An analysis for the outbreak of multiple drug resistance Acinetobactor Baumannii in the critical care center
| Project/Area Number |
15H04795
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical and hospital managemen
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| Research Institution | University of Tsukuba (2016-2017)
Juntendo University (2015) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
佐々木 信一 順天堂大学, 医学部, 先任准教授 (40281357)
岡本 健 順天堂大学, 医学部, 教授 (40347076)
田中 裕 順天堂大学, 医学(系)研究科(研究院), 教授 (90252676)
角 由佳 順天堂大学, 医学部, 非常勤講師 (40403084)
末吉 孝一郎 順天堂大学, 医学部, 助教 (90648297)
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| Research Collaborator |
NAKAZAWA Takeshi
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
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| Keywords | Acinetobacter Baumannii / 院内感染 / 遺伝子解析 / 効率的隔離策 / Acinetobactor Baumannii / アウトブレイク / 抗菌薬耐性 / 適正隔離 / PCR解析 / PCR / 感染症 / 細菌 / アシネトバクターバウマニ |
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| Outline of Final Research Achievements |
Multi Drug Resistant Acinetobactor Baumannii (MDRA) was one of the major problems for nasocomical infection that was outbreaked including the dead in the some critical care center recently. We analyzed 63 patients with positive Acinetobactor Baumannii specimen and compared the resistance of antibiotics. Gene patterns of MDRA were clearly correlated to the resistance of antibiotics, so we ensured the isolation protocol with gene pattern for the patients with Acinetobactor Baumannii colonization. We succeeded the end of outbreak for MDRA based on PCR oriented isolation for Acinetobactor Baumannii.
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] Landiolol hydrochloride ameliorates acute lung injury in a rat model of early sepsis through the suppression of elevated levels of pulmonary endothelin-12016
Author(s)
Yujiro Matsuishi, Subrina Jesmin, Satoru Kawano, Sakuramoto Hideaki, Nobutake Shimojo, Chishimba Nathan Mowa, Shila Akhtar, Sohel Zaedi, Tanzila Khatun, Yoshiya Tsunoda, Takumi Kiwamoto, Nobuyuki Hizawa, Yoshiaki Inoue, Taro Mizutani
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Journal Title
Life Science
Volume: 166
Pages: 27-33
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] カテーテル関連性感染症2017
Author(s)
井上 貴昭
Organizer
第44回日本集中治療医学会総会・学術集会
Place of Presentation
ロイトン札幌、北海道札幌市
Year and Date
2017-03-09
Related Report
Invited
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[Presentation] 遺伝子解析によるアシネトバクター属菌の菌種と耐性菌評価2016
Author(s)
村田 健介, 井上 貴昭, 角 由佳, 岡本 健, 秋田 美佳, 中村 美子, 海宝 まゆ子, 中沢 武司, 佐々木 信一, 田中 裕
Organizer
第44回日本救急医学会総会・学術集会
Place of Presentation
グランドプリンスホテル新高輪、東京都港区
Year and Date
2016-11-17
Related Report
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