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The clarification of pathophysiology in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder

Research Project

Project/Area Number 15H04889
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionHirosaki University

Principal Investigator

Nakamura Kazuhiko  弘前大学, 医学研究科, 教授 (80263911)

Co-Investigator(Kenkyū-buntansha) 上野 伸哉  弘前大学, 医学研究科, 教授 (00312158)
斉藤 まなぶ  弘前大学, 医学部附属病院, 講師 (40568846)
古川 智範  弘前大学, 医学研究科, 助教 (60402369)
下山 修司  弘前大学, 医学研究科, 助教 (60736370)
尾崎 拓  岩手大学, 理工学部, 准教授 (70621069)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
KeywordsAutism Spectrum Disorder / ADHD / 児童・思春期精神医学 / 自閉症スペクトラム / 注意欠如・多動性障害 / CNV / 精神医学
Outline of Final Research Achievements

Since ASD have been thought to be arisen from genetic factors, we examined genetic analysis in Japanese patients with autism spectrum disorder (ASD). This study revealed that the patients with ASD have the characteristic copy number variation region and these regions were overlapped with previous studies in Westerners patients with ASD. However, the odds ratio was higher than previous study. This result indicated that detected region was crucial for Japanese patients with ASD.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (86 results)

All 2018 2017 2016 2015

All Journal Article (25 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 25 results,  Open Access: 17 results,  Acknowledgement Compliant: 2 results) Presentation (60 results) (of which Int'l Joint Research: 20 results,  Invited: 1 results) Book (1 results)

  • [Journal Article] Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder2018

    • Author(s)
      Takata A, Miyake N, Tsurusaki Y, Fukai R, Miyatake S, Koshimizu E, Kushima I, Okada T, ...Matsumoto N.
    • Journal Title

      Cell Reports

      Volume: 22(3) Issue: 3 Pages: 734-747

    • DOI

      10.1016/j.celrep.2017.12.074

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Differences in sleep problems between Japanese and Chinese preschoolers: a cross-cultural comparison within the Asian region2018

    • Author(s)
      Takahashi Michio、Wang Guanghai、Adachi Masaki、Jiang Fan、Jiang Yanrui、Saito Manabu、Nakamura Kazuhiko
    • Journal Title

      Sleep medicine

      Volume: 印刷中 Pages: 42-48

    • DOI

      10.1016/j.sleep.2017.11.1145

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] MHC class I in dopaminergic neurons suppresses relapse to reward seeking.2018

    • Author(s)
      Murakami G, Edamura M, Furukawa T, Kawasaki H, Kosugi I, Fukuda A, Iwashita T, Nakahara D.
    • Journal Title

      Sci Adv.

      Volume: 4(3)

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Alteration of autophagy-related proteins in peripheral blood mononuclear cells of patients with Parkinson's disease2018

    • Author(s)
      Miki Yasuo、Shimoyama Shuji、Kon Tomoya、Ueno Tatsuya、Hayakari Ryo、Tanji Kunikazu、Matsumiya Tomoh、Tsushima Eiki、Mori Fumiaki、Wakabayashi Koichi、Tomiyama Masahiko
    • Journal Title

      Neurobiology of aging

      Volume: 63 Pages: 33-43

    • DOI

      10.1016/j.neurobiolaging.2017.11.006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Poor motor-function recovery after spinal-cord injury in anxiety-model mice with phospholipase related catalytically inactive protein type 1 knockout.2018

    • Author(s)
      Taka Fujita, Gentaro Kumagai, Xizhe Liu, Kanichiro Wada, Toshihiro Tanaka, Hitoshi Kudo, Toru Asari, Tatsuhiro Fukutoku, Ayako Sasaki, Yohshiro Nitobe, Yoshikazu Nikaido, Ken-Ichi Furukawa, Masato Hirata, Takashi Kanematsu, Shinya Ueno, Yasuyuki Ishibash
    • Journal Title

      Journal of Neurotrauma

      Volume: 印刷中 Issue: 12 Pages: 1379-1386

    • DOI

      10.1089/neu.2017.5492

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The prevalence of sleep problems among Japanese preschoolers in a medium-sized city: A community-based survey using the Children’s Sleep Habits Questionnaire2017

    • Author(s)
      Takahashi M, Adachi M, Yasuda S, Osato-Kaneda A, Saito M, Kuribayashi M, Nakamura K., Article accepted on 14 March, 2017,
    • Journal Title

