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Development of the strategy to control obesity among people with physical disabilities.

Research Project

Project/Area Number 15H03048
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNational Rehabilitation Center for Persons with Disabilities

Principal Investigator

Akai Masami  国立障害者リハビリテーションセンター(研究所), 研究所, 研究所顧問 (80143452)

Co-Investigator(Kenkyū-buntansha) 緒方 徹  国立障害者リハビリテーションセンター(研究所), その他部局等, 障害者健康増進・運動医科学支援センター長 (00392192)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2017: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Keywords慢性炎症 / 二次障害 / 耐糖能異常
Outline of Final Research Achievements

For the people with physical disabilities, the maintenance of body weight by physical exercise is difficult. In the current study we aimed to reveal the relation between immobilized limb and systemic metabolism. The mouse model of spinal cord injury showed deterioration in glucose tolerance. In addition, we found that the inflammatory reaction occurs within the immobilized muscles though the activation of macrophages. Our results suggest that the mobilization of disabled muscle, even by passively, may provide benefit for physical fitness control for those patients.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (2 results)

All 2017

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] Oligodendrocyte Progenitor Cells Directly Utilize Lactate for Promoting Cell Cycling and Differentiation2017

    • Author(s)
      Ichihara Y, Doi T, Ryu Y, Nagao M, Sawada Y, Ogata T
    • Journal Title

      J Cell Physiol

      Volume: 232 Issue: 5 Pages: 986-995

    • DOI

      10.1002/jcp.25690

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The swimming test is effective for evaluating spasticity after contusive spinal cord injury2017

    • Author(s)
      Ryu Y, Ogata T, Nagao M, Kitamura T, Morioka K, Ichihara Y, Doi T, Sawada Y, Akai M, Nishimura R, Fujita N
    • Journal Title

      PLoS One

      Volume: 12 Issue: 2 Pages: e0171937-e0171937

    • DOI

      10.1371/journal.pone.0171937

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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