| Project/Area Number |
15592244
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | SONODA WOMAN'S UNIVERSITY (2006)
University of Hyogo (2004-2005)
College of Nursing Art and Science, Hyogo (2003) |
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Principal Investigator |
YAMAMOTO YUKIKO SONODA WOMAN'S UNIVERSITY, HUMAN HEALTH, Associate professor, 人間健康学部・人間看護学科, 准教授 (90254474)
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| Co-Investigator(Kenkyū-buntansha) |
UGAI KAZUHIRO UNIVERSITY of HYOGO, NURSING, Professor, 看護学部, 教授 (50151840)
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| Project Period (FY) |
2003 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 2006: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2005: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 2004: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2003: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | Handwashing / Alcohol-based hand rub / Disinfection / Irritation |
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| Research Abstract |
CDC guidelines for hands hygiene recommended that hands be disinfected by alcohol based hand rub for prevention of nosocomial infection, and it is used in a ward frequently. In this study, we focused on efficiency for removing bacteria from hands and detrimental effect of hands hygiene. Three agents were tested : Welpas, Gojo and non-antimicrobial soap.
For removing bacteria from hands alcohol based hand rubs were more effective than non-antimicrobial soap. In addition, there was a little number of the bacteria detected from hands by using Welpas, 1 hour after 10 times hand hygiene. Conversely there were great number of bacteria detected from hands by using non-antimicrobial soap.
Score of stratum corneum were significant decrease after 10 times hand hygiene by gojo. There were not significant change by Welpas or non-antimicrobial soap. There were not significant changes in the transepidarmal water loss (TEWL) by using each 3 agents. After hand hygiene (10 times per day for 3 days), there were no significant changes in score of stratum corneum and TEWL by using each 3 agents. Sebum did not decrease. After hand hygiene (10 times per day for 5 days), there were significant changes in the score of stratum corneum by using each 3 agents. TEWL were significant increase and sebum decrease by using non-antimicrobial soap. As visual skin damage, xeroderma and crack were often found. These skin damage were often found on a finger-tip or circumference of a nail. Skin damage score ware were increased by alcohol based hand rub, not significant increased by non-antimicrobial soap for 5 testing days. In addition, the number of the resident flora decreased by use of alcoholic hand rubs.
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