      Pediatrics International (in press)

      Volume: 印刷中 Issue: 6 Pages: 747-750

    • DOI

      10.1111/ped.13281

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice2017

    • Author(s)
      Morimura Naoko、Yasuda Hiroki、Yamaguchi Kazuhiko、Katayama Kei-ichi、Hatayama Minoru、Tomioka Naoko H.、Odagawa Maya、Kamiya Akiko、Iwayama Yoshimi、Maekawa Motoko、Nakamura Kazuhiko、Matsuzaki Hideo、Tsujii Masatsugu、Yamada Kazuyuki、Yoshikawa Takeo、Aruga Jun
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 15800-15800

    • DOI

      10.1038/ncomms15800

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Coordination difficulties in preschool-aged children are associated with maternal parenting stress: A community-based cross-sectional study.2017

    • Author(s)
      Takahashi M, Adachi M, Takayanagi N, Yasuda S, Tanaka M, Osato-Kaneda A, Masuda T, Nakai A, Saito M, Kuribayashi M, Nakamura K
    • Journal Title

      Research inDevelopmental Disabilities.

      Volume: 70 Pages: 11-23

    • DOI

      10.1016/j.ridd.2017.08.002

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spine enlargement of pyramidal tract-type neurons in the motor cortex of a rat model of levodopa-induced dyskinesia2017

    • Author(s)
      Tatsuya Ueno, Haruo Nishijima, Shinya Ueno and Masahiko Tomiyama
    • Journal Title

      Frontiers in Neuroscience

      Volume: 11 Pages: 206-206

    • DOI

      10.3389/fnins.2017.00206

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Propofol anesthesia is reduced in Phospholipase C-related inactive protein type-1 knockout mice2017

    • Author(s)
      Nikaido Y, Furukawa T, Shimoyama S, Yamada J, Migita K, Koga K, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S
    • Journal Title

      The Journal of pharmacology and experimental therapeutics

      Volume: 361(3) Issue: 3 Pages: 367-374

    • DOI

      10.1124/jpet.116.239145

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Morphological dendritic spine changes of medium spiny neurons in the nucleus accumbens in 6-hydroxydopamine-lesioned rats treated with levodopa.2017

    • Author(s)
      Funamizu Y, Nishijima H, Ueno T, Ueno S, Mizukami H, Yagihashi S, Tomiyama M.
    • Journal Title

      Neurosci Res.

      Volume: 121 Pages: 49-53

    • DOI

      10.1016/j.neures.2017.03.010

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Levodopa treatment and dendritic spine pathology.2017

    • Author(s)
      Nishijima H, Ueno T, Funamizu Y, Ueno S, Tomiyama M.
    • Journal Title

      Mov Disord.

      Volume: 印刷中 Issue: 6 Pages: 877-888

    • DOI

      10.1002/mds.27172

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chronic diazepam administration increases the expression of Lcn2 in the CNS2017

    • Author(s)
      Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi & Shinya Ueno
    • Journal Title

      Pharmacology Research & Perspectives

      Volume: 5(1) Issue: 1 Pages: 1-12

    • DOI

      10.1002/prp2.283

    • NAID

      120006576912

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psychometric properties of the Japanese ADHD-RS in preschool children.2016

    • Author(s)
      Takayanagi N, Yoshida S, Yasuda S, Adachi M, Kaneda-Osato A, Tanaka M, Masuda T, Kuribayashi M, Saito M, Nakamura K.
    • Journal Title

      Res Dev Disabil.

      Volume: 55 Pages: 268-78

    • DOI

      10.1016/j.ridd.2016.05.002

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comprehensive Review Of Current Findings of Callous and Unemotional Traits2016

    • Author(s)
      Yoshida S, Takayanagi N, Adachi M, Yasuda S, Nakamura, K.
    • Journal Title

      Hirosaki Med

      Volume: 67 Pages: 1-12

    • NAID

      130008041711

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enrichment of deleterious variants of mitochondrial DNA polymerase gene (POLG1) in bipolar disorder2016

    • Author(s)
      Kasahara T, Ishiwata M, Kakiuchi C, Fuke S, Iwata N, Ozaki N, Kunugi H, Minabe Y, Nakamura K, Iwata Y, Fujii K, Kanba S, Ujike H, Kusumi I, Kataoka M, Matoba N, Takata A, Iwamoto K, Yoshikawa T, Kato T
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 71 Issue: 8 Pages: 518

