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Identification and clinical application of diagnostic and therapeutic marker of esophageal and gastric cancer targeting cancer stem cell

Research Project

Project/Area Number 15H04713
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionHiroshima University

Principal Investigator

YASUI WATARU  広島大学, 医歯薬保健学研究科(医), 教授 (40191118)

Co-Investigator(Renkei-kenkyūsha) OUE NAOHIDE  広島大学, 大学院医歯薬保健学研究科, 准教授 (60346484)
KUNIYASU HIROKI  奈良県立医科大学, 医学部, 教授 (00253055)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2017: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords食道癌 / 胃癌 / 癌幹細胞 / CAST法 / 新規診断・治療標的 / Spheroid / KIFC1 / KIF23 / DSG1 / IQGAP3 / MCOLN3 / BST2
Outline of Final Research Achievements

As candidate diagnostic and therapeutic targets of esophageal and gastric cancers associated with spheroid-forming cancer stem cells, kinesin family (KIFC1, KIF11, KIF23), IQGAP3, DSG1 were identified. BST2 and MCOLN3, identified from 5-FU-resistant gastric cancer cells, were found to regulate chemosensitivity. These findings will contribute to the application to the diagnosis and treatment for therapy-resistant cancer stem cells.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (64 results)

All 2017 2016 2015 Other

All Journal Article (18 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 18 results,  Open Access: 18 results,  Acknowledgement Compliant: 4 results) Presentation (44 results) (of which Int'l Joint Research: 8 results,  Invited: 13 results) Remarks (2 results)

  • [Journal Article] Overexpression of transmembrane protein BST2 induces phosphorylation of Akt and Erk in bladder cancer2017

    • Author(s)
      Shigematsu Y, Oue N, Nishioka Y, Sakamoto N, Sentani K, Sekino Y, Goto K, Teishima J, Matsubara A, Yasui W
    • Journal Title

      Oncology Letters

      Volume: 14 Pages: 999-1004

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Expression of BTS-2 Enhances Cell Growth and Invasiveness in Renal Cell Carcinoma2017

    • Author(s)
      Pham QT, Oue N, Yamamoto Y, Shigematsu Y, Sekino Y, Sakamoto N, Sentani K, Uraoka N, Tiwari M, Yasui W
    • Journal Title

      Anticancer Res

      Volume: 37 Pages: 2853-2860

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer.2017

    • Author(s)
      Oue N, Yamamoto Y, Oshima T, Asai R, Ishikawa A, Uraoka N, Sakamoto N, Sentani K, Yasui W.
    • Journal Title

      Pathobiology

      Volume: - Issue: 3 Pages: 192-200

    • DOI

      10.1159/000481890

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Overexpression of PCDHB9 promotes peritoneal metastasis and correlates with poor prognosis in patients with gastric cancer.2017

    • Author(s)
      Mukai S, Oue N, Oshima T, Imai T, Sekino Y, Honma R, Sakamoto N, Sentani K, Kuniyasu H, Egi H, Tanabe K, Yoshida K, Ohdan H, Yasui W.
    • Journal Title

      J Pathol

      Volume: 243 Issue: 1 Pages: 100-110

    • DOI

      10.1002/path.4931

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer2017

    • Author(s)
      Yuge R, Kitadai Y, Takigawa H, Naito T, Oue N, Yasui W, Tanaka S, Chayama K
    • Journal Title

      Transl Oncol

      Volume: 11 Issue: 3 Pages: 575-584

    • DOI

      10.1016/j.tranon.2018.02.003

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] SIX1 maintains tumor basal cells via TGF-β pathway and associates with poor prognosis in esophageal cancer2017

    • Author(s)
      Nishimura T, Tamaoki M, Komatsuzaki R, Oue N, Taniguchi H, Komatsu M, Aoyagi K, Minashi K, Chiwaki F, Shinohara H, Tachimori Y, Yasui W, Muto M, Yoshida T, Sakai Y, Sasaki H
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 2 Pages: 216-225

