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Enhancement of Cognitive Behavioral therapy for anxiety disorders and posttraumatic stress disorder by bright light exposure

Research Project

Project/Area Number 15H04897
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionShiga University of Medical Science

Principal Investigator

Kuriyama Kenichi  滋賀医科大学, 医学部, 客員教授 (00415580)

Co-Investigator(Kenkyū-buntansha) 吉池 卓也  滋賀医科大学, 医学部, 助教 (40647624)
高橋 正洋  滋賀医科大学, 医学部, 講師 (30548194)
松尾 雅博  滋賀医科大学, 医学部, 講師 (70456838)
吉村 篤  滋賀医科大学, 医学部, 講師 (90522079)
栗本 直樹  滋賀医科大学, 医学部, 助教 (20567078)
稲垣 貴彦  滋賀医科大学, 医学部, 助教 (20535348)
田中 恒彦  滋賀医科大学, 医学部, 特任助教 (60589084)
Research Collaborator KOIZUMI hazuki  
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2018: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Keywords神経科学 / 生理学 / 高照度光 / 精神医学 / 認知行動療法
Outline of Final Research Achievements

Trait anxiety scores assessed by the State-Trait Anxiety Inventory (STAI) showed greater decrement after receiving an exposure-based cognitive behavioral therapy (EB-CBT) in patients with panic disorder or posttraumatic stress disorder (PTSD) exposed 8000-lux bright light (15 min per session) than 800-lux usual light during each EB-CBT session. Owing to the small sample size, the decrement rate in trait anxiety score did not achieve a statistically significant difference, but it showed a trend toward significance. On the other hand, State anxiety scores assessed by the STAI seemed not to be affected by the bright light exposure.

Academic Significance and Societal Importance of the Research Achievements

パニック障害等の不安障害および外傷後ストレス障害(PTSD)の病態基盤に、恐怖条件づけ学習が関連していることが推測されており、暴露主体型認知行動療法(EB-CBT)はこの恐怖条件づけを消去する学習過程を含むことが示されている。本研究成果は、高照度光照射がEB-CBTによる治療効果を増強する可能性を示唆しており、これにより不安障害、PTSDの治療転帰を改善する可能性および、治療に伴う人的コストの低減、治療中の患者負担の軽減に寄与する可能性が推測される。また本成果は、不安障害の生理学的病態理解、ヒトの恐怖関連学習過程の理解を深めることにも寄与する。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (68 results)

All 2018 2017 2016 2015

All Journal Article (24 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 9 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (39 results) (of which Int'l Joint Research: 18 results,  Invited: 6 results) Book (5 results)

  • [Journal Article] Evidence for the Efficacy of Bright Light Therapy for Bipolar Depression2018

    • Author(s)
      Benedetti Francesco、Avery David H.、Bauer Michael、Bunney William E.、Caliyurt Okan、Camardese Giovanni、Colombo Cristina、Dallaspezia Sara、Henriksen Tone Elise、Kasper Siegfried、Kuriyama Kenichi、et al.
    • Journal Title

      American Journal of Psychiatry

      Volume: 175 Issue: 9 Pages: 905-906

    • DOI

      10.1176/appi.ajp.2018.18020231

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of bright light exposure on human fear conditioning, extinction, and associated prefrontal activation2018

    • Author(s)
      Yoshiike Takuya、Honma Motoyasu、Yamada Naoto、Kim Yoshiharu、Kuriyama Kenichi
    • Journal Title

      Physiology & Behavior

      Volume: 194 Pages: 268-276

    • DOI

      10.1016/j.physbeh.2018.06.015

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 成人不眠症の背景にある心理行動学的要因.2018

    • Author(s)
      長尾賢太朗、栗山健一
    • Journal Title

      精神医学

      Volume: 60 Pages: 973-981

    • Related Report
      2018 Annual Research Report
  • [Journal Article] 不安障害の不眠治療はいかにあるべきか.2018

    • Author(s)
      眞田陸、栗山健一
    • Journal Title

      精神神経学雑誌

      Volume: 120(7) Pages: 577-583

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] うつ病を伴う不眠症治療-適正処方を見据えた薬剤の選択と使い方.2018

