Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
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Outline of Final Research Achievements |
Bacterial cell shape is regulated by cytoskeletal proteins which are homologs of eukaryotic cytoskeletal proteins. In this study, we analyzed functions and subcellular localizations of MreB actin and its regulator protein RodZ. We found that compositions of phospholipids are important for subcellular localizations and motions of MreB. We also showed that RodZ self-interacts in the periplasmic domain. In addition, the transmembrane region of RodZ is vital for its function. We published two papers and a review in international scientific journals. We are now preparing one more paper to publish.
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