    • DOI

      10.1111/pcn.12496

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 5歳児発達健診における発達障害の疫学2016

    • Author(s)
      斉藤まなぶ, 吉田 恵心 , 坂本 由唯 , 大里 絢子 , 足立 匡基 , 安田 小響 , 栗林 理人 , 中村 和彦
    • Journal Title

      日本生物学的精神医学会誌

      Volume: 27(2) Pages: 60-64

    • NAID

      130006338396

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 特集 乳幼児精神医学  5歳児健診の現状と課題2016

    • Author(s)
      斉藤まなぶ, 吉田恵心, 高柳伸哉, 安田小響, 足立匡基, 大里絢子, 中村和彦
    • Journal Title

      児童青年精神医学とその近接領域

      Volume: 57(2) Pages: 254-260

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ASSQ短縮版の5歳児適用における妥当性2016

    • Author(s)
      足立匡基, 高柳伸哉, 吉田恵心, 安田小響, 大里絢子, 田中勝則, 増田貴人, 栗林理人, 斉藤まなぶ, 中村和彦
    • Journal Title

      児童青年精神医学とその近接領域

      Volume: 57(4) Pages: 603-617

    • NAID

      130006865848

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自閉症スペクトラム障害の早期発見―5歳児健診 (特集 発達支援のアセスメント) -- (発達障害の早期発見のアセスメント)2016

    • Author(s)
      斉藤まなぶ・吉田恵心・髙柳伸哉・安田小響・足立匡基・大里絢子・中村和彦
    • Journal Title

      臨床心理学

      Volume: 16(2) Pages: 145-150

    • NAID

      40020748218

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.2015

    • Author(s)
      Chie Shimamoto, Tetsuo Ohnishi, Motoko Maekawa, Akiko Watanabe, Hisako Ohba, Ryoichi Arai, Yoshimi Iwayama, Yasuko Hisano, Tomoko Toyota, Manabu Toyoshima, Katsuaki Suzuki, Yukihiko Shirayama, Kazuhiko Nakamura, Norio Mori, Yuji Owada, Tetsuyuki Kobayashi, Takeo Yoshikawa
    • Journal Title

      Human Molecular Genetics

      Volume: 24(8) Issue: 8 Pages: 2409-2409

    • DOI

      10.1093/hmg/ddv011

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psychometric properties of the Repetitive Behavior Scale-Revised for individuals with autism spectrum disorder in Japan2015

    • Author(s)
      Inada N, Ito H, Yasunaga K, Kuroda M, Iwanaga R, Hagiwara T, Tani I, Yukihiro R, Uchiyama T, Ogasahara K, Hara K, Inoue M, Murakami T, Someki F, Nakamura K, Sugiyama T, Uchida H, Ichikawa H, Kawakubo Y, Kano Y, Tsujii M
    • Journal Title

      Research in Autism Spectrum Disorder

      Volume: In press Pages: 60-68

    • DOI

      10.1016/j.rasd.2015.01.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CNV Analysis and Exome Sequencing in Japanese Autism Spectrum Disorder Subjects2015

    • Author(s)
      Nakamura K, Thanseem I, Mori N, Tsujii M, Matsumoto N
    • Journal Title

      NEUROPSYCHOPHARMACOLOGY

      Volume: 40

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epidemiology of autism spectrum disorder and attention deficit hyperactivity disorder in a community-based population sample of five-year-olds children2015

    • Author(s)
      Saito M , Kaneda-osato A, Tanaka M, Masuda T, Takayanagi N , Yasuda S , Nakamura K
    • Journal Title

      EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

      Volume: 24

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 某市5歳児発達健診における発達障害の疫学2015

    • Author(s)
      斉藤 まなぶ,大里 絢子, 田中 勝則, 増田 貴人, 高柳 伸哉, 安田 小響, 中村 和彦
    • Journal Title

      精神神経学雑誌

      Volume: 117(5) Pages: 372-372

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] The effect of chronic diazepam administration on hippocampal long-term potentiation and spine morphology.2018

    • Author(s)
      T. Furukawa, Y. Nikaido, S. Shimoyama, Y. Ogata, K. Nakamura, S. Ueno.
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Chronic diazepam administration increases the expression of Lcn2 in the CNS2017

