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The development and clinical application of osteoinductive bio-absorbable subperiosteum implant for orthodontic treatment.

Research Project

Project/Area Number 15592182
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionAichi-Gakuin University

Principal Investigator

GOTO Shigemi  Aichi-Gakuin University, School of Dentistry, Professor, 歯学部, 教授 (60142577)

Co-Investigator(Kenkyū-buntansha) KONDO Takamasa  Aichi-Gakuin University, School of Dentistry, Associate Professor, 歯学部, 助教授 (70221249)
MIYAZAWA Ken  Aichi-Gakuin University, School of Dentistry, Associate Professor, 歯学部, 助教授 (60301636)
Project Period (FY) 2003 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2003: ¥1,700,000 (Direct Cost: ¥1,700,000)
KeywordsOrthodontic Treatment / Anchorage / Poly Lactic acid / Bioabsobable polymer / Implant / Sputtering / Titanium plate / Clinical application / 矯正治療用固定源 / 骨膜下インプラント / 生体材料 / 骨形成因子 / 吸収性生体材料
Research Abstract

In orthodontic treatment, the securing of an anchor is one of the most important factors that must be taken into consideration in terms of developing a treatment plan and proceeding with that treatment. The clinical usefulness of orthodontic implants has now been widely accepted because they are not dependent on the degree of patient cooperation. However, the invasion of soft tissue and bone cannot be avoided, and it is necessary for orthodontic implants to be removed after treatment. In addition, since implants have become smaller, problems have arisen, such as the breakage of implants inside bone. Therefore, we have chosen to focus on the use of a bioabsorbable material for use as orthodontic implants.
Study 1 : The purpose of this study was to investigate the possibility of using bioabsorbable implants as orthodontic anchorage. All implants used in this study were made from poly-L-lactic acid (PLLA ; molecular weight : 200,000), a bioabsorbable bone-bonding material. The implants wer … More e placed in the mandibles of beagle dogs. After implantation, traction was immediately applied to the third premolars (P3s) using the implants as anchorage. After the completion of each study period (3 and 6months) following installation, a tensile test, histological examination, and molecular weight measurement were performed. Therefore the authors reported a utility as anchorage for orthodontic treatment of bioabsorbable material using a lower jaw of a dog. However, the initial intensity was 14.75kgf but the mean breaking strength of the 6 month-groups in which continuous orthodontic force was applied was 3.47 kgf while that of the 6 month-groups in which no continuous orthodontic force was applied was 1.98 kgf.
Study 2 : The aim of this study was to investigate the influence of coating by sputtering on the surface of implant for an extreme control.
The results obtained were as follows : 1.Tensile strength of absorbable implant material compared it in the control group which was not coated, and the rate of decline of a group coated by sputtering showed a significantly low value. 2.Molecular weight of absorbable implant material compared it in the control group which was not coated, and the molecular weight of a group coated by sputtering showed a significantly high value. As for the coating by sputtering to implant, the likelihood that was useful for an intensity control of bioabsorbable implant was suggested.
In these studies, we conducted in vivo evaluations and examinations of whether or not it is possible to apply implants made of polylactic acid for use as anchorage for orthodontic treatment. Less

Report

(5 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (12 results)

All 2007 2006 2005 2004 2003

All Journal Article (12 results)

  • [Journal Article] 矯正用固定源として応用する生体吸収性インプラントの表面処理が物性に与える影響2007

    • Author(s)
      青木泰樹, 八木橋敬介, 宮濁建, 小川清隆, 河合達志, 後藤滋巳
    • Journal Title

      愛院大歯誌 45(1)

      Pages: 165-170

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Influence of surface coating of a bioabsorbable implant for orthodontic anchorage in Vitro2007

    • Author(s)
      Taiju Aoki, Keisuke Yagihashi, Ken Miyazawa, Kiyotaka Ogawa, Tatsushi Kawai, Shigemi Goto
    • Journal Title

      The Aichi-Gakuin Journal of Dental Science Vol 45, No 1

      Pages: 165-170

    • NAID

      10019575634

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 歯科矯正用固定源として応用する生体吸収性インプラントの表面処理が物性に与える影響2007

    • Author(s)
      青木 泰樹, 八木橋 敬介, 宮澤 健, 小川 清隆, 河合 達志, 後藤 滋巳
    • Journal Title

      愛知学院大学歯学会誌 (In Press)

    • NAID

      10019575634

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 歯周病を伴う叢生症例の成人矯正治療 -固定源としてスケルタルアンカレッジを応用した1治験例-2006

    • Author(s)
      宮澤健, 蛭川幸史, 田渕雅子, 小川清隆, 金子道生, 白水紀充, 栗田賢一, 後藤滋巳
    • Journal Title

      愛院大歯誌 44(2)

      Pages: 219-227

    • NAID

      10021963318

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Orthodontic treatment of adult with crowding and periodontal disease using skeletal anchorage2006

    • Author(s)
      Ken Miyazawa, Koji Hirukawa, Masako Tabuchi, Kiyotaka Ogawa, Michio Kaneko, Norimitsu Shi- rozu, Kenichi Kurita, Shigemi Goto
    • Journal Title

      The Aichi-Gakuin Journal of Dental Science Vol 44, No 2

      Pages: 219-227

    • NAID

      10021963318

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The use of bioabsorbable implants as orthodontic anchorage in dogs2005

    • Author(s)
      T.Aoki, K.Ogawa, K.Miyazawa, T.Kawai, S.Goto
    • Journal Title

      Dental Materials Journal 24(4)

      Pages: 626-635

    • NAID

      110003495350

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The use of bioabsorbable Implants as orthodontic anchorage in dons2005

    • Author(s)
      Taiju Aoki, Kiyotaka Ogawa, Ken Miyazawa, Tatsushi Kawai, Shigemi Goto
    • Journal Title

      Materials Journal Vol 24, No 4

      Pages: 628-635

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The use of bioabsorbable implant as orthodontic anchorage in dogs.2005

    • Author(s)
      Taiju Aoki
    • Journal Title

      Dental Materials Journal 24・4

      Pages: 628-635

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 歯科矯正治療の確実な固定源として応用するメッシュ状チタン骨膜下インプラントの開発2004

    • Author(s)
      小川清隆, 丹羽健, 宮澤健, 青木泰樹, 後藤滋巳
    • Journal Title

      愛院大歯誌 42(4)

      Pages: 501-508

    • NAID

      10021963066

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of a titanium mesh plate subperiosteal implant Applied as orthodontic absolute anchorage.2004

    • Author(s)
      Kiyotaka Ogawa, Ken Miyazawa, Taiju Aoki, Shigemi Goto
    • Journal Title

      The Aichi-Gakuin Journal of Dental Science Vol 42, No 4

      Pages: 501-508

    • NAID

      10021963066

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 矯正治療におけるスケルタルアンカレッジの未来と展望2003

    • Author(s)
      宮澤 健, 後藤滋巳
    • Journal Title

      クイントエッセンスデンタルインプラントロジー 10(5)

      Pages: 59-65

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The future and prospects of skeletal anchorage for orthodontic treatment.2003

    • Author(s)
      Ken Miyazawa, Shigemi Goto
    • Journal Title

      Quintessence Dental Implantology Vol 10, No5

      Pages: 59-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary

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Published: 2003-04-01   Modified: 2016-04-21  

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