• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Interdisciplinary study of obstetric management and gynecological rare tumor in Vietnam

Research Project

Project/Area Number 15H02660
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Obstetrics and gynecology
Research InstitutionNagoya University

Principal Investigator

FUMITAKA KIKKAWA  名古屋大学, 医学系研究科, 教授 (40224985)

Co-Investigator(Kenkyū-buntansha) 梶山 広明  名古屋大学, 医学系研究科, 准教授 (00345886)
山本 英子  名古屋大学, 医学系研究科, 准教授 (10432262)
新美 薫  名古屋大学, 医学部附属病院, 病院講師 (20571334)
玉腰 浩司  名古屋大学, 医学系研究科(保健), 教授 (30262900)
炭竈 誠二  名古屋大学, 医学系研究科, 特任講師 (50378121)
小谷 友美  名古屋大学, 医学部附属病院, 准教授 (70359751)
青山 温子  名古屋大学, 医学系研究科, 教授 (40184056)
柴田 清住  名古屋大学, 医学系研究科, 准教授 (90335026)
Project Period (FY) 2015-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥39,000,000 (Direct Cost: ¥30,000,000、Indirect Cost: ¥9,000,000)
Fiscal Year 2019: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2018: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2017: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2016: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Keywords帝王切開 / 周産期管理 / 絨毛性疾患 / デング熱 / 胚細胞腫瘍 / 婦人科がん / ベトナム / 悪性胚細胞腫瘍 / 腫瘍免疫 / 産後過多出血 / 周産期医療 / 産後出血 / 癒着胎盤 / 周産期 / 妊娠高血圧症候群 / 婦人科腫瘍
Outline of Final Research Achievements

For the purpose of not only the development of obstetrics and gynecology in Vietnam, but also creation of evidence worldwide and building of medical research resources to Japan, we investigated obstetric management and gynecological rare tumor in Vietnam at several facilities in Vietnam. In the present study, several findings, which are related to improvement of mothers and children's prognosis,were gained. First, Pregnancy with dengue fever causes thrombocytopenia, which is at risk of postpartum hemorrhage. Second, cesarean section scar pregnancy with an increase in cesarean section rate in Vietnam, could be managed by medication for only selected patients. Third, evaluation of cardiac function by ultrasound examination for fetal growth restriction would be beneficial. Lastly, we found that there was a high secondary rate after molar pregnancy in Vietnam and preventive measures might improve it.

Academic Significance and Societal Importance of the Research Achievements

デング熱は日本においても散発例が報告されており(妊婦発症は未)、グローバル化が進む現在、これらの知見は将来日本で診療が必要となった際に貴重な情報となる可能性がある。また、日本においては妊婦の重症例に対する集学的医療が進められているが、一方で高コストや侵襲性が高いなどの問題点もある。今回の帝切創部妊娠の内科的治療の検討は症例によっては考慮されることが明らかとなった。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (27 results)

All 2020 2019 2018 2017 Other

All Int'l Joint Research (4 results) Journal Article (17 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 15 results,  Open Access: 4 results) Presentation (6 results) (of which Invited: 2 results)

  • [Int'l Joint Research] フエ医科薬科大学/Tu Du 病院(ベトナム)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] フエ医科薬科大学/Tu Du 病院(ベトナム)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Tu Du 病院/Vinh Long病院(ベトナム)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2015 Annual Research Report
  • [Journal Article] The Efficacy and Toxicity of 4-day Chemotherapy With Methotrexate, Etoposide and Actinomycin D in Patients With Choriocarcinoma and High-Risk Gestational Trophoblastic Neoplasia2020

    • Author(s)
      Sato S, Yamamoto E, Niimi K, Ino K, Nishino K, Suzuki S, Kotani T, Kajiyama H, Kikkawa F.
    • Journal Title

      Int J Clin Oncol

      Volume: 25 Issue: 1 Pages: 203-209

    • DOI

      10.1007/s10147-019-01540-9

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 周産期感染症 梅毒,GBS,その他(解説)2019

    • Author(s)
      小谷友美
    • Journal Title

      日本産科婦人科学会雑誌

      Volume: 71 Pages: 2430-2434

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Adverse effects of endometriosis on pregnancy: a case-control study2019

    • Author(s)
      Miura Mayo、Ushida Takafumi、Imai Kenji、Wang Jingwen、Moriyama Yoshinori、Nakano-Kobayashi Tomoko、Osuka Satoko、Kikkawa Fumitaka、Kotani Tomomi
    • Journal Title

      BMC Pregnancy and Childbirth

      Volume: 19 Issue: 1 Pages: 373-373

    • DOI

      10.1186/s12884-019-2514-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Endometriosis and cancer.2019

    • Author(s)
      Kajiyama H, Suzuki S, Yoshihara M, Tamauchi S, Yoshikawa N, Niimi K, Shibata K, Kikkawa F.
    • Journal Title

      Free Radic Biol Med.

