• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Evaluation of human iPSCs by incomplete reprogramming and genome instability

Research Project

Project/Area Number 15H04278
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurochemistry/Neuropharmacology
Research InstitutionAichi Medical University

Principal Investigator

Okada Yohei  愛知医科大学, 医学部, 准教授 (30383714)

Co-Investigator(Renkei-kenkyūsha) OKANO HIDEYUKI  慶應義塾大学, 医学部, 教授 (60160694)
MIYA FUYUKI  東京医科歯科大学, 医学部, 助教 (50415311)
IKADA EIJI  山口大学, 医学部, 教授 (30232177)
YASUDA MUNEYOSHI  愛知医科大学, 医学部, 准教授 (10440752)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2017: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2016: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2015: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
KeywordsヒトiPS細胞 / 造腫瘍性 / ゲノム不安定性 / 不完全なリプログラミング
Outline of Final Research Achievements

Induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine and in vitro modeling of human diseases. To overcome their abnormal differentiation and tumorigenicity, the method to evaluate bona fide “appropriately reprogrammed human iPSCs” has been expected. In this study, by focusing on the differences of the tumorigeniticy (glioma-like tumor formation) among human iPSC clones caused by the incomplete reprogramming and genomic instability, we identified reprogramming recalcitrant genes as “Score card”, and examined their applicability to the evaluation of human iPSCs.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (57 results)

All 2018 2017 2016 2015

All Journal Article (14 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 11 results,  Open Access: 10 results,  Acknowledgement Compliant: 3 results) Presentation (41 results) (of which Int'l Joint Research: 7 results,  Invited: 11 results) Book (2 results)

  • [Journal Article] 疾患特異的iPS細胞を用いた神経変性疾患の病態解析・創薬研究2018

    • Author(s)
      岡田洋平、祖父江元
    • Journal Title

      Clinical Neuroscience

      Volume: 36 Pages: 328-332

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Correlation of insulin resistance and motor function in spinal and bulbar muscular atrophy.2017

    • Author(s)
      Nakatsuji H, Araki A, Hashizume A, Hijikata Y, Yamada S, Inagaki T, Suzuki K, Banno H, Suga N, Okada Y, Ohyama M, Nakagawa T, Kishida K, Funahashi T, Shimomura I, Okano H, Katsuno M, Sobue G.
    • Journal Title

      J Neurol.

      Volume: in press Issue: 5 Pages: 839-847

    • DOI

      10.1007/s00415-017-8405-3

    • NAID

      120006331845

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Teratoma Formation Assay for Assessing Pluripotency and Tumorigenicity of Pluripotent Stem Cells2017

    • Author(s)
      Miyawaki Shingo、Okada Yohei、Okano Hideyuki、Miura Kyoko
    • Journal Title

      BIO-PROTOCOL

      Volume: 7 Issue: 16

    • DOI

      10.21769/bioprotoc.2518

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 難治性神経変性疾患における治療開発~患特異的iPS細胞を用いた神経疾患モデルの構築と治療薬の開発2017

    • Author(s)
      岡田洋平、祖父江元
    • Journal Title

      トランスレーショナルリサーチを支援する遺伝子医学MOOK

      Volume: 32 Pages: 110-116

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Altered tau isoform ratio caused by loss of Fus and Sfpq function leads to FTLD-like phenotypes2017

    • Author(s)
      Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno H, Sobue G.
    • Journal Title

      Cell Reports

      Volume: 18 Issue: 5 Pages: 1118-1131

    • DOI

      10.1016/j.celrep.2017.01.013

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016

    • Author(s)
      Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
    • Journal Title

      Stem Cell Reports

      Volume: 6 Issue: 4 Pages: 496-510

    • DOI

      10.1016/j.stemcr.2016.02.011

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tumour resistance in induced pluripotent stem cells derived from naked mole-rats2016

    • Author(s)
      Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Yoshihiro Tsuchiya, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, Ikeda E, Okanoya K, Seino K, Saya H, Okano H & Miura K
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 11471-11471

    • DOI

      10.1038/ncomms11471

    • NAID

      120006535074

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Analysis of induced pluripotent stem cells carrying 22q11.2 deletion2016

    • Author(s)
      Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, Iwayama Y, Toyota T, Matsumoto T, Itasaka N, Sugiyama S, Tanaka M, Yano M, Dean B, Okano H, Yoshikawa T
    • Journal Title

      Translational Psychiatry

      Volume: 6 Issue: 11 Pages: e934-e934

    • DOI

      10.1038/tp.2016.206

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Tumour resistance in induced pluripotent stem cells derived from naked mole-rats2016

    • Author(s)
      Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, Koya I, Okada Y, Kimura T, Tsuchiya Y, Suzuki S, Onishi N, Kuzumaki N, Matsuzaki Y, Narita M, Ikeda E, Okanoya K, Seino K, Saya H, Okano H, Miura K.
    • Journal Title

      Nat. Commun.

