| Project/Area Number |
15H01828
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Sports science
|
|---|
| Research Institution | University of Tsukuba |
|---|
Principal Investigator |
SOYA Hideaki 筑波大学, 体育系, 教授 (50221346)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
McHugh Thomas 国立研究開発法人理化学研究所, 脳科学総合研究センター, チームリーダー (50553731)
功刀 浩 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第三部, 部長 (40234471)
大石 久史 筑波大学, 医学医療系, 准教授 (30375513)
岡本 正洋 筑波大学, 体育系, 助教 (30726617)
松井 崇 筑波大学, 体育系, 助教 (80725549)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥40,300,000 (Direct Cost: ¥31,000,000、Indirect Cost: ¥9,300,000)
Fiscal Year 2017: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2016: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Fiscal Year 2015: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
|
|---|
| Keywords | 運動 / 認知機能 / fMRI / 意欲 / DREADDシステム / 低強度運動 / ドーパミン / DREADD / 海馬歯状回 |
|---|
| Outline of Final Research Achievements |
Stress and/or lack of exercise cause lower vitality within our body and mind, especially cause cognitive dysfunction that related to hippocampus. To solve this problem, it is necessary to develop the new exercise prescription for increasing continuously willing on exercise. In this study, the effect of low intensity exercise (LE) and high intensity interval training (HIT) was both examined on human and animals studies. Our results showed that HIT could also enhance cognitive function just as ME did. In addition, acute mild exercise in human also revealed enhanced hippocampal function. Furthermore, LE was also effective for improving cognitive function in the disease animal model of cognitive dysfunction. In summary, our results demonstrated and established the new exercise prescription and is expecting to become the basic concepts for applying to clinical practice in the future.
|
