| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2017: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
We could construct the proposed systems as planned, which can map genetic variations onto protein structures, and the results are available through the web site called snvmap. For the purpose, we generated model structures of human proteins, if they are not available in PDB.
By using the mapping results, we performed statistical analyses and found some interesting rare variations related with the metabolism of oseltamivir, an anti-virus drug, which specific for east Asian populations.
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