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Standardization of scanning parameters for brain PET and whole-body oncology PET

Research Project

Project/Area Number 15H04914
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionFoundation for Biomedical Research and Innovation

Principal Investigator

Senda Michio  公益財団法人先端医療振興財団, 先端医療センター研究所, 副所長 (00216558)

Co-Investigator(Renkei-kenkyūsha) MATSUMOTO Keiichi  京都医療科学大学, 医療科学部, 講師 (60393344)
ITO Kengo  独立行政法人国立長寿医療研究センター, 放射線診療部, 部長 (70184653)
TERAUCHI Takashi  公益財団法人がん研究会有明病院, 核医学部, 部長 (80392348)
Research Collaborator IKARI Yasuhiko  
AKAMATSU Go  
NISHIDA Hiroyuki  
OHNISHI Akihito  
YAMANE Tomohiko  
IWATSUBO Takeshi  
ODA Keiichi  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2017: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2015: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
KeywordsPET / 標準化 / ファントム / アミロイド
Outline of Final Research Achievements

Quality and quantitative capability of PET images depend on the PET camera model and the scanning methods and parameters. With regard to the brain FDG and amyloid imaging and the whole-body oncology FDG-PET, we have determined phantom test procedures and phantom image criteria that would allow determination of PET scanning parameters and acquisition of PET images of sufficient quality for patient diagnosis. This was applied to multi-center PET studies and provided qualified and harmonized PET images from the participating PET imaging sites. These phantom procedures and criteria were adopted by the Japanese Society of Nuclear Medicine (JSNM) as the standardized PET scanning protocol and as the criteria for the JSNM PET imaging site qualification program, which was used by other PET centers for various projects.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (9 results)

All 2017 2016 2015

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (4 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Inter-rater variability of visual interpretation and comparison with quantitative evaluation of 11C-PiB PET amyloid images of the Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI) multicenter study2017

    • Author(s)
      Yamane T, Ishii K, Sakata M, Ikari Y, Nishio T, Ishii K, Kato T, Ito K, Senda M, J-ADNI Study Group
    • Journal Title

      Eur J Nucl Med Mol Imaging

      Volume: 44 Issue: 5 Pages: 850-857

    • DOI

      10.1007/s00259-016-3591-2

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 認知症を対象としたアミロイドPET における撮像技術と画像解析2017

    • Author(s)
      赤松剛 大西章仁 相田一樹 井狩彌彦 山本泰司 千田道雄
    • Journal Title

      日本放射線技術学会雑誌

      Volume: 73 Pages: 298-308

    • NAID

      130007324382

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phantom criteria for qualification of brain FDG and amyloid PET across different cameras.2016

    • Author(s)
      Ikari Y, Akamatsu G, Nishio T, Ishii K, Ito K, Iwatsubo T, Senda M
    • Journal Title

      EJNMMI Physics

      Volume: 3 Issue: 1 Pages: 23-23

    • DOI

      10.1186/s40658-016-0159-y

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Optimization of image reconstruction conditions with phantoms for brain FDG and amyloid PET imaging.2016

    • Author(s)
      21.Akamatsu G, Ikari Y, Nishio T, Nishida H, Ohnishi A, Aita K, Sasaki M, Sasaki M, Senda M.
    • Journal Title

      Ann Nucl Med

      Volume: 30 Issue: 1 Pages: 18-28

    • DOI

      10.1007/s12149-015-1024-0

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Harmonization of Standardized Uptake Value among Different Generation PET/ CT Cameras Based on a Phantom Experiment —Utility of SUVpeak—2015

    • Author(s)
      19.赤松剛 西田広之 藤野晃 大西章仁 井狩彌彦 西尾知之 前畠彬 佐々木雅之 千田道雄
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 71 Issue: 9 Pages: 735-745

    • DOI

      10.6009/jjrt.2015_JSRT_71.9.735

    • NAID

      130005098984

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] The JSNM strategies for standardization and harmonization of quantitative whole-body FDG-PET studies2017

    • Author(s)
      Akamatsu G, Matsumoto K, Suzuki K, Shimada N, Oda K, Senda M
    • Organizer
      The 57th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] QIBA FDG-PET/CT profileが求める腫瘍SUV repeatabilityのファントム評価2017

    • Author(s)
      赤松剛,西田広之,井狩彌彦,松本圭一,千田道雄
    • Organizer
      第57回日本核医学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Phantom test procedures and criteria for standardization of brain PET imaging across different cameras2017

    • Author(s)
      Akamatsu G, Ikari Y, Wakizaka H, Yamaya T, Kimura Y, Oda K, Senda M
    • Organizer
      2017 IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Phantom Criteria and a site qualification program for standardization of brain PET imaging.2016

    • Author(s)
      Senda M
    • Organizer
      EANM’16 Congress
    • Place of Presentation
      Barcelona
    • Year and Date
      2016-10-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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