    • Author(s)
      Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi, and Shinya Ueno
    • Organizer
      第94回 日本生理学会
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] Chronic diazepam administration impairs acquisition of spatial reference memory in aged mice2017

    • Author(s)
      Yoshikazu Nikaido, Tomonori Furukawa, Shuji Shimoyama, Kohei Koga, and Shinya Ueno
    • Organizer
      第94回 日本生理学会
    • Place of Presentation
      アクトシティ浜松(静岡県・浜松市)
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] Gaze Abnormality Can Distinguish Between Autism Spectrum Disorder and Typically Developing Children through Screening in 5-Year-Old Children By a Double Study in a Japanese Community Based Population2017

    • Author(s)
      M.Saito,M.Adachi,S.Yoshida,S.Yasuda,M.Kuribayashi,Y.Sakamoto,K.Nakamura and N.Takayanagi,
    • Organizer
      INTERNATIONAL MEETING FOR AUTISM RESEARCH(IMFAR2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prevalence and Comorbidities of Autism Spectrum Disorder and Study of the Method of the Developmental Health Checkup in a Japanese Community-Based Population Sample of Five-Year-Old Children2017

    • Author(s)
      Y.Sakamoto,M.S,aito,S.Yoshida,M.Adachi,N.Takayanagi,S.Yasuda,M.Kuribayashi,and K.Nakamura
    • Organizer
      INTERNATIONAL MEETING FOR AUTISM RESEARCH(IMFAR2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 自閉症の超早期療育-Early Start Denver Model-の紹介2017

    • Author(s)
      大里絢子、斉藤まなぶ、服巻智子、坂本由唯、松原侑里、中村和彦
    • Organizer
      第19回東北児童青年精医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小中学生におけるインターネット依存傾向と内在化・外在化問題・発達的特性との関連2017

    • Author(s)
      足立匡基・髙橋芳雄・安田小響・栗林理人・中村和彦
    • Organizer
      第19回東北児童青年精神医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 市内小中学生におけるインターネット依存傾向の実態とメンタルヘルスとの関連について2017

    • Author(s)
      髙橋芳雄、足立匡基、安田小響、栗林理人、中村和彦
    • Organizer
      第101回弘前医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 注視点測定を用いた5歳児のASD傾向の検討2017

    • Author(s)
      斉藤まなぶ、大里絢子、土屋賢治、坂本由唯、松原侑里、吉田恵心、足立匡基、高橋芳雄、安田小響、松田侑子、増田貴人、栗林理人、中村和彦
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 注意欠如・多動性障害(ADHD)のEye Tracking Pattern2017

    • Author(s)
      松原侑里、斉藤まなぶ、坂本由唯、吉田恵心、大里絢子、足立匡基、高橋芳雄、安田小響、栗林理人、土屋賢治、中村和彦
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 視線検出装置(Gazefinder)による女児自閉症スペクトラム障害(ASD)の早期診断の有用性2017

    • Author(s)
      坂本由唯、斉藤まなぶ、松原侑里、吉田恵心、大里絢子、足立匡基、高橋芳雄、安田小響、栗林理人、土屋賢治、中村和彦
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 児童期のADHDと成人期のADHDの連続性について 「成人期のADHDの脳画像研究について」(シンポジウム)2017

    • Author(s)
      中村和彦
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Prevalence and Comorbidities of DCD Using DSM-5,Comparison of Motor and Cognitive functions at Preschool Age in a Japanese Community2017

    • Author(s)
      Kazutaka Yoshida,Michio Takahashi,Ayako Osato-Kaneda, Masanori Tanaka,Takahito Masuda,Satomi Yoshida, Yui Sakamoto,Yuri Matsubara, Nobuya Takayanagi, Masaki Adachi, Manabu Saito,Sayura Yasuda,Michito Kuribayashi,Akio Nakai, Motohide Miyahara,Kazuhiko Nakamura,
    • Organizer
      International Conference for Developmental Coordination Disorder(DCD12)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Behavioral problems in preschool children with Developmental Coordination Disorder.2017

    • Author(s)
      Adachi M, Takayanagi N, Takahashi M, Yasuda S, Yoshida S, Mikami M, Nakai A, Saito M, Nakamura K.
    • Organizer
      International Conference for Developmental Coordination Disorder (DCD12)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The parental and tescher’s recognition for Developmental Coordination Disorder in preschool-aged children.2017

