| Project/Area Number |
15591456
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kansai Medical University |
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Principal Investigator |
KAZUHIKO Yoshioka Kansai Medical University, Faculty of Medicine, Assistant Professor, 医学部, 講師 (30166912)
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| Co-Investigator(Kenkyū-buntansha) |
IWAMOTO Shigeyoshi Kansai Medical University, Faculty of Medicine, Instructor, 医学部, 助手 (00333196)
MORITA Mika Kansai Medical University, Faculty of Medicine, Instructor, 医学部, 助手 (50268372)
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| Project Period (FY) |
2003 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2003: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Dynamic graciloplasty / anal function / stoma / abdominoperineal resection / cancer of the rectum |
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| Research Abstract |
1) Improvement of surgical technique of dynamic graciloplasty
We have attempted to improve surgical technique of dynamic graciloplasty in two ways ; improvement of rectal continence after surgery and ability of evacuation. As to rectal continence we have tried to develop new training schedule for 8 weeks in order to obtain more effective program. For improvement of ability of rectal evacuation electrical stimulator has already been used.
2) Objective assessments for anal function
Clinical, physiological and anatomical assessments were carried out before and after the operation. We measured the functional parameters preoperatively. The same assessments were carried out before and after the electrical stimulation of the gracilis muscle and after closing the covering stoma. We have found that resting anal canal pressure increased after electrical stimulation.
3) Comparison between clinical outcomes after dynamic graciloplasty and those after abdominoperineal resection
Psychological impact of having permanent abdominal stoma and possible disordered defecation after the operation was assessed using scenario based questionnaire in patients who was the candidates of this operation and those who had previously undergone abdominoperineal resection. The assessments revealed that although body image not having permanent abdominal stoma is clearly important patients also seemed to value good anal functional after graciloplasty.
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