      Volume: 133 Pages: 186-192

    • DOI

      10.1016/j.freeradbiomed.2018.12.015

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical Significance of Ubiquitin-associated Protein 2-like in Patients With Uterine Cervical Cancer2019

    • Author(s)
      YOSHIDA KOSUKE、KAJIYAMA HIROAKI、INAMI ERI、TAMAUCHI SATOSHI、IKEDA YOSHIKI、YOSHIKAWA NOBUHISA、NISHINO KIMIHIRO、UTSUMI FUMI、NIIMI KAORU、SUZUKI SHIRO、SHIBATA KIYOSUMI、NAWA AKIHIRO、KIKKAWA FUMITAKA
    • Journal Title

      In Vivo

      Volume: 34 Issue: 1 Pages: 109-116

    • DOI

      10.21873/invivo.11751

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fertility-sparing surgery and oncologic outcome among patients with early-stage ovarian cancer ~propensity score- matched analysis~2019

    • Author(s)
      Kajiyama Hiroaki、Suzuki Shiro、Yoshikawa Nobuhisa、Kawai Michiyasu、Mizuno Kimio、Yamamuro Osamu、Nagasaka Tetsuro、Shibata Kiyosumi、Kikkawa Fumitaka
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 1235-1235

    • DOI

      10.1186/s12885-019-6432-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic factors and effects of fertility-sparing surgery in women of reproductive age with ovarian clear-cell carcinoma: a propensity score analysis2019

    • Author(s)
      Yoshihara Masato、Kajiyama Hiroaki、Tamauchi Satoshi、Suzuki Shiro、Takahashi Kunihiko、Matsui Shigeyuki、Kikkawa Fumitaka
    • Journal Title

      Journal of Gynecologic Oncology

      Volume: 30 Issue: 6

    • DOI

      10.3802/jgo.2019.30.e102

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unique miRNA profiling of squamous cell carcinoma arising from ovarian mature teratoma: comprehensive miRNA sequence analysis of its molecular background2019

    • Author(s)
      Yoshida Kosuke、Yokoi Akira、Kagawa Takumi、Oda Shingo、Hattori Satomi、Tamauchi Satoshi、Ikeda Yoshiki、Yoshikawa Nobuhisa、Nishino Kimihiro、Utsumi Fumi、Niimi Kaoru、Suzuki Shiro、Shibata Kiyosumi、Kajiyama Hiroaki、Yokoi Tsuyoshi、Kikkawa Fumitaka
    • Journal Title

      Carcinogenesis

      Volume: 40 Pages: 1435-1444

    • DOI

      10.1093/carcin/bgz135

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Feasibility of using a handheld tissue hardness meter to quantify uterine contractions and its clinical application for obstetric bleeding management2019

    • Author(s)
      Imai Kenji、Kotani Tomomi、Ushida Takafumi、Moriyama Yoshinori、Nakano Tomoko、Kikkawa Fumitaka
    • Journal Title

      Journal of Obstetrics and Gynaecology

      Volume: 39 Issue: 6 Pages: 757-762

    • DOI

      10.1080/01443615.2019.1581748

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Possible Association between Cathepsin V and the Development of Placenta Accreta Spectrum Disorde2019

    • Author(s)
      Matsukawa S, Sumigama S, Kotani T, Wang J, Miki R, Moriyama Y, Nakano T, Mano Y, Tsuda H, Tamakoshi K, Kikkawa F
    • Journal Title

      Gynecol Obstet Invest

      Volume: 印刷中 Issue: 4 Pages: 396-406

    • DOI

      10.1159/000496609

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Survival impact of capsule status in stage I ovarian mucinous carcinoma-A mulicentric retrospective study.2019

    • Author(s)
      Kajiyama H, Suzuki S, Yoshikawa N, Kawai M, Nagasaka T, Kikkawa F.
    • Journal Title

      Eur J Obstet Gynecol Reprod Biol.

