| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2017: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Outline of Final Research Achievements |
In this study, dynamic gels were designed using biomolecular complexes and photo-dimerization as dynamic cross-links, and spatiotemporally controllable medical systems were developed using their gels. Dynamic gels with model drugs as dynamic cross-links regulated the drug release by the conformational change of the gel networks. Dynamic gels with molecular recognition sites were formed on gold sensor chips, enabling us to detect a target biomolecule sensitively and selectively. Biomolecule- and photo-responsive dynamic gels were strategically designed as smart scaffolds for regulating cell behavior.
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