      Volume: in press

    • NAID

      120006535074

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] iPS細胞を用いた認知症モデル2016

    • Author(s)
      小野寺一成、岡田洋平
    • Journal Title

      最新医学

      Volume: 71 Pages: 563-569

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage2015

    • Author(s)
      Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano H
    • Journal Title

      Mol Brain

      Volume: 8 Issue: 1 Pages: 31-31

    • DOI

      10.1186/s13041-015-0121-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway2015

    • Author(s)
      Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H
    • Journal Title

      Human Molecular Genetics

      Volume: 24(17) Issue: 17 Pages: 4879-4900

    • DOI

      10.1093/hmg/ddv212

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism.2015

    • Author(s)
      Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 16239-16239

    • DOI

      10.1038/srep16239

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.2015

    • Author(s)
      Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H, Okada Y
    • Journal Title

      Mol Brain

      Volume: 8 Issue: 1 Pages: 79-93

    • DOI

      10.1186/s13041-015-0172-4

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 疾患特異的iPS細胞を用いた神経変性疾患の早期病態の解析2018

    • Author(s)
      岡田洋平、小野寺一成、伊藤卓治、岡田梨奈、勝野雅央、道勇学、祖父江元、岡野栄之
    • Organizer
      新学術領域「脳たんぱく質老化と認知症制御」第7回班員会議
    • Related Report
      2017 Annual Research Report
  • [Presentation] Pathophysiological analysis of spinal-bulbar muscular atrophy using disease specific iPSCs (シンポジウム)2017

    • Author(s)
      Okada Y, Onodera K,Ito T, Shimojo D, Ishihara Y, Tanaka S, Katsuno M,Doyu M,Sobue G,Okano H
    • Organizer
      Society for Neuroscience Annual Meeting, Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 疾患特異的iPS細胞を用いた球脊髄性筋萎縮症の病態解析と新規治療法の開発研究 (招待講演)2017

    • Author(s)
      岡田洋平
    • Organizer
      愛知県特定疾患研究協議会、平成29年度難病教育講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 疾患特異的iPS細胞を用いた神経変性疾患の早期病態の解明2017

    • Author(s)
      岡田洋平、小野寺一成、伊藤卓治、李家?、岡田梨奈、勝野雅央、道勇学、祖父江元、岡野栄之
    • Organizer
      新学術領域「脳たんぱく質老化と認知症制御」第6回班員会議
    • Related Report
      2017 Annual Research Report
  • [Presentation] iPS細胞を用いた神経筋接合部可視化システムの構築2017

    • Author(s)
      伊藤卓治、田中智史、下門大祐、道勇学、岡野栄之、岡田洋平
    • Organizer
      新学術領域「脳たんぱく質老化と認知症制御」第6回班員会議
    • Related Report
      2017 Annual Research Report
  • [Presentation] 疾患特異的iPS細胞を用いた球脊髄性筋萎縮症(SBMA)の病態解析2017

    • Author(s)
      小野寺一成、下門大祐、石原康晴、道勇学、勝野雅央、祖父江元、岡野栄之、岡田洋平
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 神経筋接合部のライブセルイメージング2017

    • Author(s)
      伊藤卓治、田中智史、下門大祐、道勇学、岡野栄之、岡田洋平
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ゲノム編集を用いた骨格筋における球脊髄性筋萎縮症(SBMA)の病態解析2017

    • Author(s)
      田中智史、伊藤卓治、太田明伸、曽根岳史、下門大祐、今釜史郎、細川好孝、道勇学、岡野栄之、岡田洋平
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ヒトiPS細胞由来運動神経細胞移植による末梢神経における運動機能の再建2017

    • Author(s)
      丹羽智史、新海宏明、小野寺一成、伊藤卓司、田中智史、李家?、栗本秀、中野智則、道勇学、平田仁、岡田洋平
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 低酸素がヒトiPS細胞由来神経系前駆細胞の分化成熟に与える影響2017

    • Author(s)
      岡田洋平、李家イ、岡田梨奈、小野寺一成、伊藤卓司、岡野ジェイムズ洋尚、勝野雅央、道勇学、岡野栄之、祖父江元
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The analysis of neuromuscular pathology of spinal-bulbar muscular atrophy using iPSC-derived disease model2017

