Neuro-rehabilitation using Artificial Neural Connection
| Project/Area Number |
15H01818
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Rehabilitation science/Welfare engineering
|
|---|
| Research Institution | Tokyo Metropolitan Institute of Medical Science (2017)
Kyoto University (2015-2016) |
|---|
Principal Investigator |
NISHIMURA Yukio 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, プロジェクトリーダー (20390693)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥41,210,000 (Direct Cost: ¥31,700,000、Indirect Cost: ¥9,510,000)
Fiscal Year 2017: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2015: ¥27,560,000 (Direct Cost: ¥21,200,000、Indirect Cost: ¥6,360,000)
|
|---|
| Keywords | リハビリテーション / トランスレーショナルリサーチ |
|---|
| Outline of Final Research Achievements |
Regaining the function of an impaired limb is highly desirable in individuals experiencing paralysis due to spinal cord injury and stroke. We documents volitionally-controlled, non-invasive stimulation to preserved spinal circuits can regain voluntary gait control in paraplegic individuals. Another series of study that is aim to elucidate neuronal mechanisms of regaining lost function using closed-loop stimulation, we demonstrated that monkeys with stroke were able to learn to use a brain-controlled electrical stimulation to the muscles, to regain volitional control of a hand. In a targeted manner, this closed-loop stimulation induced an adaptive change of cortical activities throughout an extensive cortical area. Thus, the closed-loop stimulation imparted a new function for limb control to a connected cortical site and triggered cortical adaptation in order to regain impaired motor function after neural damage.
|
Report
(4 results)
Research Products
(56 results)
-
-
-
[Journal Article] アスリートの脳を理解する2017
Author(s)
西村幸男,野崎大地
-
Journal Title
Journal of the Society of Instrument and Control Engineers2017
Volume: 56
Pages: 584-587
NAID
Related Report
-
-
-
-
-
[Journal Article] Histological and electrophysiological analysis of the corticospinal pathway to forelimb motoneurons in common marmosets.2015
Author(s)
Kondo T, Yoshihara Y, Saito-Yoshino K, Sekiguchi T, Kosugi A, Miyazaki Y, Nishimura Y, Okano HJ, Nakamura M. Okano H, Isa T, Ushiba J
-
Journal Title
Neurosci Res
Volume: 98
Pages: 35-44
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