    • Author(s)
      山本彬、栗山健一
    • Journal Title

      Depression Strategy

      Volume: 8 Pages: 7-11

    • Related Report
      2018 Annual Research Report
  • [Journal Article] PTSD治療奏効率向上のためのストレスマネジメント2018

    • Author(s)
      長尾賢太朗、河村葵、栗山健一
    • Journal Title

      臨床精神薬理

      Volume: 21 Pages: 479-487

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Effects of bedtime periocular and posterior cervical cutaneous warming on sleep status in adult male subjects: a preliminary study2017

    • Author(s)
      Igaki Michihito、Suzuki Masahiro、Sakamoto Ichiro、Ichiba Tomohisa、Kuriyama Kenichi、Uchiyama Makoto
    • Journal Title

      Sleep and Biological Rhythms

      Volume: 16 Issue: 1 Pages: 77-84

    • DOI

      10.1007/s41105-017-0129-3

    • NAID

      40021436084

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Bedtime Periocular Warming on Sleep Status in Adult Female Subjects: A Pilot Study2017

    • Author(s)
      Sakamoto Ichiro、Igaki Michihito、Ichiba Tomohisa、Suzuki Masahiro、Kuriyama Kenichi、Uchiyama Makoto
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2017 Issue: 1 Pages: 1-5

    • DOI

      10.1155/2017/6419439

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Changes in the symptom frequency of repid eye movement sleep behavior disorder according to disease duration.2017

    • Author(s)
      Sumi Y, Matsuo M, Nakabayashi T, Masuda F, Takahashi M, Kanemura T, Kuriyama K, Yamada N, Takami M, Kadotani H
    • Journal Title

      Sleep Science and Practice

      Volume: 1 Pages: 16-16

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] COMT genotype is associated with plasticity in sense of body ownership:a pilot study2017

    • Author(s)
      Honma M, Yosiike T, Ikeda K, Kuriyama K
    • Journal Title

      Psychological Research

      Volume: in press Issue: 3 Pages: 634-644

    • DOI

      10.1007/s00426-017-0849-7

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] ストレス因関連障害および不安障害に併存する不眠.2017

    • Author(s)
      河村葵、長尾賢太朗、栗山健一
    • Journal Title

      ねむりとマネージメント

      Volume: 4 Pages: 5-9

    • Related Report
      2017 Annual Research Report
  • [Journal Article] うつ病患者の為の連携の在り方~精神科へ紹介するポイント~.2017

    • Author(s)
      栗山健一
    • Journal Title

      大津市医師会誌

      Volume: 4 Pages: 19-23

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 大災害と不眠.2017

    • Author(s)
      中林孝夫、栗山健一
    • Journal Title

      精神医学

      Volume: 59 Pages: 559-565

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 高齢不眠症患者への非薬物療法.2017

    • Author(s)
      角幸頼、栗山健一
    • Journal Title

      PharmaMedica

      Volume: 35 Pages: 35-38

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 睡眠薬.2017

    • Author(s)
      栗山健一
    • Journal Title

      新薬展望

      Volume: l53(S-1) Pages: 526-560

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 睡眠薬2017

    • Author(s)
      栗山健一
    • Journal Title

      新薬展望2017

      Volume: 153(S-1) Pages: 526-530

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 高齢不眠症患者への非薬物療法2017

    • Author(s)
      角幸頼、栗山健一
    • Journal Title

      PharmaMedica

      Volume: 35(3) Pages: 35-38

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 睡眠における記憶と脳機能2016

    • Author(s)
      栗山健一
    • Journal Title

      Depression Strategy

      Volume: 6(1) Pages: 5-8

    • NAID

      40020781807

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
  • [Journal Article] 睡眠と記憶および感情調節機能2016