    • Author(s)
      Mikami M, Saito M, Masuda T, Tanaka M, Osato A, Sakamoto Y, Yoshida S, Takayanagi N, Adachi M, Yasuda S, Kuribayashi M, Nakamura K.
    • Organizer
      International Conference for Developmental Coordination Disorder (DCD12)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Developmental Coordination Disorder trait in Japanese preschoolers impact on parenting stress.2017

    • Author(s)
      Takahashi M, Adachi M, Takayanagi N, Yasuda S, Osato-Kaneda A, Mikami M, Nakai A, Saito M, Kuribayashi M, Nakamura K.
    • Organizer
      International Conference for Developmental Coordination Disorder. (DCD12)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation of factor structure equivalence of the Developmental Coordination Disorder Questionnaire across genders in Japanese preschool children.2017

    • Author(s)
      Tanaka M, Saito M, Kaneda-Osato A, Masuda T, Takayanagi N, Takahashi M, Adachi M, Yasuda S, Yoshida S, Kuribayashi, M, Nakai A, Miyahara M, Nakamura K, Sakamoto Y.
    • Organizer
      International Conference for Developmental Coordination Disorder. (DCD12)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Epidemiology of Developmental Coordination Disorder, Prevalence and Comorbidities Using DSM-5, and Diagnostic predictability by Developmental Coordination Disorder Questionnaire (DCDQ)at Preschool Age in a Japanese Community.2017

    • Author(s)
      Manabu Saito,Ayako Osato-Kaneda, Masanori Tanaka, Takahito Masuda, Satomi Yoshida, Yui Sakamoto, Kazutaka Yoshida, Yuri Matsubara, Nobuya Takayanagi, Masaki Adachi, Michio Takahashi, Sayura Yasuda, Michito Kuribayashi, Akio Nakai, Kazuhiko Nakamura
    • Organizer
      (The 9th Congress of The Asian Society for Child and Adlescent Psychiatry and Allied Professions (ASCAPAP)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 発達性強調運動障害(DCD)の疫学及び認知特性2017

    • Author(s)
      吉田和貴、斉藤まなぶ、坂本由唯、大里絢子、三上美咲、足立匡基、安田小響、増田貴人、田中勝則、吉田恵心、栗林理人、中村和彦
    • Organizer
      第58回日本児童青年精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 注意欠如・多動性障害(ADHD)のGaze Tracking Pattern2017

    • Author(s)
      斉藤まなぶ、坂本由唯、大里絢子、吉田恵心、足立匡基、安田小響、増田貴人、田中勝則、栗林理人、中村和彦
    • Organizer
      第58回日本児童青年精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Gaze Tracking Patternを用いた5歳児の閾値以下のASD特性と性差の検討2017

    • Author(s)
      斉藤まなぶ、坂本由唯、大里絢子、吉田恵心、足立匡基、安田小響、増田貴人、田中勝則、栗林理人、中村和彦
    • Organizer
      第58回日本児童青年精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Gaze Tracking Patternと既存の評価尺度を用いた5歳児自閉症スペクトラム障害(ASD)のスクリーニング及び診断ツールの有用性2017

    • Author(s)
      坂本由唯、斉藤まなぶ、大里絢子、吉田恵心、足立匡基、安田小響、増田貴人、田中勝則、栗林理人、中村和彦
    • Organizer
      第58回日本児童青年精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 日本語版Developmental Coordination Disorder Questionnaire(DCDQ)における予測的妥当性2017

    • Author(s)
      田中勝則、斉藤まなぶ、中井昭夫、大里絢子、増田貴人、高柳伸哉、高橋芳雄、足立匡基、安田小響、吉田恵心、坂本由唯、栗林理人、中村和彦
    • Organizer
      第58回日本児童青年精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The effect of chronic diazepam administration induced upregulation of Lcn2 expression on cognitive function2017

    • Author(s)
      Y. Ogata, T. Furukawa, Y. Nikaido, S. Shimoyama, K. Nakamura, S. Ueno.
    • Organizer
      第44回日本脳科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小中学生におけるインターネット依存傾向と内在化・外在化問題・ASD/ADHD特性との関連2017

    • Author(s)
      足立匡基・髙橋芳雄・栗林理人・斉藤まなぶ・中村和彦
    • Organizer
      第44回日本脳科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 幼児期から成人期にかけてのブローカ野における灰白質体積の発達2017

