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Early Earth made and build essential biomolecules

Research Project

Project/Area Number 15H02144
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Petrology/Mineralogy/Economic geology
Research InstitutionTohoku University

Principal Investigator

Takeshi Kakegawa  東北大学, 理学研究科, 教授 (60250669)

Co-Investigator(Kenkyū-buntansha) 古川 善博  東北大学, 理学研究科, 准教授 (00544107)
小林 敬道  国立研究開発法人物質・材料研究機構, その他部局等, その他研究員 (20260028)
関根 利守  広島大学, 理学研究科, 特任教授 (70343829)
Research Collaborator TANIGUCHI TAKSHI  国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, グループリーダー (80354413)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥43,420,000 (Direct Cost: ¥33,400,000、Indirect Cost: ¥10,020,000)
Fiscal Year 2017: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥33,800,000 (Direct Cost: ¥26,000,000、Indirect Cost: ¥7,800,000)
Keywords生命起源 / アミノ酸 / 核酸塩基 / 初期地球 / 隕石衝突 / ペプチド / リボース / 核酸 / 粘土鉱物 / メチオニン / ヌクレオチド
Outline of Final Research Achievements

We performed following series of experiments to approach essential problems for origin of life: (1) Simulation experiment for meteorite impact on the early oceans, (2) experiments for ribose and nucleotide formations assuming early oceanic and evaporitic environments, and (3) biotic-like peptide formation assuming inside of Hadean marine sediments. We were successful to form various amino acids and pyrimidine nucleobases by experiment (1). Ribose was selectively stabilized and nucleotide was formed using Luneburgite by experiment (2). We were also able to form aspartic acid peptides and methionine peptides under high P and T conditions, which were the same range of deep marine sediments. In particular, prebiotic sulfur cycle, which is identical biotic sulfur cycle, was realized during the methionine peptide formation. All results suggest how dynamics of the early Earth were important to promote chemical evolution for origin of life.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (56 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (2 results) Journal Article (17 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 13 results,  Open Access: 7 results,  Acknowledgement Compliant: 7 results) Presentation (37 results) (of which Int'l Joint Research: 25 results,  Invited: 12 results)

  • [Int'l Joint Research] Ffame(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Firebird Biomolecule Science LLD(米国)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Racemization of Valine by Impact-Induced Heating2018

    • Author(s)
      Furukawa Y., Takase A., Sekine T., Kakegawa T., Kobayashi T.
    • Journal Title

      Orig. Life Evol. Bios.

      Volume: 48 Issue: 1 Pages: 131-139

    • DOI

      10.1007/s11084-017-9539-0

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microbial diversity and iron oxidation at Okuoku-hachikurou Onsen, a Japanese hot spring analog of Precambrian iron formation2017

    • Author(s)
      Ward L.M., Idei A., Kakegawa T., Fischer W.W., McGlynn S.E.
    • Journal Title

      Geobiology

      Volume: 15 Issue: 6 Pages: 817-835

    • DOI

      10.1111/gbi.12266

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Borate and the origin of RNA: A model for the precursors to life2017

    • Author(s)
      Furukawa Y. and Kakegawa T.
    • Journal Title

      Elements

      Volume: 13 Issue: 4 Pages: 261-265

    • DOI

      10.2138/gselements.13.4.261

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Huang, Y. Furukawa, T. Otake, T. Kakegawa2017

    • Author(s)
      Effects of glycine, water, ammonia, and ammonium bicarbonate on the oligomerization of methionine
    • Journal Title

      Origin of Life and Evolution of Biospheres

      Volume: 印刷中 Issue: 2 Pages: 145-160

    • DOI

      10.1007/s11084-016-9518-x

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microbial nitrogen cycle enhanced by continental input recorded in the Gunflint Formation2017

    • Author(s)
      Ishida A., Hashizume K., and Kakegawa T.
    • Journal Title

      Geoch. Perspec. Letters

      Volume: 4 Pages: 13-18

    • DOI

      10.7185/geochemlet.1729

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adsorption of RNA on mineral surfaces and mineral precipitates2017

    • Author(s)
      Elisa Biondi, Yoshihiro Furukawa, Jun Kawai, and Steven A. Benner
    • Journal Title

      Beilstein J. Org. Chem.

