| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
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| Outline of Final Research Achievements |
Using in vitro and computer modeling from biomechanical viewpoints, we investigated the blood flow mechanism in network microchannel that ranges from single blood cell’s motion and deformation, motions of an assemblage of blood cells, and up to blood flow in entire network channel. We clarified that mechanical properties of a red blood cell from membrane’s viscoelasticity play an important role in motion and deformation in shear flow. We also demonstrated that in a network microchannel, a blood flow at bifurcation was determined by interaction between flow rate distribution at the bifurcation and flows in the surrounding channels. These points are considered important in acute failure of microcirculation.
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