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Evaluation of fertility preservation and perspective on prognostic prediction using both functional and morphological MR imaging

Research Project

Project/Area Number 15H04905
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKyoto University

Principal Investigator

TOGASHI Kaori  京都大学, 医学研究科, 教授 (90135484)

Co-Investigator(Kenkyū-buntansha) 木戸 晶  京都大学, 医学研究科, 助教 (80595710)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Keywords婦人科画像診断 / MRI / 子宮蠕動 / 子宮頸癌 / 子宮体癌 / 子宮機能 / 妊孕能
Outline of Final Research Achievements

Recently, fertility preserved treatment and personalized treatment are highly required. In the field of gynecologic diagnostic imaging, our objectives were as follows: 1)construction of uterine functional evaluation using MRI, 2) Diagnosis of gynecologic malignancy by both morphological and functional imaging, including perspective on prognostic prediction, 3) new MR imaging contrast and construction of MR parameters. As a results, we could get the factors that improve diagnostic accuracy for gynecologic cancer and factors that will predict patients’ prognosis. Those results may lead to multicenter study for getting for useful information for both patients and physicians.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (23 results)

All 2018 2017 2016 2015

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (8 results) (of which Int'l Joint Research: 7 results,  Invited: 8 results)

  • [Journal Article] Differentiation of Seromucinous Borderline Tumor from Serous Borderline Tumor on MR Imaging2018

    • Author(s)
      Kurata Y, Kido A, Moribata Y, Kameyama K, Minamiguchi S, Konishi I, Togashi K
    • Journal Title

      Magnetic Resonance in Medical Sciences

      Volume: 17 Issue: 3 Pages: 211-217

    • DOI

      10.2463/mrms.mp.2017-0055

    • NAID

      130007403774

    • ISSN
      1347-3182, 1880-2206
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MRI findings of chronic abruption-oligohydramnios sequence (CAOS): report of three cases2017

    • Author(s)
      Kurata Y, Kido A, Minamiguchi S, Kondoh E, Togashi K
    • Journal Title

      Abdom Radiol (NY)

      Volume: 42 Issue: 7 Pages: 1839-1844

    • DOI

      10.1007/s00261-017-1141-4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] What is the most suitable MR signal index for quantitative evaluation of placental function using Half-Fourier acquisition single-shot turbo spin-echo compared with T2-relaxation time?2017

    • Author(s)
      Kameyama KN, Kido A, Himoto Y, Moribata Y, Minamiguchi S, Konishi I, Togashi K.
    • Journal Title

      Acta Radiologica

      Volume: 印刷中 Issue: 6 Pages: 748-754

    • DOI

      10.1177/0284185117727786

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MR imaging of uterine morphology and dynamic changes during lactation.2017

    • Author(s)
      Daido S, Kido A, Kataoka M, Nakai A, Fujimoto K, Kusahara H, Okada T, Togashi K
    • Journal Title

      J Magn Reson Imaging

      Volume: 45 Issue: 2 Pages: 617-623

    • DOI

      10.1002/jmri.25375

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Uterine peristalsis and junctional zone:correlation with age and postmenopausal status.2017

    • Author(s)
      Kiguchi K, Kido A, Kataoka M, Shitano F, Fujimoto K, Himoto Y, Moribata Y,Kurata Y, Fushimi Y, Okada T, Togashi K
    • Journal Title

      Acta Radiol

      Volume: 58 Issue: 2 Pages: 224-231

    • DOI

      10.1177/0284185116639768

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Internal evaluation ofimpregnation treatment of waterlogged wood; relation between concentration ofinternal materials and relaxation time using magnetic resonance imaging.2017

    • Author(s)
      Kanazawa Y, Yamada T, Kido A, Fujimoto K, Takakura K, Hayashi H, Fushimi Y,Kozawa S, Koizumi K, Okuni M, Ueda N, Togashi K
    • Journal Title

      Magn Reson Imaging

      Volume: 38 Pages: 196-201

    • DOI

      10.1016/j.mri.2017.01.010

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Feasibility of Computed Diffusion Weighted Imaging and Optimization of b-value in Cervical Cancer2017

    • Author(s)
      Moribata Y, Kido A, Fujimoto K, Himoto Y, Kurata Y, Shitano F, Kiguchi K,Konishi I, Togashi K
    • Journal Title

      Magnetic Resonance in Medical Sciences

      Volume: 16 Issue: 1 Pages: 66-72

    • DOI

      10.2463/mrms.mp.2015-0161

    • NAID

      130005286864

    • ISSN
      1347-3182, 1880-2206
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diagnostic performance of MR imaging findings and quantitative values in the differentiation of seromucinous borderline tumour from endometriosis-related malignant ovarian tumour.2016

    • Author(s)
      Kurata Y, Kido A, Moribata Y, Kameyama K, Himoto Y, Minamiguchi S, Konishi I,Togashi K
    • Journal Title