    • DOI

      10.1111/cas.13135

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] KIF11 is required for spheroid formation of oesophageal and colorectal cancers2017

    • Author(s)
      Imai T, Oue N, Sentani K, Sakamoto N, Uraoka N, Egi H, Hinoi T, Ohdan H, Yoshida K and Yasui W
    • Journal Title

      Anticancer Res

      Volume: 37 Pages: 47-55

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] KIFC1 induces resistance to docetaxel and is associated with survival of prostate cancer patients2017

    • Author(s)
      Sekino Y, Oue N, Shigematsu Y, Ishikawa A, Sakamoto N, Sentani K, Teishima J, Matsubara A, Yasui W
    • Journal Title

      Urologic Oncology

      Volume: 35 Issue: 1 Pages: 13-31

    • DOI

      10.1016/j.urolonc.2016.08.007

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Overexpression of KIF11 in gastric cancer with intestinal mucin phenotype2016

    • Author(s)
      Imai T, Oue N, Nishioka M, Mukai S, Oshima T, Sakamoto N, Sentani K, Matsusaki K, Yoshida K, Yasui W
    • Journal Title

      Pathobiology

      Volume: 84 Issue: 1 Pages: 16-24

    • DOI

      10.1159/000447303

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Induction of KIFC1 expression in gastric cancer spheroids2016

    • Author(s)
      Oue N, Mukai S, Imai T, Trang TBP, Oshima T, Sentani K, Sakamoto N, Yoshida K, Yasui W
    • Journal Title

      Oncology Reports

      Volume: 36 Issue: 1 Pages: 349-355

    • DOI

      10.3892/or.2016.4781

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Overexpression of transmembrane protein BST2, participating in cell growth, is associated with poor survival in patients with esophageal, gastric and colorectal cancer2016

    • Author(s)
      Mukai S, Oue N, Oshima T, Tatsumoto Y, Sakamoto N, Sentani N, Hinoi T, Ohdan H, Yasui W
    • Journal Title

      Annals of Surgical Oncology

      Volume: 24 Issue: 2 Pages: 594-602

    • DOI

      10.1245/s10434-016-5100-z

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Overexpression of transmembrane protein BST2, participating in cell growth, is associated with poor survival in patients with esophageal, gastric and colorectal cancer2016

    • Author(s)
      Mukai S, Oue N, Oshima T, Tatsumoto Y, Sakamoto N, Sentani N, Hinoi T, Ohdan H, Yasui W
    • Journal Title

      Ann Surg Oncol

      Volume: 印刷中

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fukutin, identified by the Escherichia coli ampicillin secretion trap (CAST) method, participates in tumor progression in gastric cancer.2016

    • Author(s)
      Oo HZ, Sentani K, Mukai S, Hattori T, Shinmei S, Goto K, Sakamoto N, Naito Y, Anami K, Trang PT, Yanagihara K, Oue N, Yasui W.
    • Journal Title

      Gastric Cancer

      Volume: 19 Issue: 2 Pages: 443-452

    • DOI

      10.1007/s10120-015-0511-2

    • NAID

      40020835493

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The transcribed-ultra conserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation.2015

    • Author(s)
      Keisuke Goto, Sho Ishikawa,Ririno Honma, Keiji Tanimoto, Naoya Sakamoto,Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara and Wataru Yasui.
    • Journal Title

      Oncogene

      Volume: 1 Issue: 27 Pages: 1-1

    • DOI

      10.1038/onc.2015.445

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] TSPAN8, identified by Escherichia coli ampicillin secretion trap, is associated with cell growth and invasion in gastric cancer2015

    • Author(s)
      Katsuhiro Anami, Naohide Oue, Tsuyoshi Noguchi, Naoya Sakamoto, Kazuhiro Sentani, Tetsutaro Hayashi, Yutaka Naito, Htoo Zarni Oo, Wataru Yasui
    • Journal Title

