| Budget Amount *help |
¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2018: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2017: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2016: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2015: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Outline of Final Research Achievements |
The ability of axons to regenerate after damage is a fundamental and conserved property of neurons governed by intrinsic processes that regulate axon growth potential. However, these intrinsic signaling mechanisms have yet to be fully elucidated. The nematode Caenorhabditis elegans has recently emerged as an attractive model to dissect the mechanisms of axon regeneration in the mature nervous system. In this study, we identified a number of genes that regulate axon regeneration in C. elegans. Analysis of these genes shed new light on the regulation of axonal regeneration.
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