    • Author(s)
      栗山健一
    • Journal Title

      精神医学

      Volume: 58(6) Pages: 461-468

    • NAID

      40020853126

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 精神・認知に宿る体内時計機能2016

    • Author(s)
      栗山健一
    • Journal Title

      BIO Clinica

      Volume: 31(9) Pages: 18-21

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 睡眠中の学習機能2016

    • Author(s)
      栗山健一
    • Journal Title

      Anet

      Volume: 20(2) Pages: 9-13

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 恐怖・情動記憶と睡眠2016

    • Author(s)
      栗山健一
    • Journal Title

      ねむりとマネージメント

      Volume: 3(2) Pages: 10-15

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Sleep-independent offline consolidation of response inhibition during the daytime post-training period.2015

    • Author(s)
      Honma M, Yoshiike T, Ikeda H, Kuriyama K
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 10362-10362

    • DOI

      10.1038/srep10362

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] D-サイクロセリンおよびパルプロ酸による恐怖再燃の予防効果2015

    • Author(s)
      栗山健一
    • Journal Title

      日本生物学的精神医学会誌

      Volume: 26(3) Pages: 161-167

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] Sleep deprivation triggers shared temporal dynamics of time and mood perception in bipolar depression.2018

    • Author(s)
      Yoshiike T, Dallaspezia S, Kuriyama K, Yamada N, Colombo C, Benedetti F
    • Organizer
      24th Congress of the European Sleep Research Society
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Electrophysiological correlates of antidepressant response to sleep deprivation: preliminary findings by using a 1-ch EEG device.2018

    • Author(s)
      Yoshiike T, Suzuki M, Dallaspezia S, Kashiwagi K, Kuriyama K, Uchiyama M, Colombo C, Benedetti F
    • Organizer
      2018 Joint Meeting of the ECNS, the ISNIP, the ISBET and the ISFSI
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bright light exposure triggers earlier onset of selective consolidation of motor-skill accuracy in humans.2018

    • Author(s)
      Yoshiike T, Honma M, Yamada N, Kuriyama K
    • Organizer
      Society of Light Treatment and Biological Rhythms
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Shared temporal dynamics of time and mood perception in response to sleep deprivation in bipolar depression.2018

    • Author(s)
      Yoshiike T, Dallaspezia S, Kuriyama K, Yamada N, Colombo C, Benedetti F
    • Organizer
      The 9th Congress of Asian Sleep Research Society
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] REM sleep behavior disorder; Coincidental appearance and possible pathological link to post-polio syndrome.2018

    • Author(s)
      Nagao k, Shimizu Y, Sumi Y, Nakabayashi T, Takami M, Matsuo M, Kuriyama K, Kadotani H
    • Organizer
      The 9th Congress of Asian Sleep Research Society
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Practical use of a single channel sleep EEG for diagnosis of Major Depressive Disorder -Multicenter exploratory prospective study (SEEDs)-.2018

    • Author(s)
      Kuriyama K, Suzuki M, Kadotani H, Yoshimura A, Yoshinaka H, Yamanaka M, Tsuboi H, Ueda T, Mori A, Kashiwagi K, Yoshida M, Omori T, Kutsumi H, Uchiyama M, Yamada N
    • Organizer
      Sleep 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 地域包括・多職種連携における睡眠医療に携わる医師・医療機関の関わり2018

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] PSGパラメターとうつ病との関連2018

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 不眠症病態における睡眠状態誤認の位置づけ2018

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 睡眠脳波を用いたうつ病診断補助システムの開発2018

    • Author(s)
      栗山健一、鈴木正泰、角谷寛、吉中勇人、山中真由美、森梓、大森崇、久津見弘、柏木香保里、吉田政樹、内山真、山田尚登
    • Organizer
      第114回日本精神神経学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 再発を繰り返すうつ病に対するメンテナンスECTと再発する要因2018

    • Author(s)
      栗本直樹、栗山健一、山田尚登
    • Organizer
      第114回日本精神神経学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] A research project aimed at developing practical use of sleep EEG for diagnosis of major depressive disorder:Multicenter exploratory prospective study.2017

