| Budget Amount *help |
¥39,650,000 (Direct Cost: ¥30,500,000、Indirect Cost: ¥9,150,000)
Fiscal Year 2019: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2018: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2017: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2016: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2015: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Outline of Final Research Achievements |
The applicability of innovative medical/neuro imaging systems would provide important advancements in cognitive brain research, and improve clinical diagnosis and management of neurological and psychiatric disorders. The goal of this study was to develop super-sensitive compact optically pumped atomic magnetometer (OPAM) module as well as a prototype type of innovative multimodal ultra-low field MRI (ULF-MRI) systems with OPAM. We developed a new K-Rb hybrid-type OPAM and demonstrate that the hybrid OPAM enabling simultaneous multi-location measurements of neuromagnetic fields. Meanwile, we succeeded to image the first MRI obtained at the magnetic resonance frequency of 5 kHz by using a prototype of OPAM-based ULF-MRI. This study also demonstrates the possibility of remotely detecting magnetic fields generated from superparamagnetic iron oxide nanoparticles using the same ULF-MRI system.
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