| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2015: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Outline of Final Research Achievements |
In this study, we have developed electrophoresis technique using supramolecular hydrogels, which formed by self-assembly of low molecular weight hydrogelator, as a novel separation and analysis method for biopolymers such as proteins and nucleic acids. In the electrophoresis of the denatured proteins, it was revealed that the separation manners were changed by the concentration of the ionic surfactant. Large DNA samples, which generally need pulse field gel electrophoresis to separate, could be separated by a common submarine electrophoresis apparatus by using a supramolecular hydrogel as a matrix. We also achieved the development of new low molecular weight hydrogelator, which are expected to function as a new matrix of electrophoresis for biopolymers.
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