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Magnetic particle imaging system with fast data acquisition and high image resolution

Research Project

Project/Area Number 15H03038
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionMeiji University

Principal Investigator

Ishihara Yasutoshi  明治大学, 理工学部, 専任教授 (00377219)

Research Collaborator TAKAGI Tomoyuki  
HATSUDA Tomoki  
ARAYAMA Masahiro  
MATSUHISA Akihiro  
URUSHIBATA Satoshi  
KUZUHARA Ayane  
FUJITA Hiromitsu  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2017: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Keywords画像診断装置 / 磁性ナノ粒子 / イメージング / MPI / 磁性ナノ粒子イメージング / 画像再構成 / 特異値分解 / 医用工学 / 計測工学 / 画像工学 / 画像診断システム / 計測 / 医用システム
Outline of Final Research Achievements

Diagnosing cancers and cardiovascular diseases at an early stage by magnetic particle imaging (MPI) has been expected. In MPI, however, strong gradient magnetic field strength is needed to obtain high image resolution. In this study, the new algorithm that can make image reconstruction of the image data acquired fast with high image resolution was proposed. The validity of the image reconstruction method was evaluated by numerical analysis, and satisfactory image quality was obtained compared with the conventional method. In addition, the two-dimensional MPI system was constructed and validity of the proposed image reconstruction method was clarified experimentally. Furthermore, the new signal acquisition method for detecting a magnetization signal by vibrating a magnetic nanoparticle without using an alternating current magnetic field was proposed, and the feasibility was shown.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (14 results)

All 2017 2016 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (11 results) (of which Int'l Joint Research: 5 results) Remarks (1 results)

  • [Journal Article] Basic study of image reconstruction method using neural networks with additional learning for magnetic particle imaging2016

    • Author(s)
      T. Hatsuda, T. Takagi, A. Matsuhisa, M. Arayama, H. Tsuchiya, S. Takahashi, Y. Ishihara
    • Journal Title

      International Journal on Magnetic Particle Imaging

      Volume: 2

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Image Reconstruction Method Using Orthonormal Basis by Singular Value Decomposition for Magnetic Particle Imaging2015

    • Author(s)
      高木智幸、土屋寛貴、初田朋希、石原康利
    • Journal Title

      Transactions of Japanese Society for Medical and Biological Engineering

      Volume: 53 Issue: 5 Pages: 276-282

    • DOI

      10.11239/jsmbe.53.276

    • NAID

      130005128622

    • ISSN
      1347-443X, 1881-4379
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Improvement of Detection Sensitivity for MPI System Based on Vibrating Particles2017

    • Author(s)
      S. Urushibata, T. Takagi, T. Hatsuda, A. Matsuhisa, M. Arayama, Y. Ishihara
    • Organizer
      International Workshop on Magnetic Particle Imaging 2017
    • Place of Presentation
      Prague
    • Year and Date
      2017-03-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ニューラルネットワークを用いた磁性ナノ粒子イメージングの高分解能化2017

    • Author(s)
      藤田浩充、石原康利
    • Organizer
      生体医工学シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 磁性ナノ粒子イメージングにおける磁性ナノ粒子の能動振動を用いた SN 比の改善2017

    • Author(s)
      漆畑智士、石原康利
    • Organizer
      日本設計工学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Evaluation of Magnetic Field Strength for FFP Line Scanning Driven by Low Electric Currents2017

    • Author(s)
      A. Kuzuhara, T. Hatsuda, T. Takagi, S. Takahashi, M. Arayama, Y. Ishihara
    • Organizer
      International Workshop on Magnetic Particle Imaging 2016
    • Place of Presentation
      Prague
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 特異値分解を用いた磁性ナノ粒子イメージングのノイズ耐性改善2016

    • Author(s)
      高木智幸、土屋寛貴、初田朋希、石原康利
    • Organizer
      生体医工学シンポジウム2016
    • Place of Presentation
      旭川
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] A basic study of an image reconstruction method using neural networks with additional learning for magnetic particle imaging2016

    • Author(s)
      T. Hatsuda, T. Takagi, A. Matsuhisa, M. Arayama, H. Tsuchiya, Y. Ishihara
    • Organizer
      International Workshop on Magnetic Particle Imaging 2016
    • Place of Presentation
      Lubeck
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Magnetic signal separation using independent component analysis2016

    • Author(s)
      M. Arayama, T. Takagi, T. Hatsuda, A. Matsuhisa, Y. Ishihara
    • Organizer
      International Workshop on Magnetic Particle Imaging 2016
    • Place of Presentation
      Lubeck
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Magnetic signal detection method based on active vibration of magnetic nanoparticles2016

    • Author(s)
      A. Matsuhisa, T. Hatsuda, T. Takagi, M. Arayama, Y. Ishihara
    • Organizer
      International Workshop on Magnetic Particle Imaging 2016
    • Place of Presentation
      Lubeck
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 磁性ナノ粒子イメージングにおける特異値直交基底を用いた画像再構成法2015

    • Author(s)
      高木智幸、土屋寛貴、初田朋希、石原康利
    • Organizer
      日本生体医工学会関東支部若手研究者発表会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 磁性ナノ粒子イメージングにおけるニューラルネットワークを用いた画像再構成法に関する基礎検討2015

    • Author(s)
      初田朋希、土屋寛貴、高木智幸、石原康利
    • Organizer
      生体医工学シンポジウム2015
    • Place of Presentation
      岡山
    • Year and Date
      2015-09-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] 特異値分解による直交基底を用いた磁性ナノ粒子イメージングにおける逆問題再構成手法の検討2015

    • Author(s)
      高木智幸、土屋寛貴、初田朋希、石原康利
    • Organizer
      生体医工学シンポジウム2015
    • Place of Presentation
      岡山
    • Year and Date
      2015-09-25
    • Related Report
      2015 Annual Research Report
  • [Remarks] 計測工学研究室(石原研) 明治大学理工学部

    • URL

      http://www.isc.meiji.ac.jp/~insteng/

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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