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Flickering LED light condition having less impact on melatonin secretion

Research Project

Project/Area Number 15H04431
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied anthropology
Research InstitutionFukuoka Women's University (2017-2018)
Kyushu University (2015-2016)

Principal Investigator

Kozaki Tomoaki  福岡女子大学, 国際文理学部, 准教授 (80380715)

Research Collaborator Kusano Yosuke  
Takakura Jun-ya  
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
KeywordsLED / 光 / 点滅 / メラトニン / 瞳孔 / 高速点滅光 / 人間工学
Outline of Final Research Achievements

This study examined characteristic of LED flickering light which have less impact on melatonin secretion. Since our findings in this study, the flickering light could prevent melatonin suppression only under the condition; the frequency of the flickering is under 1000Hz, the light intensity is high, the preventive effect could be get only immediate after the light exposure. On the other hand, the flickering light might suppress melatonin strongly, when the flickering light was exposed for more than one hour and the duty ratio (time ratio of turn the light on and turn it off) is high.

Academic Significance and Societal Importance of the Research Achievements

本研究より、光の色や強さなど視覚的に同じでも知覚されない程度の高速で点滅している場合は、点滅していない場合とは異なるメラトニン分泌抑制作用を持つことが示された。これは、概日リズム系の新たな視細胞であるmRGCが他の視細胞とは光に対する時間応答特性が異なることを示唆する学術的に意義のある結果である。また、夜間照明は概日リズム位相を遅らせ、睡眠問題を引き起こし、抗酸化作用や抗がん作用が指摘されているメラトニン分泌を抑制するなど人間の健康を考える上で問題となっている。そのため、人間に影響の少ないLEDの発光特性を示唆する本研究は健康的な照明環境の普及に貢献する社会的にも意義のある成果である。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (15 results)

All 2018 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (12 results) (of which Int'l Joint Research: 7 results,  Invited: 2 results)

  • [Journal Article] Non-cotton swab sample collection may not affect salivary melatonin assay results2018

    • Author(s)
      Kozaki Tomoaki、Hidaka Yuki
    • Journal Title

      Journal of Physiological Anthropology

      Volume: 37 Issue: 1 Pages: 17-17

    • DOI

      10.1186/s40101-018-0178-6

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Suppression of salivary melatonin secretion under 100-Hz flickering and non-flickering blue light2018

    • Author(s)
      Kozaki Tomoaki、Hidaka Yuki、Takakura Jun-ya、Kusano Yosuke
    • Journal Title

      Journal of Physiological Anthropology

      Volume: 37 Issue: 1 Pages: 23-23

    • DOI

      10.1186/s40101-018-0183-9

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] PUPILLARY RESPONSE UNDER DIFFERENT DUTY RATIO OF 100 Hz FLICKER LIGHT2017

    • Author(s)
      日高勇樹、矢野雅人、高倉潤也、草野洋介、小崎智照
    • Journal Title

      Japanese Journal of Physiological Anthropology

      Volume: 22 Issue: 3 Pages: 129-133

    • DOI

      10.20718/jjpa.22.3_129

    • NAID

      130006189399

    • ISSN
      1342-3215, 2432-0986
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] LEDの高速点滅光と非点滅光によるメラトニン分泌への影響2018

    • Author(s)
      小崎智照、日高勇樹、高倉潤也、草野洋介
    • Organizer
      日本人間工学会第59回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Melatonin suppression under light-emitting diode flickering and non-flickering light2018

    • Author(s)
      Tomoaki KOZAKI, Yuki HIDAKA, Jun-ya TAKAKURA, Yosuke KUSANO
    • Organizer
      20th International Ergonomics Association
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lighting Environment and Melatonin Secretion in modern society2018

    • Author(s)
      Tomoaki KOZAKI
    • Organizer
      International Symposium on Physiological Anthropology 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of 100 Hz flicker and non-flicker light on melatonin secretion2018

    • Author(s)
      Tomoaki KOZAKI, Yuki HIDAKA, Masato YANO, Jun-ya TAKAKURA, Yosuke KUSANO
    • Organizer
      The 8th Lux Pacifica
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] LEDの調光特性がメラトニン分泌抑制に及ぼす作用2017

    • Author(s)
      日高勇樹、矢野雅人、小崎智照
    • Organizer
      日本人間工学会第58回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 100Hzの高速点滅光と非点滅光によるメラトニン分泌への作用2017

    • Author(s)
      小崎智照、日高勇樹、高倉潤也、草野洋介
    • Organizer
      生理人類学会第75回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Melatonin Suppression under 100 Hz flicker light and non-flicker light.2017

    • Author(s)
      Tomoaki KOZAKI, Yuki HIDAKA, Masato YANO, Jun-ya TAKAKURA, Yosuke KUSANO
    • Organizer
      The 13th International Conference of Physiological Anthropology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lighting environment and melatonin secretion2016

    • Author(s)
      Kozaki T
    • Organizer
      UNIST-JPA Joint Symposium 2016 on Anthropological and Physiological Research on Humans Living in Modern Society of East Asia
    • Place of Presentation
      ウルサン市、大韓民国
    • Year and Date
      2016-09-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of flicker- and non-flicker-light on melatonin secretion at night2016

    • Author(s)
      Kozaki T, Katami K, Takakura J, Kusano Y
    • Organizer
      20th Congress of the European Anthropological Association
    • Place of Presentation
      ザグレブ市、クロアチア国
    • Year and Date
      2016-08-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高速フリッカー光と非フリッカー光によるメラトニン分泌抑制作用2016

    • Author(s)
      矢野雅人、日高勇樹、小崎智照
    • Organizer
      人類働態学会西日本地方会第41回大会
    • Place of Presentation
      飯塚市
    • Related Report
      2016 Annual Research Report
  • [Presentation] Light-induced melatonin suppression on different flicker frequency of the light2015

    • Author(s)
      Tomoaki Kozaki, Kenshin Katami, Toshihiko Arata, Jun'ya Takakura
    • Organizer
      The 12nd International Congress of Physiological Anthropology
    • Place of Presentation
      千葉市
    • Year and Date
      2015-10-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 定常光と高速点滅光がメラトニン分泌抑制に及ぼす影響2015

    • Author(s)
      傍示 顕信, 小崎 智照
    • Organizer
      平成27年度照明学会全国大会
    • Place of Presentation
      福井市
    • Year and Date
      2015-08-28
    • Related Report
      2015 Annual Research Report

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Published: 2015-04-16   Modified: 2020-03-30  

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