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Subclinical atherosclerosis and brain atrophy in the general Japanese women

Research Project

Project/Area Number 15H02528
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene and public health
Research InstitutionShiga University of Medical Science

Principal Investigator

Miura Katsuyuki  滋賀医科大学, 医学部, 教授 (90257452)

Co-Investigator(Kenkyū-buntansha) 藤吉 朗  滋賀医科大学, 医学部, 准教授 (10567077)
村田 喜代史  滋賀医科大学, 医学部, 教授 (20127038)
有馬 久富  福岡大学, 医学部, 教授 (20437784)
ABBOTT ROBERT  滋賀医科大学, アジア疫学研究センター, 特任教授 (20722416)
椎野 顯彦  滋賀医科大学, 神経難病研究センター, 准教授 (50215935)
門田 文  滋賀医科大学, 医学部, その他 (60546068)
上島 弘嗣  滋賀医科大学, アジア疫学研究センター, 特任教授 (70144483)
高嶋 直敬  滋賀医科大学, 医学部, 助教 (80435883)
野崎 和彦  滋賀医科大学, 医学部, 教授 (90252452)
久松 隆史  滋賀医科大学, 医学部, 客員准教授 (60710449)
Co-Investigator(Renkei-kenkyūsha) HORIE Minoru  滋賀医科大学, 医学部, 教授 (90183938)
TOOYAMA Ikuo  滋賀医科大学, 神経難病研究センター, 教授 (20207533)
MAEGAWA Hiroshi  滋賀医科大学, 医学部, 教授 (00209363)
SEKIKAWA Akira  滋賀医科大学, 医学部, 客員准教授 (10216525)
OKAMURA Tomonori  慶應義塾大学, 医学部, 教授 (00324567)
OHKUBO Takayoshi  帝京大学, 医学部, 教授 (60344652)
TABARA Yasuharu  京都大学, ゲノム医学センター, 准教授 (00268749)
OHNO Seiko  滋賀医科大学, アジア疫学研究センター, 特任講師 (20610025)
KADOWAKI Sayaka  滋賀医科大学, 医学部, 客員助教 (60510344)
MIYAGAWA Naoko  滋賀医科大学, 医学部, 特任助教 (20388169)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥46,410,000 (Direct Cost: ¥35,700,000、Indirect Cost: ¥10,710,000)
Fiscal Year 2017: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2016: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2015: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Keywords認知症 / 動脈硬化 / 女性 / 疫学 / 一般女性 / 脳萎縮 / 予防
Outline of Final Research Achievements

The aim of this study is to investigate the prevalence of subclinical atherosclerosis and the brain atrophy in the general population of Japanese women, and to clarify the relevant factors. Our target number of subjects of this study was 800. In 2015-2017, we have successfully conducted survey on 266 women, who were randomly sampled from local residents in Kusatsu city, Shiga. We have performed chest and abdominal computed tomography, head magnetic resonance imaging, carotid artery ultrasound, cognitive function test, physical function tests, blood pressure, blood and urine test, and electrocardiogram to the subjects. We will continue the survey on approximately 500 women additionally in 2018-2021.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (17 results)

All 2018 2017 Other

All Journal Article (4 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (10 results) (of which Int'l Joint Research: 5 results) Remarks (3 results)

  • [Journal Article] Reduced Lung Function and Cerebral Small Vessel Disease in Japanese Men: the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)2018

    • Author(s)
      Seto-Yukimura R, Ogawa E, Hisamatsu T, Torii S, Shiino A, Nozaki K, Fujiyoshi A, Miura K, Nakano Y, Ueshima H
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 25 Issue: 10 Pages: 1009-1021

    • DOI

      10.5551/jat.42127

    • NAID

      130007493888

    • ISSN
      1340-3478, 1880-3873
    • Year and Date
      2018-10-01
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Coronary Artery Calcification with Estimated Coronary Heart Disease Risk from Prediction Models in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)2018

    • Author(s)
      Tai P, Fujiyoshi A, Arima H, Tanaka-Mizuno S, Hisamatsu T, Kadowaki S, Kadota A, Zaid M, Sekikawa A, Yamamoto T, Horie M, Miura K, Ueshima H
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 25 Issue: 6 Pages: 477-489

    • DOI

      10.5551/jat.42416

    • NAID

      130007382558

    • ISSN
      1340-3478, 1880-3873
    • Year and Date
      2018-06-01
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Self-reported Sleep Duration and Subclinical Atherosclerosis in a General Population of Japanese Men2018

    • Author(s)
      Suzuki S, Arima H, Miyazaki S, Fujiyoshi A, Kadota A, Takashima N, Hisamatsu T, Kadowaki S, Zaid M, Torii S, Horie M, Murata K, Miura K, Ueshima H
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 25 Issue: 2 Pages: 186-198

    • DOI

      10.5551/jat.40527

    • NAID

      130006328445

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Coronary Artery Calcium and Carotid Artery Intima Media Thickness and Plaque: Clinical Use in Need of Clarification2017

    • Author(s)
      Maryam Zaid, Akira Fujiyoshi, Aya Kadota, Robert D. Abbott, Katsuyuki Miura
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 24 Issue: 3 Pages: 227-239

    • DOI

      10.5551/jat.RV16005

    • NAID

      130005397941

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] The Association Between Coronary ArteryCalcium And The Cerebral Small VesselDisease: A Community Based Cross SectionalStudy2018

