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Recognition and reduction of modern water pollutions using 3D stationary phase having cell membrane functions

Research Project

Project/Area Number 15H03846
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Green/Environmental chemistry
Research InstitutionKyoto Prefectural University

Principal Investigator

Hosoya Ken  京都府立大学, 生命環境科学研究科, 教授 (00209248)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Keywords汚染除去材料 / HPLC / 3D固相 / 表面修飾 / MPC / 細胞機能 / 血液評価 / スプレー法 / HPLC / 3D固相 / MPC / 3D固相
Outline of Final Research Achievements

The purpose of this study is to construct a pseudo-cell membrane layer that captures pharmaceutical and personal care products (PPCP) from the aqueous phase, 2) Create a pseudo-hydrophilic interaction separation layer capable of fully retaining captured PPCP, 3) Recognizing the characteristics of PPCP,
A multidimensional mechanism to eliminate contaminants is to construct a molecular template layer. After three years of study, we succeeded in capturing concentration and quantification from the actual river water of sulpiride, the final purpose of this study, and completed the research purpose. This result has been confirmed to be effective for compounds such as shellfish poison, saxitoxin, and domoic acid, which have recently been a problem, not only the sulpiride used as a model, and has become a result of the developments.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (9 results)

All 2017 2016 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Effect of Solvents on the Surface Modification of Hydrophilic Macro-Porous Particles with an Ion-Exchange Monomer Having Both Anion and Cation Exchange Groups2016

    • Author(s)
      K. Shibata, T. Tanigawa, H. Ito, T. Kubo, and K. Hosoya,
    • Journal Title

      CHROMATOGRAPHY

      Volume: 37 Issue: 3 Pages: 99-104

    • DOI

      10.15583/jpchrom.2016.004

    • NAID

      130005277409

    • ISSN
      1342-8284, 1348-3315
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Molecularly Imprinted Polymers for Selective Adsorption of Lysozyme and Cytochrome c Using a PEG-Based Hydrogel: Selective Recognition for Different Conformations due to pH Conditions2015

    • Author(s)
      Kubo, T.; Arimura, S.; Tominaga, Y.; Naito, T.; Hosoya, K.; Otsuka, K.
    • Journal Title

      Macromolecules

      Volume: 48 Issue: 12 Pages: 4081-4087

    • DOI

      10.1021/acs.macromol.5b00834

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] 血球分離膜の開発2017

    • Author(s)
      古川真由,柴田佳那美,細矢 憲
    • Organizer
      第28回クロマトグラフィー科学会議
    • Related Report
      2017 Annual Research Report
  • [Presentation] イオン交換基の働きで血液を分ける2016

    • Author(s)
      柴田 佳那美,古川麻由,関豊光,細矢憲
    • Organizer
      第27回クロマトグラフィー科学会議
    • Place of Presentation
      慶応義塾大学薬学部(東京都港区)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] マイクロ球状粒子のクロマトグラフィー特性基礎検討2016

    • Author(s)
      谷川 哲也,上本英雄,永田智浩,細矢憲
    • Organizer
      第27回クロマトグラフィー科学会議
    • Place of Presentation
      慶応義塾大学薬学部(東京都港区)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] イオン交換基の働き方を制御する2015

    • Author(s)
      柴田佳那美,関 豊光,伊東晴香,細矢 憲
    • Organizer
      第26回クロマトグラフィー科学会議
    • Place of Presentation
      九州大学医学系キャンパスコラボステーション
    • Year and Date
      2015-11-11
    • Related Report
      2015 Annual Research Report
  • [Book] 化学の基本シリーズ2 有機化学2017

    • Author(s)
      久保拓也,細矢 憲
    • Total Pages
      153
    • Publisher
      化学同人
    • ISBN
      9784759818451
    • Related Report
      2017 Annual Research Report
  • [Remarks] 最優秀発表賞の受賞について(京都府立大学HP)

    • URL

      http://www.kpu.ac.jp/contents_detail.php?co=ser&frmId=5436

    • Related Report
      2016 Annual Research Report
  • [Remarks] 学会賞等の受賞

    • URL

      http://www2.kpu.ac.jp/life_environ/poly_mat_design/index.html

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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