    • Journal Title

      INNERVISION 20・8

      Pages: 62-62

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Artificial neural networks (ANNs) for differential diagnosis of interstitial lung disease : results of a simulation test with actual clinical cases2004

    • Author(s)
      Hiroyuki Abe, Kazuto Ashizawa, et al.
    • Journal Title

      Acad Radiol 11・1

      Pages: 29-37

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Application of an artificial neural network to high-resolution CT : Usefulness in differential diagnosis of diffuse lung disease2004

    • Author(s)
      Aya Fukushima, Kazuto Ashizawa, et al.
    • Journal Title

      AJR 183・8

      Pages: 297-305

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Application of an artificial neural network to high-resolution CT : Usefulness in differential diagnosis of diffuse lung disease.2004

    • Author(s)
      Aya Fukushima, Kazuto Ashizawa, et al.
    • Journal Title

      AJR 183

      Pages: 297-305

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 胸部単純X線写真におけるコンピュータ支援診断(CAD)2003

    • Author(s)
      芦澤和人・他
    • Journal Title

      画像診断 23・6

      Pages: 680-687

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] コンピュータ支援診断 : 魅力と課題 びまん性肺疾患の鑑別診断に対するニューラルネットワークの応用2003

    • Author(s)
      芦澤和人・他
    • Journal Title

      日本放射線技術学会雑誌 59・11

      Pages: 1338-1360

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Computer-aided diagnosis in chest radiography.2003

    • Author(s)
      Kazuto Ashizawa, et al.
    • Journal Title

      Jpn J Clinical Radiology 23

      Pages: 680-687

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Computer-aided diagnosis : Application of an artificial neural network to differential diagnosis of diffuse lung disease.2003

    • Author(s)
      Kazuto Ashizawa, et al.
    • Journal Title

      Jpn J Radiol Technol 59

      Pages: 1338-1360

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Artificial neural networks (ANNs) for differential diagnosis of interstitial lung disease : results of a simulation test with actual clinical cases.2002

    • Author(s)
      Hiroyuki Abe, Kazuto Ashizawa, et al.
    • Journal Title

      Acad Radiol 9

      Pages: 13-17

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] コンピュータ支援診断、胸部単純X線診断 : 画像の成り立ちと読影の進め方(林 邦昭, 中田 肇 編著)2003

    • Author(s)
      林 邦昭, 芦澤和人・他
    • Total Pages
      5
    • Publisher
      秀潤社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary

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Published: 2003-04-01   Modified: 2016-04-21  

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