      Gastric Cancer

      Volume: ahead of print Issue: 2 Pages: 370-380

    • DOI

      10.1007/s10120-015-0478-z

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype2015

    • Author(s)
      Oue N, Sentani K, Sakamoto N, Yasui W
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 8 Pages: 951-958

    • DOI

      10.1111/cas.12706

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] New molecular staging with G-factor supplements TNM classification in gastric cancer: A multicenter collaborative research by the Japanese Society for Gastroenterological Carcinogenesis G-Project committee2015

    • Author(s)
      Sawada T, Yashiro M, Sentani K, Oue N, Yasui W, Miyazaki K, Kai K, Fushida S, Fujimura T, Ohira M, Kakeji Y, Natsugoe S, Shirabe K, Nomura S, Shimada Y, Tomita N, Hirakawa K, Maehara Y
    • Journal Title

      Gastric Cancer

      Volume: 18 Issue: 1 Pages: 119-128

    • DOI

      10.1007/s10120-014-0338-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer.2015

    • Author(s)
      Fujii S, Fujihara A, Natori K, Abe A, Kuboki Y, Higuchi Y, Aizawa M, Kuwata T, Kinoshita T, Yasui W, Ochiai A.
    • Journal Title

      Cancer Med.

      Volume: 4 Issue: 11 Pages: 1667-1678

    • DOI

      10.1002/cam4.515

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Molecular pathology of gastric cancer in the past, present and future precision medicine2017

    • Author(s)
      Yasui W
    • Organizer
      第89回日本胃癌学会総会
    • Place of Presentation
      広島
    • Year and Date
      2017-03-08
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] The value and challenge of HER2 pathways in gastric cancer therapy2017

    • Author(s)
      Yasui W, Oue N, Sentani K, Sakamoto N
    • Organizer
      12th International Gastric Cancer Congress
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular pathology of cancer in the past, present and future precision medicine2017

    • Author(s)
      安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 胃癌の病理 -現状と展望-2017

    • Author(s)
      安井 弥
    • Organizer
      第55回日本癌治療学会学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 食道癌および大腸癌におけるKinesin family member 11の発現・機能解析2017

    • Author(s)
      今井健晴、山本悠司、大上直秀、坂本直也、仙谷和弘、吉田和弘、安井 弥.
    • Organizer
      第106回日本病理学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] IQGAP3の発現誘導と胃癌におけるスフェロイド形成2017

    • Author(s)
      大上直秀、山本悠司、今井健晴、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第106回日本病理学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 膜蛋白質IQGAP3は胃癌の進行に関与する2017

    • Author(s)
      大上直秀、今井健晴、山本悠司、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第26回日本がん転移学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 腎癌におけるBST2の発現・機能解析2017

    • Author(s)
      Pham Quoc Thang、関野陽平、大上直秀、重松慶紀、坂本直也、仙谷和弘、亭島 淳、松原昭郎、安井 弥
    • Organizer
      第26回日本がん転移学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 胃癌におけるKIF23の発現解析とスフェロイド形成への影響2017

    • Author(s)
      浅井竜一、今井健晴、山本悠司、大上直秀、仙谷和弘、坂本直也、吉田和弘、安井 弥
    • Organizer
      第14回日本病理学会カンファレンス
    • Related Report
      2017 Annual Research Report
  • [Presentation] 膀胱癌におけるKIF23の発現・機能解析2017

    • Author(s)
      重松慶紀、大上直秀、関野陽平、坂本直也、仙谷和弘、亭島 淳、松原昭郎、安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] BST-2の発現は増殖能・浸潤能に関係する2017

    • Author(s)
      Pham Quoc Thang、大上直秀、山本悠司、重松慶紀、関野陽平、坂本直也、仙谷和弘、浦岡直礼、Tiwari Mamata、安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] KIF23は食道癌・大腸癌細胞におけるスフェロイド形成に必要である2017