    • Author(s)
      Kuriyama K, Suzuki M, Kadotani H, Yoshinaka H, Yamanaka M, Omori T, Mori A, Tsuboi H, Ueda T, Kashiwagi K, Yoshimura A, Yoshiike T, Takahashi M, Matsuo M, Morita S, Takami M, Fujii Y, Nakabayashi T, Kubo H, Yokose H, Yamada K, Furihara R, Yoshida M, Kutsumi H, Uchiyama M, Yamada N
    • Organizer
      Japanese-American-German Frontiers of Science Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A research project aimed at developing practical use of sleep EEG for diagnosis of major depressive disorder:Multicenter exploratory prospective study.2017

    • Author(s)
      Kuriyama K, Suzuki M, Kadotani H, Yoshinaka H, Yamanaka M, Omori T, Mori A, Tsuboi H, Ueda T, Kashiwagi K, Yoshimura A, Yoshiike T, Takahashi M, Matsuo M, Morita S, Takami M, Fujii Y, Nakabayashi T, Kubo H, Yokose H, Yamada K, Furihara R, Yoshida M, Kutsumi H, Uchiyama M, Yamada N.
    • Organizer
      World Sleep 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Decrease of dopamine transporter correlates cognitive decline in rapid eye movement behavior disorder patients.2017

    • Author(s)
      Sumi Y, Matsuo M, Takao N, Kuriyama K, Yamada N, Kadotani H
    • Organizer
      World Sleep 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Insomnia as a somatic representation of anxiety in the symptomatology of depression.2017

    • Author(s)
      Yoshiike T, kuriyama K
    • Organizer
      World Sleep 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bright light enhances precocious expression of motor skill consolidation while optimizing speed-accuracy trade-off in humans.2017

    • Author(s)
      Yoshiike T, Honma M, Kuriyama K
    • Organizer
      13th World Congress of Biological Psychiatry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The role for insomnia and somatic anxiety in the symptomatology and pharmacotherapy in remitted depression.2017

    • Author(s)
      Yoshiike T, Nakasato Y, Kuriyama K, Nakamura M
    • Organizer
      13th World Congress of Biological Psychiatry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Grief shares circuits with pleasantness: Subliminal grief priming activates the orbitofrontal cortex to boost empathic pain.2017

    • Author(s)
      Yoshiike T, Kuriyama K, Ikeda H, Ohmura H, Honma M, Moriguchi Y, Asano K, Kim Y, Nakajima S
    • Organizer
      13th World Congress of Biological Psychiatry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 難治性大うつ病性障害がECT後に再発する理由2017

    • Author(s)
      栗本直樹、栗山健一、角谷寛、山田尚登
    • Organizer
      第30回日本総合病院精神医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] うつ病と不眠再考2017

    • Author(s)
      栗山健一
    • Organizer
      第30回日本総合病院精神医学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] PTSD・不安障害の根治療法2017

    • Author(s)
      栗山健一
    • Organizer
      第121回近畿精神神経学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 睡眠中の神経可塑性がうつ病病態へ及ぼす影響2017

    • Author(s)
      栗山健一
    • Organizer
      第14回日本うつ病学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 高照度光を用いた治療抵抗性うつ病治療2017

    • Author(s)
      栗山健一
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 不安障害の不眠治療は如何にあるべきか2017

    • Author(s)
      栗山健一
    • Organizer
      第113回日本精神神経学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 認知症と不眠、睡眠薬との関連2016

    • Author(s)
      栗山健一
    • Organizer
      第21回日本診療内科学会総会・学術大会
    • Place of Presentation
      奈良春日野国際フォーラム
    • Year and Date
      2016-12-03
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] The role emotional memory consolidation in the pathophysiologies of anxiety and depression:a potential target for chronotherapeutics2016

    • Author(s)
      吉池卓也、栗山健一
    • Organizer
      第23回日本時間生物学会学術大会
    • Place of Presentation
      名古屋大学 豊田講堂
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] 複雑性悲嘆においてサブリミナル悲嘆刺激は共感性疼痛を促進する2016

    • Author(s)
      吉池卓也、中島聡美、本間元康、池田大樹、大村英史、淺野敬子、金吉晴、守口善也、栗山健一
    • Organizer
      第38回日本生物学的精神医学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] 睡眠中の情動記憶消去学習2016

