Project/Area Number |
15H04587
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Animal production science
|
Research Institution | Kitasato University |
Principal Investigator |
|
Research Collaborator |
OHATA MOTOKO 日本大学, 生物資源科学部, 講師
KOMIYA YUSUKE 北里大学, 獣医学部, 助教
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2017: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2015: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
|
Keywords | 食肉 / ペプチド / ロイシン / 抗酸化作用 / メイラード反応 / 食品 / 保健的機能 |
Outline of Final Research Achievements |
Leucine-dipeptides were paid attention to study their functionalities and develop their industrial applications. Of 19 Leucine-dipeptides tested in this study, dipeptides containing Alanine, Arginine, or Lysine showed high antioxidative activities. In addition, Maillard reaction products generated from Leucine-dipeptides containing Arginine or Lysine increased their activities significantly. Orally administrated these materials with high activities decreased oxidative stress in animal bodies. Leucine-dipeptides, such as Leucine-Lysine and Lysine-Leucine would contribute to the prevention of atrophy of skeletal muscle associated with aging. From the results of this study along with previous observations, Leucine-dipeptides and their Maillard reaction products have important roles in meat and great possibility in the food industry.
|