    • Author(s)
      髙橋芳雄 松井三枝 中村和彦
    • Organizer
      第44回日本脳科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 視線検出装置(Gazefinder)を用いた5歳児のASD傾向の検討2017

    • Author(s)
      斉藤まなぶ、土屋賢治、吉田和貴、足立匡基、髙橋芳雄、下山修司、山田 順子、上野 伸哉、中村 和彦
    • Organizer
      第44回日本脳科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 自閉スペクトラム症児者の理解2017

    • Author(s)
      中村和彦
    • Organizer
      2017年度 一般社団法人日本LD学会 公開シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 自閉スペクトラム症児者のライフステージに応じた“つながる”支援(シンポジ ウム)2017

    • Author(s)
      中村和彦
    • Organizer
      2017年度 一般社団法人日本LD学会 公開シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Phospholipase C-related inactive protein type-1 is involved in intravenous anesthetic-induced EEG changes in mice.2017

    • Author(s)
      Y. Nikaido, T. Furukawa, S. Shimoyama, T. Kushikata, K. Hirota, T. Kanematsu, M. Hirata, S. Ueno.
    • Organizer
      第40回神経科学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The effect of chronic diazepam administration on Lcn2 expression and spine morphology.2017

    • Author(s)
      T. Furukawa, S. Shimoyama, Y. Nikaido, Y. Miki, K. Koga, K. Nakamura, K. Wakabayashi, S. Ueno.
    • Organizer
      第40回神経科学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 視線検出装置(Gazefinder)を用いたASD早期診断の有用性の検討2017

    • Author(s)
      斉藤まなぶ、大里絢子、坂本由唯、吉田和貴、柞木田なつみ、松原侑里、吉田恵心、足立匡基、高橋芳雄、安田小響、栗林理人、中村和彦
    • Organizer
      第154回弘前医学会例会
    • Place of Presentation
      弘前大学医学部コミュニケーションセンター(青森県・弘前市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] IGF-1を標的とした自閉症スペクトラム治療薬候補の探索2017

    • Author(s)
      下山修司
    • Organizer
      第4回 脳研×高度先進×COI合同セミナー
    • Place of Presentation
      弘前大学(青森県・弘前市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Gaze Fixation Patterns in Children With Autism Spectrum Disorder and Typical Development Screening From the Japanese Community Based 5-Year-Old Children2016

    • Author(s)
      Kazuhiko Nakamura, Manabu Saito
    • Organizer
      The 55th American College of Neuropsychopharmcology (ACNP)
    • Place of Presentation
      アメリカ フロリダ
    • Year and Date
      2016-12-04
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prevalence and Comorbidities of DCD Using DSM-5, Comparison of Mortor and Cognitive function at Preschool Age in a Japanese Community.2016

    • Author(s)
      Kazutaka Yoshida, Manabu Saito, Junko Yamada, Shinya Ueno, Kazuhiko Nakamura
    • Organizer
      2016 International Symposium on Neurodegenerative Diseases & the 43rd Annual Conference of Japan Brain Science Society
    • Place of Presentation
      中国 西安
    • Year and Date
      2016-11-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] スクリーニングツールに基づく児童思春期におけるASD有病率の推計およびASD傾向と適応状態の関連2016

    • Author(s)
      足立匡基、高栁伸哉、安田小響、吉田恵心、栗林理人、大里絢子、斉藤まなぶ、中村和彦
    • Organizer
      第57回 日本児童青年精神医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] GazeFinder(Ka-o-TV)を用いた5歳児のASD特性の検討2016

    • Author(s)
      斉藤まなぶ、大里絢子、吉田恵心、高柳伸哉、足立匡基、安田小響、田中勝則、増田貴人、栗林理人、中村和彦
    • Organizer
      第57回 日本児童青年精神医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 某市5歳児発達健診から見た運動機能と認知機能の関係2016

    • Author(s)
      大里絢子、斉藤まなぶ、坂本由唯、吉田恵心、高柳伸哉、足立匡基、安田小響、田中勝則、増田貴人、栗林理人、中村和彦
    • Organizer
      第57回 日本児童青年精神医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 短縮版感覚プロファイルを用いた子どもの感覚の特異性と発達障害特性の関連2016