      Volume: 13 Pages: 393-404

    • DOI

      10.3762/bjoc.13.42

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Morphological changes of olivine grains reacted with amino acid solutions by impact process2017

    • Author(s)
      Umeda Y., Takase A., Fukunaga N., Sekine T., Kobayashi T., Furukawa Y., Kakegawa T.
    • Journal Title

      Physics and Chemistry of Minerals

      Volume: 44 Issue: 3 Pages: 203-212

    • DOI

      10.1007/s00269-016-0849-y

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 鉄が生み、鉄と共に育った地球生命2017

    • Author(s)
      掛川武
    • Journal Title

      日本鉄鋼協会会報ふぇらむ

      Volume: 22 Pages: 25-28

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 隕石衝突がもらした奇跡 「生命誕生」のメカニズム2017

    • Author(s)
      掛川武
    • Journal Title

      ヘルシスト

      Volume: 244 Pages: 2-7

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 太古の岩石が語る地球最古の微生物活動ー38~37億年前の海で生息していたことが明らかに2017

    • Author(s)
      掛川武
    • Journal Title

      生物の科学 遺伝

      Volume: 71 Pages: 133-138

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Evaporite borate-containing mineral ensembles make phosphate available and regiospecifically phosphorylate ribonucleosides. Borate as a problem solver in prebiotic chemistry2016

    • Author(s)
      Kim, H. J., Furukawa Y., Kakegawa T., Bita A., Scorei R., *Benner S.A.
    • Journal Title

      Angewandte Chemie International Edit

      Volume: 55 Issue: 51 Pages: 15816-15820

    • DOI

      10.1002/anie.201608001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Survivability and reactivity of glycine and alanine in early oceans: effects of meteorite impacts2016

    • Author(s)
      Umeda Y., Fukunaga N., Sekine T., Furukawa Y., Kakegawa T., Kobayashi T., Nakazawa
    • Journal Title

      Journal of Biological Physics

      Volume: 42 Issue: 1 Pages: 177-198

    • DOI

      10.1007/s10867-015-9400-5

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 「地球が生命をつくった」仮説の検証ー地球化学と化学の接点2016

    • Author(s)
      掛川武
    • Journal Title

      化学

      Volume: 71 Pages: 68-69

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Effect of Silicate, Phosphate, and Calcium on the stability of aldopentose2015

    • Author(s)
      Nitta S., Furukawa Y., and Kakegawa T.
    • Journal Title

      Origin of Life and Evolution of Early Biosphere

      Volume: 46 Issue: 2-3 Pages: 189-202

    • DOI

      10.1007/s11084-015-9472-z

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Occurrence of Tourmaline in Metasedimentary Rocks of the Isua Supracrustal Belt, Greenland: Implications for Ribose Stabilization in Hadean Marine Sediments2015

    • Author(s)
      Mishima S., Ohtomo Y. and Kakegawa T.
    • Journal Title

      Orig Life Evol Biosph

      Volume: 46 Issue: 2-3 Pages: 247-271

    • DOI

      10.1007/s11084-015-9474-x

    • NAID

      130005492394

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Nucleobase and amino acid formation through impacts of meteorites on the early ocean2015

    • Author(s)
      Furukawa Y., Nakazawa H., Sekine T., Kobayashi T. & Kakegawa T.
    • Journal Title

      Earth and Planetary Science Letters

      Volume: 426 Pages: 216-222

    • DOI

      10.1016/j.epsl.2015.07.049

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Shock wave synthesis of amino acids from solutions of ammonium formate and ammonium bicarbonate2015

    • Author(s)
      Suzuki C., Furukawa Y., Kobayashi T., Sekine T., Nakazawa H., Kakegawa T.
    • Journal Title

      Geochemistry Geophysics and Geosystems

      Volume: 16 Issue: 7 Pages: 2382-2394

    • DOI

      10.1002/2015gc005783

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Prebiotic Sugars on the Early Earth2018

    • Author(s)
      Y. Furukawa
    • Organizer
      Gordon Research Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Formations of prebiotic nucleotide and peptide around Hadean juvenile crusts2018

    • Author(s)
      T. Kakegawa
    • Organizer
      Water Dynamics Workshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 初期地球表層生態系の解明:Moodies Group Drilling Project2018