      Volume: 印刷中 Pages: 131-136

    • DOI

      10.1016/j.ejogrb.2019.01.009

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dengue fever during pregnancy2018

    • Author(s)
      Tien Dat T, Kotani T, Yamamoto E, Shibata K, Moriyama Y, Tsuda H, Yamashita M, Kajiyama H, Duc Thien Minh D, Quang Thanh L, Kikkawa F
    • Journal Title

      Nagoya Journal of Medical Science

      Volume: 80 Issue: 2 Pages: 241-247

    • DOI

      10.18999/nagjms.80.2.241

    • NAID

      120006469003

    • ISSN
      2186-3326
    • URL

      https://nagoya.repo.nii.ac.jp/records/26021

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Maternal protein S activity is associated with massive hemorrhage during caesarean section: retrospective case-control study2018

    • Author(s)
      Imai Kenji、Kotani Tomomi、Nakano Tomoko、Ushida Takafumi、Hirakawa Akihiro、Kikkawa Fumitaka
    • Journal Title

      The Journal of Maternal-Fetal & Neonatal Medicine

      Volume: 9 Issue: 16 Pages: 1-5

    • DOI

      10.1080/14767058.2018.1443067

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of serum asymmetric dimethylarginine, homocysteine, and l -arginine concentrations during early pregnancy with hypertensive disorders of pregnancy2017

    • Author(s)
      Maruta Ei、Wang Jingwen、Kotani Tomomi、Tsuda Hiroyuki、Nakano Tomoko、Imai Kenji、Sumigama Seiji、Niwa Yoshimitsu、Mitsui Takashi、Yoshida Shigeru、Yamashita Mamoru、Nawa Akihiro、Tamakoshi Koji、Kajiyama Hiroaki、Kikkawa Fumitaka
    • Journal Title

      Clinica Chimica Acta

      Volume: 475 Pages: 70-77

    • DOI

      10.1016/j.cca.2017.10.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spontaneous regression of gestational trophoblastic neoplasia2017

    • Author(s)
      Niimi K, Yamamoto E, Nishino K, Fujiwara S, Ino K, Kikkawa F
    • Journal Title

      Gynecol Oncol Rep

      Volume: 21 Pages: 98-100

    • DOI

      10.1016/j.gore.2017.07.011

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simulation training is useful for shortening the decision-to-delivery interval in cases of emergent cesarean section2017

    • Author(s)
      Iitani Yukako、Tsuda Hiroyuki、Ito Yumiko、Moriyama Yoshinori、Nakano Tomoko、Imai Kenji、Kotani Tomomi、Kikkawa Fumitaka
    • Journal Title

      The Journal of Maternal-Fetal & Neonatal Medicine

      Volume: ‐ Issue: 23 Pages: 1-5

    • DOI

      10.1080/14767058.2017.1365126

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment and characterization of cell lines derived from complete hydatidiform mole2017

    • Author(s)
      Yamamoto Eiko、Niimi Kaoru、Kiyono Tohru、Yamamoto Toshimichi、Nishino Kimihiro、Nakamura Kenichi、Kotani Tomomi、Kajiyama Hiroaki、Shibata Kiyosumi、Kikkawa Fumitaka
    • Journal Title

      International Journal of Molecular Medicine

      Volume: 40 Issue: 3 Pages: 614-622

    • DOI

      10.3892/ijmm.2017.3067

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 周産期感染症 梅毒,GBS,その他2019

    • Author(s)
      小谷友美
    • Organizer
      第71回日本産科婦人科学会学術講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 生涯研修プログラム3:周産期感染症 梅毒,GBS,その他2019

    • Author(s)
      小谷友美
    • Organizer
      第71回日本産科婦人科学会学術講演会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 絨毛癌細胞におけるNK細胞を介した免疫逃避機構に対する糖転移酵素C2GnTの役割2017

    • Author(s)
      中村謙一、新美薫、山本英子、佐藤静香、関谷陽子、吉川史隆
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 絨毛癌に対するModified MEA療法の有用性について2017

    • Author(s)
      佐藤静香、新美薫、中村謙一、西野公博、山本英子、吉川史隆
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 子宮動脈塞栓術後妊娠における周産期合併症の検討2017

    • Author(s)
      野元正崇、小谷友美、森山佳則、飯谷友佳子、三浦麻世、伊藤由美子、平光志麻、澤田雅子、今井健史、中野知子、津田弘之、吉川史隆
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 造影超音波検査を用いた産後過多出血の新規予測法に関する検討2017

    • Author(s)
      今井健史、小谷友美、野元正崇、飯谷友佳子、三浦麻世、伊藤由美子、森山佳則、平光志麻、澤田雅子、中野知子、津田弘之、吉川史隆
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Related Report
      2017 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2022-11-04  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi