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三叉神経領域疼痛における上位中枢系の関与特異性と病態解明に関する研究

Research Project

Project/Area Number 15659476
Research Category

Grant-in-Aid for Exploratory Research

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

天笠 光雄  東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (00014332)

Co-Investigator(Kenkyū-buntansha) 木野 孔司  東京医科歯科大学, 歯学部附属病院, 助教授 (80143585)
宮岡 等  北里大学, 医学部, 教授 (40209862)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2005: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2004: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2003: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywords感覚閾値 / うつ / 口腔
Research Abstract

1 痛覚関連性心理的要素の解析
口腔顔面領域への感覚閾値とうつ状態との関連性が示唆されたことを踏まえ、精神状態のみならず、遺伝的関与が大いに考慮できる性格との関連性を検索し、口腔顔面領域における感覚閾値との関連性する心理的要素をより詳細に解析した。手背と口腔顔面領域としての舌尖における感覚閾値それぞれに関与する性格傾向に相違が認められた。
2 口腔顔面痛患者を対象とした解析
口腔顔面痛患者の協力を得て口腔顔面領域における感覚閾値と精神状態および性格との関連性を検索中である。健常人で得た結果の臨床現場へのフィードバックを行い臨床的意義の検討を進めた。

Report

(3 results)
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (16 results)

All 2005 2004 Other

All Journal Article (10 results) Publications (6 results)

  • [Journal Article] Clinical evaluation of the temporomandibular joint following orthonathic surgery〜Multiple logistic regression analysis〜2005

    • Author(s)
      Aoyama S., Kino K., Kobayashi J., Yoshimasu H., Amagasa T.
    • Journal Title

      J Med Dent Sci 52・2

      Pages: 109-114

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Subcutaneous Injections of a TNF-α Antagonistic peptide Inhibit Both Inflammation and Bone Resorption in Collagen-Induced Murine Arthritis.2005

    • Author(s)
      Kojima T., Aoki K., Nonaka K., Saito H., Azuma M., Iwai H., Bobby J.Varghese., Yoshimasu H., Baron R., Ohya K., Amagasa T.
    • Journal Title

      J.Med.Dent.Sci 52・1

      Pages: 91-99

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Perception of hypernasality and its physical correlates.2005

    • Author(s)
      Kozaki-Yamaguchi Y., Suzuki N., Fujita Y., Yoshimasu H., Akagi M., Amagasa T.
    • Journal Title

      Oral Science International 2・1

      Pages: 21-35

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Analysis of Birateral Neck Metastasis of Tongue Cancer.2005

    • Author(s)
      Ishii J., Yamashiro M., Yamaneo M., Ishikawa H., Iwaki H, Amagasa T
    • Journal Title

      Oral Science International 2・2

      Pages: 126-130

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Cyclin D1 gene numerical aberration is a predictive marker for occult cervical lymph, node metastasis in TNM stage I and II squamous cell carcinoma of the oral cavity.2005

    • Author(s)
      Myo K., Uzawa N., Miyamoto R., Sonoda I., Yuki Y, Amagasa T
    • Journal Title

      Cancer 104・12

      Pages: 2710-2716

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Poly (ethylene glycol) hydrogels cross-linked by hydrolyzable polyrotaxane containing hydrozyapatite particles as scaffolds for bone regeneration.2005

    • Author(s)
      Fujimoto M., Isobe M., Yamaguchi S., Amagasa T., Watanabe A., Ooya T, Yui N
    • Journal Title

      J.Biomater.Sci.Polymer Edn 16・12

      Pages: 1611-1621

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Relationship between oral sensory thresholds and depressive moods2005

    • Author(s)
      Watanabe, Yuko., Kino, Koji., Ishikawa, Takayuki., et al.
    • Journal Title

      Journal of Medical and Dental Sciences 52.3

      Pages: 73-80

    • NAID

      110001065279

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Sarcomas of the oral and maxillofacial region : a review of 32 cases in 25 years.2004

    • Author(s)
      Yamaguchi, S., Nagasawa, H., Fujii, E., Amagasa, T.
    • Journal Title

      Clin Oral Invest 8・1

      Pages: 52-55

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis.2004

    • Author(s)
      Ohyama, Y., Nifuji, A., Maeda, Y., Amagasa, T., Noda, M.
    • Journal Title

      Endocrinology 145.10

      Pages: 4685-4692

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Axillary nodal metastasis from oral and maxillofacial cancer : A Report of 3 Cases.2004

    • Author(s)
      Aung Lwin Oo., Yamaguchi, S., Iwaki, H., Amagasa, T.
    • Journal Title

      J Oral Maxillifac Surg 62

      Pages: 1019-1024

    • Related Report
      2004 Annual Research Report
  • [Publications] J.Ishii., K.Kino., J.Kobayashi, T.Amagasa: "Synovial chondromatosis of the temporomandibular joint : Long-term postoperative follow-up of the residual calcification"J Med Dent Sci. 50. 133-137 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] I.Ogura., T.Amagasa., J.Ishii., H.Iwaki., T.Kurabayasi, T.Sasaki: "Comparison of Clinical Characteristics and Outcome of Young and Older Patients with Oral Squamous Cell Carcinoma"Oral Med Pathol. 8. 21-26 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] N.Yamamoto., M.Isobe., A.Negishi., H.Yoshimasu., H.Shimokawa., K.Ohya., T.Amagasa, S.Hasugai: "Effects of autologous serum on osteoblastic differentiation in human bone marrow cells"J Med Dent Sci. 50. 63-69 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] R.Miyamoto., N.Uzawa., S.Nagaoka., Y.Hirata., T.Amagasa: "Prognostic significance of cyclin D1 amplification and overexpression in oral squamous cell carcinomas"Oral Oncology. 39. 610-618 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] R.Salingcarnboriboon., H.Yoshitake., K.Tsuji., M.Obihata., T.Amagasa., A.Nifuji, M.Noda: "Establishment of tendon-derived cell lines exhibiting pluripotent mesenchymal stem cell-like property"Experimental Cell Research. 287. 289-300 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] T.Nakagawa., H.Shibuya., R.Yoshimura., M.Miura., N.Okada., S.Kishimoto., T.Amagasa, K.Omura: "Neck node metastasis after successful brachtherapy for early stage tongue carcinoma"Radiotherapy and Oncology. 68. 129-135 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2021-12-07  

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