    • Author(s)
      掛川武
    • Organizer
      J-DESC Future Scientific Drilling Workshop 科学掘削の未来
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] アミノ酸から細胞分裂まで:東北大の強みを生かした生命起源研究の新展開2018

    • Author(s)
      掛川武
    • Organizer
      東北大FRIST Annual Meeting
    • Related Report
      2017 Annual Research Report
  • [Presentation] Early oxygenic photosynthesis in 3.2 Ga Fig Tree Group, Barberton Greenstone Belt?2017

    • Author(s)
      Kakegawa T.
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Proto-arc model for ribose and nucleotide genesis: information from Isua Supracrustal Belt2017

    • Author(s)
      Kakegawa T.
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Earth made the first life2017

    • Author(s)
      Kakegawa T.
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Drilling proposal of 3.2 Ga Moodies Group in Barberton Greenstone Belt: high resolution reconstruction of surface envirnment and biosphere of middle Archean Earth2017

    • Author(s)
      Kakegawa,T.,Christoph Heubeck
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Microbial nitrogen cycle enhanced by the continental input recorded in the Paleoproterozoic Gunflint Formation2017

    • Author(s)
      Ishida,A.,Hashizume,K.,Kakegawa,T.
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Microstructure and geochemistry of organic matters associated with iron minerals in 3.2 Ga banded iron formations, Moodies Group, Barberton Green stone Belt, South Africa2017

    • Author(s)
      Nakajima,R.,Ohtomo,Y.,Otake,T.,Kakegawa,T., Sato,T.
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Depositional environment of graphite-bearing metasedimentary rocks and banded iron formations in >3.7 Ga Isua Supracrustal Belt, West Greenland,2017

    • Author(s)
      Ohtomo,Y.,Kato,T.,Otake,T.,Kakegawa,T
    • Organizer
      Japan Geoscience Union-American Geophysical Union Joint Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Clay mineral assists borate to stabilize ribose2017

    • Author(s)
      Y. Furukawa A. Nitta, T. Kakegawa, S. A. Benner
    • Organizer
      AbScicon
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] High Abundance of Borate in Hadean Proto-Arc Environments to Form Prebiotic Ribose and Nucleotide?: Geological Constraints from Isua Supracrustal Belt2017

    • Author(s)
      T.Kakegawa
    • Organizer
      XVIIIth International Conference on the Origin of Life
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Amino acid formation by asteroid impacts on ammonia-free oceans2017

    • Author(s)
      Y. Furukawa, Y. Takeuchi, T. Kobayashi, T. Sekine, T. Kakegawa
    • Organizer
      XVIIIth International Conference on the Origin of Life
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Microbial community associated with 2.7 Ga submarine hydrothermal activities: geochemical and STEM studies on kerogen from Canadian greenstone belts2017

    • Author(s)
      Y. Kunitake, T. Kakegawa, Y. Watanabe
    • Organizer
      Goldschmidt Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Significance of Cr-rich sedimentary rocks in 3.2 Ga Fig Tree Group, Barberton Greenstone Belt, S. Africa2017

    • Author(s)
      T.KAKEGAWA, T. SAKAI, N. AKIHIRO
    • Organizer
      Goldschmidt Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Micro to nanoscale observations of carbonaceous matters in 3.2 Ga Banded iron formations, Sheba Gold mine, Moodies Group, Barberton Greenstone Belt and >3.7 Ga schist, Isua Supracrustal Belt2017

    • Author(s)
      Y. OHTOMO, R. NAKAJIMA, T. OTAKE, T. KAKEGAWA
    • Organizer
      Goldschmidt Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 初期海洋への隕石衝突を模擬した有機物合成実験におけるアンモニアの影響2017

    • Author(s)
      竹内悠人, 古川善博, 小林敬道, 関根利守, 掛川武
    • Organizer
      日本地球化学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ホルモース反応におけるホウ酸の影響の定量的評価2017

    • Author(s)
      古川善博, 阿部千晶, 掛川武
    • Organizer
      日本地球化学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] リボースの安定性に対するカオリナイトの影響2017

    • Author(s)
      新田あゆみ, 古川善博, 掛川武
    • Organizer
      日本地球化学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Significance of oxide sedimentary rocks in 3.2 Ga MoodiesGroup, Barberton Greenstone Belt, S. Africa2017

    • Author(s)
      T. Kakegawa
    • Organizer
      ICDP Moodies Drilling Field Workshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The tectonic evolution of Isua Supracrustal Belt and its implication to origin of life2016

    • Author(s)
      Takeshi Kakegawa
    • Organizer
      Astrobiology workshop ”Search for life: from early earth to exoplanets”
    • Place of Presentation
      Buy Nhon, Vietnam
    • Year and Date
      2016-12-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 地球における生物の痕跡の探査2016

    • Author(s)
      掛川武
    • Organizer
      アストロバイオロジーネットワーク年会
    • Place of Presentation
      仙台、日本
    • Year and Date
      2016-09-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] 初期海洋への隕石衝突を模擬した有機物合成実験における蛇紋石の影響2016

    • Author(s)
      竹内悠人、古川善博、掛川武
    • Organizer
      アストロバイオロジーネットワーク年会
    • Place of Presentation
      仙台、日本
    • Year and Date
      2016-09-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] 初期地球におけるオリゴヌクレオチドの生成に関する最近の研究と問題点2016

    • Author(s)
      古川善博
    • Organizer
      アストロバイオロジーネットワーク年会
    • Place of Presentation
      仙台、日本
    • Year and Date
      2016-09-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] 高温高圧におけるアスパラギン酸のペプチド化実験2016

    • Author(s)
      岡田陽介、古川善博、掛川武
    • Organizer
      アストロバイオロジーネットワーク年会
    • Place of Presentation
      仙台、日本
    • Year and Date
      2016-09-22
    • Related Report
      2016 Annual Research Report
  • [Presentation] Proto-arc model for chemical evolution: Constraints from geological information of Isua Supracrustal Belt2016

    • Author(s)
      Takeshi Kakegawa
    • Organizer
      Goldschmidt Conference
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Formation of life’s building blocks by meteorite impacts2016

    • Author(s)
      Furukawa Y. Nakazawa H., Sekine T., Kobayashi T. amd Kakegawa T.
    • Organizer
      Goldschmidt Conference
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect pH on aspartic acid peptide formations under high temperature and pressure2016

    • Author(s)
      Okada Y., Furukawa Y. and Kakegawa T.
    • Organizer
      Goldschmidt Conference
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of serpentine on the organic synthesis in impacts of meteorites on the early ocean2016

    • Author(s)
      Takeuchi Y., Furukawa Y., Kobayashi T., Nakazawa H., Sekine T. and Kakegawa T.
    • Organizer
      Goldschmidt Conference
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bimodal carbon isotope compostions of organic matter at ca. 2.7 Ga Wawa Greenstone belt, Schreiber , Canada2016

    • Author(s)
      Kunitake Y and Kakegawa T.
    • Organizer
      Goldschmidt Conference
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Organic synthesis by meteorite impact2016

    • Author(s)
      Yoshihiro Furukawa
    • Organizer
      Pre-Forum Meeting on Future Cosmochemistry for the JSPS “Science in Japan Forum 2016”
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nucleobase and amino acid formation by ocean impact on the Hadean Earth2015

    • Author(s)
      Y. Furukawa
    • Organizer
      Pacifichem Congress
    • Place of Presentation
      Hawaii、U.S.A
    • Year and Date
      2015-12-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Evidence of the earliest life2015

    • Author(s)
      T.Kakegawa
    • Organizer
      Astrobiology Scientific Conference
    • Place of Presentation
      Kiel, Germany
    • Year and Date
      2015-12-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 初期地球が作ったアミノ酸2015

    • Author(s)
      掛川武
    • Organizer
      新アミノ酸研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-12-07
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Traces of early life in 3.8 Ga rocks2015

    • Author(s)
      T.Kakegawa
    • Organizer
      Department seminar at Quebec University
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] グリーンランド・イスア表成岩体の変成堆積岩中でのトルマリンの産出:冥 王代海洋堆積物中におけるリボース安定化に対する示唆2015

    • Author(s)
      三嶋 慎平,大友 陽子,掛川 武
    • Organizer
      日本地球化学会
    • Place of Presentation
      横浜
    • Year and Date
      2015-09-16
    • Related Report
      2015 Annual Research Report

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Published: 2015-04-16   Modified: 2022-08-22  

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