    • Author(s)
      Md Maruf Haque Khan; Akira Fujiyoshi; Katsuyuki Miura; Takashi Hisamatsu; Sayuki Torii; Sentaro Suzuki; Akihiko Shiino; Kazuhiko Nozaki; Takayoshi Ohkubo; Ayako Kunimura; Hirotsugu Ueshima; for the SESSA Research Group
    • Organizer
      American Heart Association International StrokeConference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Intracranial artery stenosis and the association with conventional risk factors of cardiovascular disease in general population of Japanese:SESSA study2017

    • Author(s)
      Satoshi Shitara, Akira Fujiyoshi, Takashi Hisamatsu, Hisatomi Arima, Akihiko Shiino, Kazuhiko Nozaki, Katsuyuki Miura, Hirotsugu Ueshima
    • Organizer
      AHA Epi/Lifestyle2017
    • Place of Presentation
      Portland, Oregon, USA
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] Coronary Artery Structural Remodeling by Computed Tomography and Cardiovascular Disease; the Coronary Artery Risk Development in Young Adults (CARDIA) Study2017

    • Author(s)
      J. Jeffrey Carr, Katsuyuki Miura, Hirotsugu Ueshima, Akira Fujiyoshi, Takashi Hisamatsu, Akira Sekikawa
    • Organizer
      AHA Epi/Lifestyle2017
    • Place of Presentation
      Portland, Oregon, USA
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 飲酒習慣と腹部脂肪分布(内臓脂肪・皮下脂肪)との関連の検討2017

    • Author(s)
      炭 昌樹, 久松隆史, 藤吉 朗, 門田 文, 宮川尚子, 近藤慶子, 門脇紗也佳, Zaid Maryam, 佐藤 敦, 有馬久富, 三浦克之, 上島弘嗣, for the SESSA Research Group
    • Organizer
      第53回日本循環器病予防学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Association of serum n-3 polyunsaturatedfatty acids with silent cerebral vascularlesions in a Japanese male population2017

    • Author(s)
      Keiko Kondo, Hisatomi Arima, Takashi Hisamatsu, Akira Fujiyoshi, Aya Kadota, Akira Sekikawa, Sayuki Torii, Sentaro Suzuki, Akihiko Shiino, Kazuhiko Nozaki, Naoko Miyagawa, Hiroshi Maegawa, Kiyoshi Murata, Katsuyuki Miura, Hirotsugu Ueshima, for the SESSA Research Group
    • Organizer
      21st International Epidemiological Association
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship of carotid intima-mediathickness measurements with coronary arterycalcification in a Japanese general population:SESSA2017

    • Author(s)
      Maryam Zaid, Akira Fujiyoshi, Takashi Hisamatsu, Aya Kadota, Sakaya Kadowaki, Atsushi Satoh, Akira Sekikawa, Minoru Horie, Katsuyuki Miura, and Hirotsugu Ueshima, for the SESSA Research Group.
    • Organizer
      21st International Epidemiological Association
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Difference between home and office bloodpressure measurements, and determinants forthe difference in a randomly selectedJapanese male population2017

    • Author(s)
      門脇紗也佳、門脇崇, 寳澤篤, 藤吉朗, 久松隆史, 佐藤敦, 田中佐智子, 岡村智教, 大久保孝義, 三浦克之, 上島弘嗣, SESSA研究グループ
    • Organizer
      21st International Epidemiological Association
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Smoking associates with higher incidence andprogression of coronary atherosclerosis in acommunity-based sample of Japanese men:The Shiga Epidemiological Study ofSubclinical Atherosclerosis (SESSA)2017

    • Author(s)
      Tai Pham; Akira Fujiyoshi; Takashi Hisamatsu; Aya Kadota; Sayaka Kadowaki; Maryam Zaid; Minoru Horie; Katsuyuki Miura; Hirotsugu Ueshima; for the SESSA Research Group
    • Organizer
      第52回日本アルコールアディクション医学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Drinking status and cognitive function amongcognitively intact elderly Japanese men2017

    • Author(s)
      Ali T. Siddiquee, Aya Kadota, Akira Fujiyoshi, Naoko Miyagawa, Keiko Kondo, Hiromi Yamauchi, Takahiro Ito, Katsuyuki Miura, Hirotsugu Ueshima, for the SESSA Research Group
    • Organizer
      第52回日本アルコールアディクション医学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The effect of alcohol drinking and smoking onmodified atherogenic high density lipoproteincholesterol levels in a Japanese generalpopulation2017

    • Author(s)
      Tomonori Okamura, Tatsuya Sawamura, Katsuyuki Miura, Akira Fujiyoshi, Naoko Miyagawa, Kazuyo Kuwabara, Naomi Miyamastu, Hirotsugu Ueshima, and SESSA Research Group
    • Organizer
      European Society for Biomedical Research onAlcoholism (ESBRA) Congress
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Remarks] アジア疫学研究センター

    • URL

      https://cera.shiga-med.ac.jp/

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report 2015 Annual Research Report
  • [Remarks] 動脈硬化と認知症に関する疫学研究 滋賀動脈硬化疫学研究 SESSA セッサ

    • URL

      https://hs-web.shiga-med.ac.jp/sessa/

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
  • [Remarks] 動脈硬化と認知症に関する疫学研究 滋賀動脈硬化疫学研究 SESSA セッサ

    • URL

      https://hs-web.shiga-med.ac.jp/sessa/

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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