| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
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| Outline of Final Research Achievements |
Our previous studies have indicated that intracerebroventricular (ICV) administration of several neuropeptides related to feeding regulation affect psychomotor activity in fish. Therefore, we examined the effect of ICV injection of neuropeptides such as cholecystokinin and pituitary adenylate cyclase-activating polypeptide (PACAP) on emotional behavior including anxiety-like behavior in fish. ICV administration of neuropeptides mentioned above induced anxiety-like behavior in fish. In addition, we prepared transgenic fish (including vasotosine, PACAP and mineralocorticoid-receptor knock out fish), and observed swimming behavior. The results suggested that psychomotor activity is affected by hormones- and their receptors-knock out.
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