    • Author(s)
      浅井竜一、大上直秀、今井健晴、山本悠司、福永武史、坂本直也、仙谷和弘、吉田和弘、安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] IQGAP3の発現は胃癌の予後不良と関連する2017

    • Author(s)
      大上直秀、山本悠司、今井健晴、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] KIF23の発現は胃癌の予後と相関する2017

    • Author(s)
      山本悠司、大上直秀、今井健晴、浅井竜一、坂本直也、仙谷和弘、大段秀樹、安井 弥
    • Organizer
      第76回日本癌学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] IQGAPは胃癌の予後と相関する2017

    • Author(s)
      大上直秀、山本悠司、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第28回日本消化器癌発生学会総会・第9回国際消化器癌発生会議
    • Related Report
      2017 Annual Research Report
  • [Presentation] Cross-disciplinary approach to control gastric cancer in precision medicine2016

    • Author(s)
      Yasui W
    • Organizer
      The 2016 Annual Congress of Korean Surgical Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-11-03
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 食道扁平上皮癌におけるKIFC1の発現と幹細胞の関連2016

    • Author(s)
      服部 結、大上直秀、服部拓也、今井健晴、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 膀胱癌におけるBST2の発現・機能解析2016

    • Author(s)
      重松慶紀、大上直秀、関野陽平、向井正一朗、後藤景介、仙谷和弘、亭島 淳、松原昭郎、安井 弥
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 食道扁平上皮癌におけるKinesis family member11の発現解析2016

    • Author(s)
      石川 洸、今井健晴、向井正一朗、坂本直也、仙谷和弘、大上直秀、安井 弥
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] KIF11は腸型胃癌の発生に関与する2016

    • Author(s)
      今井健晴、大上直秀、向井正一朗、坂本直也、仙谷和弘、吉田和弘、安井 弥
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 膜貫通蛋白質PCDHB9は接着及び播種を促進し胃癌の予後不良に関与する2016

    • Author(s)
      大上直秀、向井正一朗、今井健晴、國安弘基、仙谷 和弘、坂本直也、大段秀樹、吉田和弘 、安井 弥
    • Organizer
      第27回日本消化器癌発生学会総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-09-15
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Molecular pathological approach to develop novel cancer diagnostics and therapeutics2016

    • Author(s)
      Yasui W
    • Organizer
      The 27th Annual Meeting of the Japanese Society of Oral Pathology
    • Place of Presentation
      Hiroshima (Japan)
    • Year and Date
      2016-08-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Kinesin family member11の胃癌における発現・機能解析2016

    • Author(s)
      今井健晴、大上直秀、仙谷和弘、安井 弥
    • Organizer
      第25回日本がん転移学会学術集会
    • Place of Presentation
      米子
    • Year and Date
      2016-07-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] Assessment and clinical application of markers for stratification of recurrence risk after curative resection of stage II/III gastric cancer2016

    • Author(s)
      Oshima T, Kimura Y, Sakamaki K, Miyagi Y, Yamanaka S, Oue N, Cho H, Yoshikawa T, Rino Y, Yasui W, Imada T, Masuda M
    • Organizer
      The 2016 ASCO Annual Meeting
    • Place of Presentation
      Illinois, Chicago (USA)
    • Year and Date
      2016-06-03
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 胃癌におけるKinesin family member11の発現・機能解析2016

    • Author(s)
      今井健晴、向井正一朗、大上直秀、仙谷和弘、吉田和弘、安井 弥
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] 胃癌におけるPCDHB9の機能および発現意義について2016

    • Author(s)
      向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、安井 弥
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] 胃癌に対する病理診断2016

    • Author(s)
      安井 弥
    • Organizer
      Gastric Cancer Symposium in 中四国
    • Place of Presentation
      岡山
    • Year and Date
      2016-03-12
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 病理からみた胃癌とは?2016

    • Author(s)
      安井 弥
    • Organizer
      Taiho Gastric Cancer Forum in West Japan-
    • Place of Presentation
      神戸
    • Year and Date
      2016-01-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] KIF C1とKIF 11の胃癌における分子腫瘍マーカーとしての意義2016

    • Author(s)
      今井健晴、大上直秀、坂本直也、仙谷和弘、吉田和弘、安井 弥
    • Organizer
      第36回日本分子腫瘍マーカー研究会
    • Place of Presentation
      横浜
    • Related Report
      2016 Annual Research Report
  • [Presentation] 胃癌幹細胞およびスフェロイド形成におけるKIFC1の役割2015

    • Author(s)
      大上直秀、向井正一朗、今井健晴、T.B.Pham Trang、仙谷和弘、安井 弥
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子
    • Year and Date
      2015-11-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] Molecular pathology of gastric cancer2015

    • Author(s)
      Yasui W
    • Organizer
      The 2nd International Forum for Japan and Korea Medical Exchange
    • Place of Presentation
      Kure, Japan
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 胃癌におけるPCDHB9の発現とその意義2015

    • Author(s)
      向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、安井 弥
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] KIFC1は胃癌細胞のスフェロイド形成に重要である2015

    • Author(s)
      大上直秀、向井正一朗、Pham T.B Trang、仙谷和弘、安井 弥
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 食道扁平上皮癌におけるPCDHB9の機能解析2015

    • Author(s)
      今井健晴、向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、吉田和弘、安井 弥
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 食道癌におけるBST2の発現2015

    • Author(s)
      服部 結、大上直秀、Htoo Zarni Oo、向井正一朗、仙谷和弘、大段秀樹、安井 弥
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] SAGE法・CAST法から同定した胃癌関連マーカーとその意義2015

    • Author(s)
      大上直秀、仙谷和弘、坂本直也、浦岡直礼、服部拓也、安井 弥
    • Organizer
      第35回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-07
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Molecular pathology of gastric cancer2015

    • Author(s)
      Yasui W
    • Organizer
      JP Kim Memorial International Gastric Cancer Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-07-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 胃癌細胞のスフェロイド形成におけるKIFC1の役割2015

    • Author(s)
      大上直秀、向井正一朗、Pham T.B. Trang、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] Endoscopic management of early gastric cancer: Molecular analysis in endoscopic specimen2015

    • Author(s)
      Yasui W
    • Organizer
      The 11th International Gastric Cancer Congress
    • Place of Presentation
      Sao Paulo, Brazil
    • Year and Date
      2015-06-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 胃癌におけるBST2発現は5-FU感受性と関連がある.2015

    • Author(s)
      向井正一朗、大上直秀、仙谷和弘、Htoo Zarni Oo、大段秀樹、安井 弥
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] CAST法を用いて同定したBST2の食道癌における機能解析2015

    • Author(s)
      立本淑子、向井正一朗、PhamThi Binh Trang、大上直秀、仙谷和弘、安井 弥
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 胃癌におけるスフェロイド形成関連遺伝子と癌幹細胞との関連2015

    • Author(s)
      大上直秀、向井正一朗、Pham T.B Trang、坂本直也、仙谷和弘、安井 弥
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 食道扁平上皮癌におけるolfactomedin4発現に関する分子病理学的検討2015

    • Author(s)
      浦岡直礼、大上直秀、仙谷和弘、向井正一朗、服部拓也、野口 剛、安井 弥
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Significance of KIFC1 in spheroid formation of gastric cancer cells.2015

    • Author(s)
      Oue N, Mukai S, Pham TBT, Sentani K, Yasui W
    • Organizer
      AACR (American Association for Cancer Research) Annual Meeting 2015
    • Place of Presentation
      Philadelphia, Pennsylvania (USA)
    • Year and Date
      2015-04-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Remarks] 広島大学大学院分子病理学研究室

    • URL

      http://home.hiroshima-u.ac.jp/byori1/

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
  • [Remarks] 広島大学大学院分子病理学研究室ホームページ

    • URL

      http://home.hiroshima-u.ac.jp/byori1/

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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