Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2017: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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Outline of Final Research Achievements |
For the people with physical disabilities, the maintenance of body weight by physical exercise is difficult. In the current study we aimed to reveal the relation between immobilized limb and systemic metabolism. The mouse model of spinal cord injury showed deterioration in glucose tolerance. In addition, we found that the inflammatory reaction occurs within the immobilized muscles though the activation of macrophages. Our results suggest that the mobilization of disabled muscle, even by passively, may provide benefit for physical fitness control for those patients.
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