    • Author(s)
      Okada Y, Ito T, Tanaka T, DShimojo D, Onodera K, Katsuno M, Okano H, Sobue G, Doyu D
    • Organizer
      第23回世界神経学会議・第58回日本神経学会学術大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Pathophysiological analysis of spinal and bulbar muscular atrophy using disease-specific iPSCs.2017

    • Author(s)
      Onodera K, Shimojo D, Ishihara Y, Doyu M, Okano H, Katsuno M, Sobue G, Okada Y
    • Organizer
      第23回世界神経学会議・第58回日本神経学会学術大会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Therapeutic approach for neurodegenerative diseases focusing on early pathogenesis and disease accelerating factors using disease specific iPSCs2017

    • Author(s)
      Okada Y, Onodera K, Ito T, Shimojo D, Katsuno M, Doyu M, Sobue G, Okano H
    • Organizer
      新学術領域研究「脳タンパク質老化と認知症制御」第2回国際シンポジウム
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Pathophysiological analysis of skeletal muscles in spinal bulbar muscular atrophy by genome editing of CAG repeats2017

    • Author(s)
      Tanaka S, Ito T, Ota A, Sone T, Shimojo D, Imagama S, Hosokawa Y, Doyu M, Okano H, Okada Y
    • Organizer
      Society for Neuroscience Annual Meeting, Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Establishment of iPSC-derived neuromuscular models for pathological analysis and drug screening2017

    • Author(s)
      Ito T, Tanaka S, Shimojo D, Doyu M, Okano H, Okada Y
    • Organizer
      Society for Neuroscience Annual Meeting, Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] iPS細胞由来神経筋共培養モデルを用いた神経筋疾患の病態解析2017

    • Author(s)
      伊藤卓治、田中智史、下門大祐、道勇学、岡野栄之、岡田洋平
    • Organizer
      第40回日本分子生物学会年会・生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ゲノム編集を用いた球脊髄性筋萎縮症(SBMA)における骨格筋病態の解析2017

    • Author(s)
      田中智史、伊藤卓治、太田明伸、曽根岳史、今釜史郎、細川好孝、岡野栄之、道勇学、岡田洋平
    • Organizer
      第40回日本分子生物学会年会・生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 低酸素がヒトiPS細胞由来神経系前駆細胞の分化成熟に与える影響2017

    • Author(s)
      岡田梨奈、李家イ、小野寺一成、伊藤卓治、勝野雅央、祖父江元、岡野栄之、道勇学、岡野ジェイムズ洋尚、岡田洋平
    • Organizer
      第40回日本分子生物学会年会・生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 疾患特異的iPS細胞を用いた球脊髄性筋萎縮症(SBMA)の病態解析2017

    • Author(s)
      小野寺一成、下門大祐、伊藤卓治、石原康晴、勝野雅央、道勇学、祖父江元、岡野栄之、岡田洋平
    • Organizer
      第40回日本分子生物学会年会・生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 疾患特異的iPS細胞を用いた神経変性疾患の分子病態の解析2017

    • Author(s)
      岡田洋平、小野寺一成、伊藤卓治、下門大祐、道勇学、勝野雅央、祖父江元、岡野栄之
    • Organizer
      新学術領域「脳たんぱく質老化と認知症制御」第5回班員会議
    • Related Report
      2016 Annual Research Report
  • [Presentation] Reconstruction of Denervated Muscles Using Motor Neurons Derived from Mouse ES Cells2017

    • Author(s)
      Shinkai H., Niwa S., Kurimoto S., Okada Y., Hirata H
    • Organizer
      2017 annual meeting - Orthopaedic Research Society
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] iPS細胞を用いた神経再生と神経疾患研究 (招待講演)2016

    • Author(s)
      岡田洋平
    • Organizer
      第二回 中外製薬 研究交流会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] iPS細胞を用いた神経・筋疾患研究(招待講演)2016

    • Author(s)
      岡田洋平
    • Organizer
      第3回 筋ジストロフィー研究会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 疾患特異的iPS細胞を用いた神経変性疾患の分子病態の解析2016

    • Author(s)
      岡田洋平、小野寺一成、下門大祐、伊藤卓治、道勇学、勝野雅央、祖父江元、岡野栄之
    • Organizer
      新学術領域「脳たんぱく質老化と認知症制御」第4回班員会議
    • Related Report
      2016 Annual Research Report
  • [Presentation] Pathophysiological analysis of spinal-bulbar muscular atrophy using disease specific iPSCs2016

