| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2018: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Outline of Final Research Achievements |
In cell division, the stable maintenance and accurate distribution of chromosomes are important for stable inheritance of genomes. The centromere and telomere regions on the eukaryotic chromosome play an extremely important role in stable maintenance and distribution of the chromosome. Here, we used a fission yeast as a model system and clarified one of the molecular mechanisms by which post-translational modification with the ubiquitin-like protein SUMO controls the functions of the centromeric and telomeric regions.
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