      Eur Radiol

      Volume: -

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimization of non-contrast-enhanced MR angiography of the renal artery with three-dimensional balanced steady-state free-precession and time-spatial labeling inversion pulse (time-SLIP) at 3T MRI, in relation to age and blood velocity.2016

    • Author(s)
      Kurata Y, Kido A, Fujimoto K, Kiguchi K, Takakura K, Moribata Y, Shitano F,Himoto Y, Fushimi Y, Okada T, Togashi K.
    • Journal Title

      Abdom Radiol (NY)

      Volume: 41 Issue: 1 Pages: 119-126

    • DOI

      10.1007/s00261-015-0608-4

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of uterine peristalsis using cine MRI on the coronal plane in comparison with the sagittal plane.2016

    • Author(s)
      Shitano F, Kido A, Kataoka M, Fujimoto K, Kiguchi K, Fushimi Y, Togashi K.
    • Journal Title

      Acta Radiol

      Volume: 57 Issue: 1 Pages: 122-127

    • DOI

      10.1177/0284185115579080

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Placental function assessed visually using half-Fourier acquisition single-shot turbo spin-echo (HASTE) magnetic resonance imaging.2016

    • Author(s)
      Himoto Y, Kido A, Mogami H, Moribata Y, Minamiguchi S, Shitano F, Kiguchi K,Kurata Y, Konishi I, Togashi K.
    • Journal Title

      Placenta

      Volume: 39 Pages: 55-60

    • DOI

      10.1016/j.placenta.2016.01.007

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of pseudomyxoma peritonei: visualization of septa using diffusion-weighted images with low b values.2016

    • Author(s)
      Himoto Y, Kido A, Fujimoto K, Kawada K, Kitai T, Sakai Y, Togashi K.
    • Journal Title

      Abdom Radiol (NY)

      Volume: 印刷中

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MR appearance of normal uterine endometrium considering menstrual cycle: differentiation with benign and malignant endometrial lesions.2016

    • Author(s)
      Shitano F, Kido A, Kataoka M, Fujimoto K, Kiguchi K, Fushimi Y, Konishi I,Togashi K.
    • Journal Title

      Acta Radiol

      Volume: 印刷中

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Layer of Decreased Apparent Diffusion Coefficient at the Endometrial-Myometrial Junction in Uterine Adenomyosis.2016

    • Author(s)
      Kido A, Fujimoto K, Matsubara N, Kataoka M, Konishi I, Togashi K.
    • Journal Title

      Magn Reson Med Sci

      Volume: 印刷中

    • NAID

      130005144169

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subendometrial enhancement and peritumoral enhancement for assessing endometrial cancer on dynamic contrast enhanced MR imaging.2015

    • Author(s)
      Fujii S, Kido A, Baba T, Fujimoto K, Daido S, Matsumura N, Konishi I, Togashi K.
    • Journal Title

      Eur J Radiol

      Volume: 84 Issue: 4 Pages: 581-589

    • DOI

      10.1016/j.ejrad.2015.01.004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] Medical needs for Imaging2017

    • Author(s)
      Kaori Togashi
    • Organizer
      第3回Bordeaux-Kyoto Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Gynecologic MRI: Prognostication, Treatment Planning & Treatment Response2017

    • Author(s)
      Kaori Togashi
    • Organizer
      The 25th International Society for Magnetic Resonance in Medicine (ISMRM2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Functional imaging of the uterus evaluated on cine MR2016

    • Author(s)
      Kaori Togashi
    • Organizer
      The 29th International Congress og Radiology(ICR2016)
    • Place of Presentation
      ブエノスアイレス(アルゼンチン)
    • Year and Date
      2016-09-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Evaluation of uterine function with use of cine MR2016

    • Author(s)
      Kaori Togashi
    • Organizer
      The 29th International Congress og Radiology(ICR2016)
    • Place of Presentation
      ブエノスアイレス(アルゼンチン)
    • Year and Date
      2016-09-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Functional imaging of the uterus evaluated on cine MR2016

    • Author(s)
      Kaori Togashi
    • Organizer
      The 16th Asian-Oceanian Congress of Radiology (AOCR2016)
    • Place of Presentation
      北京(中国)
    • Year and Date
      2016-08-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 子宮肉腫:画像による術前診断は可能か?2015

    • Author(s)
      富樫かおり
    • Organizer
      第55回日本産科婦人科内視鏡学会学術講演会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Functional imaging of the uterus2015

    • Author(s)
      Kaori Togashi
    • Organizer
      The 5th Asian Congress of Abdominal Radiology(ACAR2015)
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Funcional Imaging in Gynecologic Field2015

    • Author(s)
      Kaori Togashi
    • Organizer
      The 15th International Congress of Radiation Research (ICRR2015)
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2015-05-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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