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会 第41回定期学術集会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2016-07-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 不安障害の不眠治療はいかにあるべきか2016

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会 第41回定期学術集会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2016-07-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 不眠症治療におけるリラクゼーション・体温調節の科学的効果2016

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会 第41回定期学術集会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2016-07-07
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高照度光による手続き記憶強化プロセスの検討2016

    • Author(s)
      吉池卓也、本間元康、池田大樹、栗山健一
    • Organizer
      日本睡眠学会 第41回定期学術集会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2016-07-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 睡眠とアミロイドβ代謝:睡眠薬と認知症の関連性2016

    • Author(s)
      栗山健一
    • Organizer
      第112回日本精神神経学会学術総会
    • Place of Presentation
      千葉 幕張メッセ
    • Year and Date
      2016-06-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] Current Situation of Cooperation between Mental Health Services and Police in Shiga Prefecture, Japan2016

    • Author(s)
      Inagaki T, Nakabayashi T, Tanaka T, Kuriyama K, Yamada N
    • Organizer
      The 5th European Association for Forensic Child and Adolescent Psychiatry Congress
    • Place of Presentation
      Porto, Portugal
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bright Light Augments Fear Extinction and Reconstructs Prefrontal Neuroircuitry to Further Regulate Fear in Humans.2015

    • Author(s)
      Yoshiike T, Honma M, Kim Y, Kuriyama K
    • Organizer
      Worldsleep 2015
    • Place of Presentation
      Istanbul Turkey
    • Year and Date
      2015-10-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Valproic acid but not D-cycloserine facilitates sleep-dependent offline learning of extinction of conditioned fear in humans.2015

    • Author(s)
      Kuriyama K, Yoshiike T, Kim Y
    • Organizer
      Worldsleep 2015
    • Place of Presentation
      Istanbul Turkey
    • Year and Date
      2015-10-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] なぜPTSD有病率は女性が高いのか-トラウマ記憶の考察より2015

    • Author(s)
      栗山健一
    • Organizer
      日本女性心身医学会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-26
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Bright Light Facilitates Fear Extinction and Prefrontal Processing for Fear Extinction in Humans.2015

    • Author(s)
      Yoshiike T, Honma M, Kim Y, Kuriyama K
    • Organizer
      27th Annual Meeting of Society of Light Treatment and Biological Rhythms (SLTBR) 2015
    • Place of Presentation
      San Diego USA
    • Year and Date
      2015-06-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] トレス性障害・不安障害の認知行動療法効果促進のための睡眠・認知改善薬2015

    • Author(s)
      栗山健一
    • Organizer
      日本睡眠学会第40回定期学術集会
    • Place of Presentation
      宇都宮
    • Year and Date
      2015-06-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effect of D-cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses.2015

    • Author(s)
      Kuriyama K, Yoshiike T, Kim Y
    • Organizer
      WPA REGIONAL CONGRESS
    • Place of Presentation
      OSAKA Japan
    • Year and Date
      2015-05-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Book] 治療薬UP-TO-DATE 20172017

    • Author(s)
      西泰孝、栗山健一、山田尚登
    • Total Pages
      1248
    • Publisher
      メディカルレビュー社
    • Related Report
      2016 Annual Research Report
  • [Book] ガイドライン外来診療20172017

    • Author(s)
      藤井勇佑、栗山健一
    • Total Pages
      650
    • Publisher
      日経メディカル開発
    • Related Report
      2016 Annual Research Report
  • [Book] DSM-5スタディガイド1冊で身につく診断と面接の技法2016

    • Author(s)
      栗山健一
    • Total Pages
      408
    • Publisher
      医学書院
    • Related Report
      2016 Annual Research Report
  • [Book] 睡眠科学2016

    • Author(s)
      栗山健一
    • Total Pages
      344
    • Publisher
      化学同人
    • Related Report
      2016 Annual Research Report
  • [Book] The Comprehensive Guide to Post-Traumatic Stress Disorders2016

    • Author(s)
      Yoshiike T, Kuriyama K
    • Publisher
      Springer
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2020-03-30  

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