    • Author(s)
      安田小響、、足立匡基、斉藤まなぶ、大里絢子、吉田恵心、栗林理人、増田貴人、高栁伸哉、田中勝則、中村和彦
    • Organizer
      第57回 日本児童青年精神医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 発達性協調運動障害への保護者・先生の気づきに関する検討2016

    • Author(s)
      三上美咲、斉藤まなぶ、増田貴人、田中勝則、大里絢子、坂本由唯、吉田恵心、高柳伸哉)、足立匡基、安田小響、栗林理人、中村和彦
    • Organizer
      第57回 日本児童青年精神医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 5歳児の自閉スペクトラム障害における VLDL、IGF-1、オキシトシンの診断有用性の検討2016

    • Author(s)
      斉藤 まなぶ 、 下山 修司 、 吉田 恵心 、坂本 由唯 、大里 絢子 、 高柳 伸哉 、 足立 匡基 、 安田 小響 、 栗林 理人 、 中村 和彦
    • Organizer
      第112回 日本精神神経学会総会
    • Place of Presentation
      幕張メッセ(千葉県・千葉市)
    • Year and Date
      2016-06-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] 遺伝子Tspo の発現調節メカニズムの解明2016

    • Author(s)
      下山修司、中村和彦、上野伸哉
    • Organizer
      日本生化学会 東北支部 第82回例会
    • Place of Presentation
      弘前大学(青森県・弘前市)
    • Year and Date
      2016-05-21
    • Related Report
      2016 Annual Research Report
  • [Presentation] Brain Dopamine D1 Receptor Binding in Young Adults with Autism Spectrum Disorder2016

    • Author(s)
      K. Suzuki, K. Nakamura, Y. Ouchi, K. Takebayashi, M. Yokokura, K. Nakaizumi, M. Tsujii, T. Sugiyama and N. Mori
    • Organizer
      2016 International Meeting for Autism Research
    • Place of Presentation
      アメリカ ボルティモア
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Applicability of the Autism Spectrum Screening Questionnaire Parent Form to 5-Ye+C8:C13ar-Old Children2016

    • Author(s)
      M. Adachi, N. Takayanagi, S. Yasuda, S. Yoshida, M. Kuribayashi, A. Osato, T. Masuda, M. Tanaka, M. Saito and K. Nakamura
    • Organizer
      2016 International Meeting for Autism Research
    • Place of Presentation
      アメリカ ボルティモア
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Risk and Protective Factors of Depression in Children with ASD Tendency in Japan.2016

    • Author(s)
      N. Takayanagi, M. Adachi, S. Yasuda, S. Yoshida, M. Kuribayashi and K. Nakamura
    • Organizer
      2016 International Meeting for Autism Research
    • Place of Presentation
      アメリカ ボルティモア
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CNV Analysis and Exome Sequencing in Japanese Autism Spectrum Disorder Subjects2016

    • Author(s)
      K. Nakamura, I. Thanseem, M. Tsujii and N. Matsumoto
    • Organizer
      2016 International Meeting for Autism Research
    • Place of Presentation
      アメリカ ボルティモア
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prevalence of Autism Spectrum Disorder in a Japanese Community-Based Population Sample of Five-Year-Old Children2016

    • Author(s)
      M. Saito, N. Takayanagi, M. Adachi, A. Osato, S. Yasuda, T. Masuda, M. Tanaka, S. Yoshida, M. Kuribayashi and K. Nakamura
    • Organizer
      2016 International Meeting for Autism Research
    • Place of Presentation
      アメリカ ボルティモア
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 5歳児発達健診における発達障害の疫学2016

    • Author(s)
      坂本由唯、斉藤まなぶ、中村和彦
    • Organizer
      第153回弘前医学会例会
    • Place of Presentation
      弘前大学医学部コミュニケーションセンター(青森県弘前市)
    • Year and Date
      2016-01-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] CNV Analysis and Exome Sequencing in Japanese Autism Spectrum Disorder Subjects2015

    • Author(s)
      K. Nakamura, I. Thanseem, N. Mori, M. Tsujii and N. Matsumoto
    • Organizer
      54th Annual Meeting of the American College of Neuropsychopharmacology
    • Place of Presentation
      フロリダ ハリウッド(アメリカ)
    • Year and Date
      2015-12-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 某市5歳児発達健診における発達性協調運動障害の疫学2015

