Development of next generation wood preservatives targeting supply chain of PQQ from bacteria to wood rotting fungi
| Project/Area Number |
15H04526
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Wood science
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
YOSHIDA Makoto 東京農工大学, (連合)農学研究科(研究院), 教授 (30447510)
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| Co-Investigator(Kenkyū-buntansha) |
五十嵐 圭日子 東京大学, 大学院農学生命科学研究科(農学部), 准教授 (80345181)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | 木材保存剤 / 微生物間相互作用 / PQQ / 木材腐朽 / 木材保存 |
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| Outline of Final Research Achievements |
Wood rotting fungi have been considered to cause the reduction in wood strength. Since this leads to a significant increase of the risk of collapse in wood structures, wood preservatives are used to prevent the phenomenon. Recently, the development of the wood preservatives with a low environmental burden are required in response to growing attention to environmental consideration.
We focused the fact that fungal pyranose dehydrogenase (PDH), which has been considered to work in the degradation of plant cell wall, uses pyrroloquinoline quinone (PQQ), which is provided from bacteria, as a cofactor. In the present study, inhibitor for PQQ-binding in PDH was selected, and its potential as a wood preservatives was evaluated.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] Structure of the catalytic domain of α-L-arabinofuranosidase from Coprinopsis cinerea, CcAbf62A, provides insights into structure-function relationships in glycoside hydrolase family 622017
Author(s)
Tonozuka, T., Tanaka, Y., Okuyama, S., Miyazaki, T., Nishikawa, A. and Yoshida, M.
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Journal Title
Applied Biochemistry and Biotechnology
Volume: 181
Issue: 2
Pages: 511-525
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Characterization of an LPMO from the brown-rot fungus Gloeophyllum trabeum with broad xyloglucan specificity, and its action on cellulose-xyloglucan complexes2016
Author(s)
Kojima, Y., Varnai, A., Ishida, T., Sunagawa, N., Petrovic, D., Igarashi, K., Jellison, J., Goodell, B., Alfredsen, G., Westereng, B., Eijsink, V., and Yoshida M.
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Journal Title
Appl. Environ. Microbiol.
Volume: 82
Issue: 22
Pages: 6557-6572
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] pH-dependent electron transfer reaction and direct bioelectrocatalysis of the quinohemoprotein pyranose dehydrogenase2016
Author(s)
Takeda, K., Matsumura, H., Ishida, T., Yoshida, M., Igarashi, K., Samejima, M., Hiroyuki Ohno, and Nakamura, N.
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Journal Title
Biochem. Biophys. Res. Commun.
Volume: 477
Issue: 3
Pages: 369-373
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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