| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2016: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Outline of Final Research Achievements |
The gut microbiota I of naked mole rat (worker、king、queen) and SPF mouse (Balb/c and C57BL/6) were compared. As the result of UniFrac analysis, naked mole rats had the peculiar gut microbiota. The gnotobiotic mice in this study were constructed by inoculating each gut microbiota (feces) of naked mole rat (worker and queen) to germ-free mouse (C57BL/6). The microbiota (feces) of guinea pig was used as a control. Sexual maturation tended to be delayed when transplanting the gut microbiota of queen naked mole rat rather than the control. Currently, we are conducting epigenetics analysis of the uterus and fallopian tube of queen naked mole rat with co-workers.
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