    • Author(s)
      斉藤まなぶ、山田順子、下山修司、尾崎拓、上野伸哉、中村和彦
    • Organizer
      第42回日本脳科学会
    • Place of Presentation
      ANAホリデイ・イン リゾート宮崎 (宮崎県宮崎市)
    • Year and Date
      2015-11-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] 成人期ADHDの脳内における活性化ミクログリア2015

    • Author(s)
      竹林淳和、中村和彦、尾内康臣、横倉正倫、岩田泰秀、森則夫
    • Organizer
      第42回日本脳科学会
    • Place of Presentation
      ANAホリデイ・イン リゾート宮崎 (宮崎県宮崎市)
    • Year and Date
      2015-11-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] 新規SERT制御因子としてのNSF~自閉症発現メカニズムへの関与~2015

    • Author(s)
      岩田圭子、松﨑秀夫、立花太郎、中村和彦、片山泰一、森則夫
    • Organizer
      第42回日本脳科学会
    • Place of Presentation
      ANAホリデイ・イン リゾート宮崎 (宮崎県宮崎市)
    • Year and Date
      2015-11-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] 某市5歳児発達健診における発達障害の疫学2015

    • Author(s)
      斉藤まなぶ、大里絢子、中村和彦
    • Organizer
      第56回日本児童青年精神医学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-09-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] S3-1シンポジウム3発達障害の課題解決に向けた基礎・臨床研究の連携 【演題名:5歳児発達健診における発達障害の疫学】2015

    • Author(s)
      中村和彦
    • Organizer
      第45回日本神経精神薬理学会第37回日本生物学的精神医学会合同年会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Epidemiology of Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder in a community-based population sample of five-year olds children2015

    • Author(s)
      K. Nakamura,M.Saito, A. Kaneda-Osato, M.Tanaka,T.Masuda,N.Takayanagi, S.Yasuda, M.Adachi,Y.Sakamoto,S.Yoshida,M.Kuribayashi
    • Organizer
      The 8th Congress of The Asian Society for Child and Adolescent Psychiatry and Allied Professions
    • Place of Presentation
      クアラルンプール(マレーシア)
    • Year and Date
      2015-08-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 某市5歳児発達健診におけるWISC-IVの下位項目の検討2015

    • Author(s)
      大里絢子、斉藤まなぶ、増田貴人、田中勝則、中村和彦
    • Organizer
      第17回東北児童青年精神医学会
    • Place of Presentation
      弘前大学医学部コミュニケーションセンター(青森県弘前市)
    • Year and Date
      2015-06-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 小中学生における抑うつの保護・悪化要因2015

    • Author(s)
      足立匡基、高柳伸哉、安田小響、吉田恵心、栗林理人、中村和彦
    • Organizer
      第17回東北児童青年精神医学会
    • Place of Presentation
      弘前大学医学部コミュニケーションセンター(青森県弘前市)
    • Year and Date
      2015-06-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] Epidemiology of autism spectrum disorder and attention deficit hyperactivity disorder in a community-based population sample of five-year olds children2015

    • Author(s)
      M. Saito, A. Kaneda-osato, M. Tanaka, T. Masuda, N. Takayanagi,S. Yasuda, K. Nakamura
    • Organizer
      16th International Congress of ESCAP European Society for Child and Adolescent Psychiatry
    • Place of Presentation
      マドリード(スペイン)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of Genomic Copy Number Variations and Exome Sequencing in Japanese Autism Spectrum Disorder Subjects2015

    • Author(s)
      K. Nakamura, I. Thanseem, N. Mori, M. Tsujii and N. Matsumoto,
    • Organizer
      14th the International Meeting for Autism Research (IMFAR) Annual Meeting
    • Place of Presentation
      ソルトレークシティー(アメリカ)
    • Year and Date
      2015-05-13
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Abnormal Expression of a SERT-Binding Protein, NSF, in Autism: Implications for Pathophysiology in Autism2015

    • Author(s)
      K. Iwata, H. Matsuzaki, K. Nakamura, T. Katayama and N. Mori
    • Organizer
      14th the International Meeting for Autism Research(IMFAR) Annual Meeting
    • Place of Presentation
      ソルトレークシティー(アメリカ)
    • Year and Date
      2015-05-13
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Book] 大人のADHD臨床 アセスメントから治療まで2016

    • Author(s)
      中村 和彦(編著)、
    • Total Pages
      196
    • Publisher
      金子書房
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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