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Development of next-generation MRI technology for microstructure tomography

Research Project

Project/Area Number 15H02777
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Life / Health / Medical informatics
Research InstitutionUniversity of Toyama

Principal Investigator

Hirobayashi Shigeki  富山大学, 大学院理工学研究部(工学), 教授 (40272950)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Keywordsソフトウエア学 / 断層撮影技術 / MRI / 情報工学
Outline of Final Research Achievements

In this study, we applied a high-precision analysis method of NHA to MRI. In experiment, we placed multi objects in micro space, and MRI measurement data assuming the ideal environment was created by computer simulation. The created MRI measurement data is analyzed by each method; FFT commonly used for MRI image reconstruction, interpolation method, NHA. MRI images were reconstructed and compared based on the analysis results of each method. From the experimental results, in the MRI image by FFT and interpolation method, the resolution was insufficient, and due to side lobe interference, it has not been possible to separate and represent a multi objects. On the other hand, in the MRI image by NHA, the occurrence of side lobes was greatly suppressed by accurately analyzing the measurement data, and NHA can visualized space of less than 100 μm. From above results, there is possibility of ultra-high resolution MRI using NHA.

Academic Significance and Societal Importance of the Research Achievements

MRIは、仮想的に断層撮影を行うために、内部で主に2次元FFTを用いて画像を再構成している。このFFTに代わって、2次元NHAを応用することで、既存のハードウェアの性能を極限まで高め、低磁場でこれまで以上の空間分解能を実現できる可能性を示した。

Report

(4 results)
  • 2018 Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (3 results)

All 2018 2016

All Journal Article (2 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Multiwindow Nonharmonic Analysis Method for Gravitational Waves2018

    • Author(s)
      Dongbao Jia, Kenta Yanagisawa, Yuta Ono, Kanna Hirobayashi, Masaya Hasegawa, Shigeki Hirobayashi, Hideyuki Tagoshi, Tatsuya Narikawa, Nami Uchikata, Hirotaka Takahashi
    • Journal Title

      IEEE Access

      Volume: Vol.6 No.1 Pages: 48645-48655

    • DOI

      10.1109/access.2018.2867494

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Time-frequency-based non-harmonic analysis to reduce line-noise impact for LIGO observation system2018

    • Author(s)
      Dongbao Jia, Kenta Yanagisawa, Masaya Hasegawa, Shigeki Hirobayashi, Hideyuki Tagoshi, Tatsuya Narikawa, Nami Uchikata, Hirotaka Takahashi
    • Journal Title

      Astronomy and Computing

      Volume: Vol.25 Pages: 238-246

    • DOI

      10.1016/j.ascom.2018.10.003

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Visualization of microvascular that assumes an ultra-high field MRI with high precision frequency analysis2016

    • Author(s)
      Masaya Hasegawa, Shigeki Hirobayashi
    • Organizer
      ITME 2016
    • Place of Presentation
      Fuzhou, China
    • Year and Date
      2016-12-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research

URL: 

Published: 2015-04-16   Modified: 2020-03-30  

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