    • Author(s)
      Onodera K, Shimojo D, Torii Y, Ishihara Y, Doyu M, Okano H, Katsuno M, Sobue G, Okada Y
    • Organizer
      第57回日本神経学会学術大会
    • Related Report
      2016 Annual Research Report
  • [Presentation] ゲノム編集によるポリグルタミン病の病態解析と治療開発の可能性2016

    • Author(s)
      田中智史、伊藤卓治、太田明伸、曽根岳史、今釜史郎、細川好孝、道勇学、岡野栄之、岡田洋平
    • Organizer
      第1回ゲノム編集学会
    • Related Report
      2016 Annual Research Report
  • [Presentation] ヒトiPS細胞を用いたニューロマスキュラーモデルの構築2016

    • Author(s)
      田中智史、下門大祐、伊藤卓治、今釜史郎、西田佳弘、道勇学、大野欽司、岡野栄之、石黒直樹、岡田洋平
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 遺伝性神経筋疾患に対するCRISPR/Cas9によるゲノム編集治療の可能性2016

    • Author(s)
      田中智史、伊藤卓治、太田明伸、今釜史郎、西田佳弘、細川好孝、道勇学、大野欽司、石黒直樹、岡田洋平
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 低酸素培養がヒトiPS細胞由来神経系前駆細胞の分化成熟に与える影響2016

    • Author(s)
      李家イ、岡田梨奈、小野寺一成、下門大祐、岡野ジェイムズ洋尚、勝野雅央、道勇学、祖父江元、岡野栄之、岡田洋平
    • Organizer
      第39回日本分子生物学会年会
    • Related Report
      2016 Annual Research Report
  • [Presentation] ゲノム編集によるポリグルタミン病の病態解析と治療開発の可能性2016

    • Author(s)
      田中智史、伊藤卓治、太田明伸、曽根岳史、今釜史郎、細川好孝、道勇学、岡野栄之、岡田洋平
    • Organizer
      第39回日本分子生物学会年会
    • Related Report
      2016 Annual Research Report
  • [Presentation] ヒトiPS細胞を用いたニューロマスキュラーイメージング2016

    • Author(s)
      伊藤卓治、田中智史、下門大祐、道勇学、岡野栄之、岡田洋平
    • Organizer
      第39回日本分子生物学会年会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 疾患特異的ヒトiPS細胞を用いた運動ニューロン疾患の病態解析2015

    • Author(s)
      岡田洋平
    • Organizer
      第33回日本神経治療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-11-26
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] iPS細胞を用いた神経再生と神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第21回糖尿病性神経障害を考える会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2015-10-24
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] iPS細胞を用いた神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第2回愛知医科大学糖神合同セミナー
    • Place of Presentation
      長久手
    • Year and Date
      2015-10-20
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] iPS細胞を用いた神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第34回日本認知症学会学術集会
    • Place of Presentation
      青森
    • Year and Date
      2015-10-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ES細胞、iPS細胞を用いた神経再生と神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第12回名古屋脊椎脊髄セミナー2015
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-18
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ヒトiPS細胞の迅速で効率的な神経幹細胞分化誘導法の検討2015

    • Author(s)
      安田宗義、小野寺一成、鳥居由紀子、大須賀浩二、道勇 学、高安正和、岡田洋平
    • Organizer
      第30回日本脊髄外科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-06-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] 多能性幹細胞(ES細胞、iPS細胞)を用いた神経再生と神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第3回横浜神経疾患レクチャー
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-11
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ヒト疾患iPS細胞の可能性2015

    • Author(s)
      岡田洋平
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都
    • Year and Date
      2015-05-28
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] iPS細胞を用いた神経疾患研究2015

    • Author(s)
      岡田洋平
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-05-23
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] An approach for understanding the pathogenesis of SBMA by disease specific iPSCs.2015

    • Author(s)
      小野寺一成、下門大祐、鳥居由紀子、石原康晴、勝野雅央、道勇学、岡野栄之、祖父江元、岡田洋平
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
  • [Book] 神経疾患治療ストラテジー2017

    • Author(s)
      祖父江元、伊藤卓治、岡田洋平、他
    • Total Pages
      451
    • Publisher
      中山書店
    • ISBN
      9784521745435
    • Related Report
      2017 Annual Research Report
  • [Book] アクチュアル脳・神経疾患の臨床「神経疾患治療ストラテジー」2017

    • Author(s)
      伊藤卓治、岡田洋平
    • Total Pages
      451
    • Publisher
      中山書店
    • ISBN
      9784521745435
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi