londitudinal study for locomotive function for community living elderly peoples and improvement of motor function

• Project/Area Number: 15H04954
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: Kansai University of Welfare Sciences (2016-2017); Nagoya University (2015)
• Principal Investigator: Hasegawa Yukiharu 関西福祉科学大学, 保健医療学部, 教授 (50208500)
• Co-Investigator(Kenkyū-buntansha): 今釜 史郎 名古屋大学, 医学部附属病院, 講師 (40467288) ; 酒井 忠博 名古屋大学, 医学系研究科, 准教授 (60378198) ; 八田 武志 関西福祉科学大学, 健康福祉学部, 教授 (80030469)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000); Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2015: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
• Keywords: 高齢者運動器障害 / 変形性膝関節症 / 運動機能評価 / ロコモ症候群 / 認知機能 / 地域住民検診 / 高齢者運動プログラム / 人工知能 / 長期縦断研究 / 変形性関節症 / 変形性脊椎症 / Ｔｉｍｅ Ｕｐ Ｇｏ ｔｅｓｔ / 認知機能評価 / 高次脳機能評価 / 高齢者住民検診 / 縦断研究 / 運動介入方法 / 認知症 / 骨粗鬆症 / ロコモーティブ症候群 / 一般住民検診 / QOL / 運動向上プログラム

Outline of Final Research Achievements

The purpose of this study is to identify the locomotive syndrome in the community living elderly peoples.
Londitudinallocomotive function was investigated in the community living elderly peoples in Yakumo town. And programs for improveing motor function were also investigated. Healthy volunteers, 244 peoples (male:116, female:128) were included in this study. Average age were 64.8 years old. A 10m walking speed, Time uo and go test (TUG), standing up from 40cm height, and two-step test were examined. TUG and two step test were signifivcantlly corretated. Locomo 25 questionaire were weakly correlated with TUG. TUG and 40cm standing up test were signifivcantlly corretated. The program for the people with locomotive syndrome should walk fast with a longer steps.
In conclusion, TUG is an excellent functional test to identify the locomotive syndrome for the community living elderly peopeles.

Research Products

• [Int'l Joint Research] ルンド大学医学部整形外科(スウェーデン)
• [Int'l Joint Research] Lund University(Sweden)
• [Journal Article] Serum cystatin C level is associated with locomotive syndrome risk and can be an early predictor in community-living people: The Yakumo study (2018)
  • Author(s): Tanaka Satoshi、Ando Kei、Kobayashi Kazuyoshi、Hida Tetsuro、Ito Kenyu、Tsushima Mikito、Morozumi Masayoshi、Machino Masaaki、Ota Kyotaro、Seki Taisuke、Suzuki Koji、Nishida Yoshihiro、Ishiguro Naoki、Hasegawa Yukiharu、Imagama Shiro
  • Journal Title: Modern Rheumatology Volume: なし Issue: 6 Pages: 1-6
  • DOI: 10.1080/14397595.2018.1441675
  • NAID: 120006623830
  • Peer Reviewed
• [Journal Article] Patient-reported outcomes in patients who undergo total hip arthroplasty after periacetabular osteotomy. (2018)
  • Author(s): Osawa Y, Hasegawa Y, Seki T, Takegami Y, Amano T, Ishiguro N
  • Journal Title: J Orthop Sci. Volume: 23 Issue: 2 Pages: 346-349
  • DOI: 10.1016/j.jos.2017.11.001
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head (2017)
  • Author(s): Sakamoto Y, Yamamoto T, Sugano N, Takahashi D, Watanabe T, Atsumi T, Nakamura J, Hasegawa Y, Akashi K, Narita I, Miyamoto T, Takeuchi T, Ikari K, Amano K, Fujie A, Kubo T, Tada Y, Kaneuji A, Nakamura H, Miyamura T, Kabata T, Yamaji K, Okawa T, Sudo A, Ohzono K, Tanaka Y, Yasunaga Y, Matsuda S, Imai Y
  • Journal Title: Sci Rep. Volume: 7 Issue: 1 Pages: 15035-15035
  • DOI: 10.1038/s41598-017-14778-y
  • NAID: 120006817606
  • Peer Reviewed / Open Access
• [Journal Article] Staged decrease of physical ability on the locomotive syndrome risk test is related to neuropathic pain, nociceptive pain, shoulder complaints, and quality of life in middle-aged and elderly people ? The utility of the locomotive syndrome risk test (2017)
  • Author(s): Imagama Shiro、Hasegawa Yukiharu、Ando Kei、Kobayashi Kazuyoshi、Hida Tetsuro、Ito Kenyu、Tsushima Mikito、Nishida Yoshihiro、Ishiguro Naoki
  • Journal Title: Modern Rheumatology Volume: 27 Issue: 6 Pages: 1051-1056
  • DOI: 10.1080/14397595.2017.1285856
  • Peer Reviewed
• [Journal Article] The impact of musculoskeletal diseases on mortality?comparison with internal diseases: A 15-year longitudinal study (2017)
  • Author(s): Kasai Takehiro、Hasegawa Yukiharu、Imagama Shiro、Sakai Tadahiro、Wakai Kenji、Suzuki Koji、Ishiguro Naoki
  • Journal Title: Journal of Orthopaedic Science Volume: 22 Issue: 6 Pages: 1126-1131
  • DOI: 10.1016/j.jos.2017.06.014
  • Peer Reviewed
• [Journal Article] Sarcopenia and physical function are associated with inflammation and arteriosclerosis in community-dwelling people: The Yakumo study (2017)
  • Author(s): Hida Tetsuro、Imagama Shiro、Ando Kei、Kobayashi Kazuyoshi、Muramoto Akio、Ito Kenyu、Ishikawa Yoshimoto、Tsushima Mikito、Nishida Yoshihiro、Ishiguro Naoki、Hasegawa Yukiharu
  • Journal Title: Modern Rheumatology Volume: 28 Issue: 2 Pages: 345-350
  • DOI: 10.1080/14397595.2017.1349058
  • Peer Reviewed
• [Journal Article] Associations among pain catastrophizing, muscle strength, and physical performance after total knee and hip arthroplasty. (2017)
  • Author(s): Hayashi K, Kako M, Suzuki K, Hattori K, Fukuyasu S, Sato K, Kadono I, Sakai T, Hasegawa Y, Nishida Y.
  • Journal Title: World J Orthop. Volume: 8 Issue: 4 Pages: 336-341
  • DOI: 10.5312/wjo.v8.i4.336
  • Peer Reviewed
• [Journal Article] Muscle Damage After Total Hip Arthroplasty Through the Direct Anterior Approach for Developmental Dysplasia of the Hip. (2017)
  • Author(s): Kawasaki M, Hasegawa Y, Okura T, Ochiai S, Fujibayashi T.
  • Journal Title: J Arthroplasty. 2017 Aug;32(8):2466-2473. Volume: 32 Issue: 8 Pages: 2466-2473
  • DOI: 10.1016/j.arth.2017.03.043
  • Peer Reviewed
• [Journal Article] Incidence of Ceramic Liner Malseating After Ceramic-on-Ceramic Total Hip Arthroplasty Associated With Osteolysis: A 5- to 15-Year Follow-Up Study. (2017)
  • Author(s): Higuchi Y, Hasegawa Y, Komatsu D, Seki T, Ishiguro N.
  • Journal Title: J Arthroplasty. Volume: 32 Issue: 5 Pages: 1641-1646
  • DOI: 10.1016/j.arth.2016.11.044
  • Peer Reviewed
• [Journal Article] Absence of a relationship between joint space narrowing and osteophyte formation in early knee osteoarthritis among Japanese community-dwelling elderly individuals: A cross-sectional study (2017)
  • Author(s): Komatsu Daigo、Hasegawa Yukiharu、Kojima Toshihisa、Seki Taisuke、Higuchi Yoshitoshi、Ishiguro Naoki
  • Journal Title: Modern Rheumatology Volume: 27 Issue: 4 Pages: 675-682
  • DOI: 10.1080/14397595.2016.1232775
  • Peer Reviewed
• [Journal Article] Total Hip Arthroplasty After Periacetabular and Intertrochanteric Valgus Osteotomy. (2017)
  • Author(s): Osawa Y, Hasegawa Y, Okura T, Morita D, Ishiguro N.
  • Journal Title: J Arthroplasty. Volume: 32 Issue: 3 Pages: 857-861
  • DOI: 10.1016/j.arth.2016.08.023
  • Peer Reviewed
• [Journal Article] Survivorship Between 2 Different Ceramic-on-Ceramic Total Hip Arthroplasty With or Without a Metal-Backed Titanium Sleeve Bearing: A 5- to 14-Year Follow-Up Study. (2017)
  • Author(s): Higuchi Y, Hasegawa Y, Komatsu D, Seki T, Ishiguro N.
  • Journal Title: J Arthroplasty. 2017 Jan;32(1):155-160. Volume: 32 Issue: 1 Pages: 155-160
  • DOI: 10.1016/j.arth.2016.06.014
  • Peer Reviewed
• [Journal Article] Laterality of radiographic osteoarthritis of the knee (2017)
  • Author(s): Komatsu Daigo、Ikeuchi Kazuma、Kojima Toshihisa、Takegami Yasuhiko、Amano Takafumi、Tsuboi Masaki、Ishiguro Naoki、Hasegawa Yukiharu
  • Journal Title: Laterality: Asymmetries of Body, Brain and Cognition Volume: 22 Issue: 3 Pages: 340-353
  • DOI: 10.1080/1357650x.2016.1199560
  • Peer Reviewed
• [Journal Article] Gait speeda associated with anxiety responses to pain in osteoarthritic patients (2016)
  • Author(s): 1.Hayashi Kazuhiro, Kako Masato, Suzuki Kentaro, Hattori Keiko, Fukuyasu Saori, Sato Koji, Kadona Izumi, Sakai Tadahiro, Yukiharu Hasegawa, Nishida Yoshihiro
  • Journal Title: Pain Medine 17(3), 606-613, 2016. http://dx. Volume: 17 Pages: 606-6013
  • DOI: 10.1111/pme.12897
  • Peer Reviewed
• [Journal Article] Absence of a relationship between joint space narrowing and osteophyte formation in early knee osteoarthritis among Japanese community-dwelling elderly individuals: A cross-sectional study. (2016)
  • Author(s): 3.Komatsu D, Hasegawa Y, Kojima T, Seki T, Higuchi Y, Ishiguro N.
  • Journal Title: Mod Rheumatol. 2016 Oct 14:1-8. Volume: 14 Pages: 1-8
  • Peer Reviewed
• [Journal Article] Validity of a tablet computer version of the Japanese Orthopaedic Association hip disease evaluation questionnaire: a pilot study. (2016)
  • Author(s): 5.Takegami Y, Seki T, Kaneuji A, Nakao A, Hasegawa Y, Ishiguro N.
  • Journal Title: Nagoya J Med Sci. 2016 Aug;78(3):237-44 Volume: 78 Pages: 237-244
  • Peer Reviewed
• [Journal Article] Laterality of radiographic osteoarthritis of the knee. (2016)
  • Author(s): 8.Komatsu D, Ikeuchi K, Kojima T, Takegami Y, Amano T, Tsuboi M, Ishiguro N, Hasegawa Y
  • Journal Title: Laterality of radiographic osteoarthritis of the knee. Volume: 27 Pages: 1-14
  • Peer Reviewed
• [Journal Article] Spinal sagittal balance substantially influences locomotive syndrome and physical performance in community-living middle-aged and elderly women. (2016)
  • Author(s): 13.Muramoto A, Imagama S, Ito Z, Hirano K, Ishiguro N, Hasegawa Y.
  • Journal Title: J Orthop Sci.21(2):216-21 Volume: 21 Issue: 2 Pages: 216-221
  • DOI: 10.1016/j.jos.2015.12.016
  • Peer Reviewed
• [Journal Article] Validity of radiographic assessment of the knee joint space using automatic image analysis. (2016)
  • Author(s): 15.Komatsu D, Hasegawa Y, Kojima T, Seki T, Ikeuchi K, Takegami Y, Amano T, Higuchi Y, Kasai T, Ishiguro N.
  • Journal Title: Mod Rheumatol Volume: 26 Issue: 5 Pages: 761-777
  • DOI: 10.3109/14397595.2015.1130679
  • Peer Reviewed
• [Journal Article] Surgical skills training for primary total hip arhtroplasty. (2015)
  • Author(s): Yukiharu Hasegawa, Takahumi Amano
  • Journal Title: Nagoya J Med Sci Volume: 77 Pages: 1-7
  • Peer Reviewed / Open Access
• [Journal Article] Surgical Techniques for Eccentric Rotational Acetabular osteotomy. Supplumentum (2015)
  • Author(s): Yukiharu Hasegawa, Takahumi Amano
  • Journal Title: J Bone Joint Surg Am Volume: 97 Pages: 1-10
  • Peer Reviewed / Open Access
• [Presentation] 一般住民検診における中高齢者の転倒危険因子―フレイル（frailty）の関連 (2017)
  • Author(s): 今釜史郎、長谷川幸治、飛田哲郎、関泰輔、安藤圭、小林和克、伊藤研悠、都島幹人、西田佳弘、石黒直樹
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 術後早期全荷重した寛骨臼骨切り術は成績不良である (2017)
  • Author(s): 長谷川幸治、小松大悟
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] ロコモ度テストは抑うつも反映する (2017)
  • Author(s): 今釜史郎、長谷川幸治、安藤圭、関泰輔、小林和克、飛田哲郎、伊藤研悠、都島幹人、西田佳弘、石黒直樹
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 一般地域住民における認知機能に運動機能は有意に関連する (2017)
  • Author(s): 長谷川幸治、今釜史郎、酒井忠博、八田武志
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 4年間の骨密度変化に影響する抗酸化栄養素血性地と側品接種頻度の縦断的研究 (2017)
  • Author(s): 関泰輔、今釜史郎、竹上靖彦、小松大悟、樋口善俊、笠井健広、大澤郁介、石黒直樹、長谷川幸治
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 地域住民における立位アライメント変化―10年の縦断研究ー (2017)
  • Author(s): 伊藤研悠、今釜史郎、安藤圭、飛田哲郎、都島幹人、松本明之、両角正義、西田佳弘、石黒直樹、長谷川幸治
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 一般住民における中高年者の抑うつと痛みの関連―Yakumo study- (2017)
  • Author(s): 今釜史郎、長谷川幸治、安藤圭、関泰輔、小林和克、飛田哲郎、伊藤研悠、都島幹人、西田佳弘、石黒直樹
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 脊椎アライメント不良および脊椎可動域低下は頸部痛、腰痛と関連する (2017)
  • Author(s): 鈴木健太郎、今釜史郎、安藤圭、小林和克、関泰輔、伊藤研悠、都島幹人、松山実乃里、西田佳弘、石黒直樹、長谷川幸治
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] ロコモ度テストは抑うつも反映する (2017)
  • Author(s): 今釜史郎、長谷川幸治、関泰輔、安藤圭、小林和克、都島幹人、笠井健広、飛田哲郎、伊藤研悠、西田佳弘、石黒直樹
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 10年間で膝Ｘ線はどれだけ変化するか -膝痛出現の有無による比較― (2017)
  • Author(s): 小松大悟、関泰輔、今釜史郎、竹上靖彦、笠井健広、樋口善俊、大澤郁介、草野大樹、石黒直樹、長谷川幸治
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] ＪＯＡＣＭＥＱと頸椎アライメントの関連 (2017)
  • Author(s): 安藤圭、今釜史郎、小林和克、飛田哲郎、伊藤研悠、都島幹人、西田佳弘、長谷川幸治、石黒直樹
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 股関節可動域は女性が有意に大きく左右差も存在し、日整会参考値との誤差を認める (2017)
  • Author(s): 草野大樹、関泰輔、今釜史郎、竹上靖彦、笠井健広、小松大悟、樋口善俊、大澤郁介、西田佳弘、石黒直樹、長谷川幸治
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 地域住民における運動器疾患の長期縦断的研究と運動機能向上プログラムの開発 (2016)
  • Author(s): 長谷川幸治
  • Organizer: 中部整形外科災害外科学会2016年4月9日
  • Place of Presentation: 浜松市
  • Invited
• [Presentation] 一般住民において1年後の腰痛の改善は予測できるか (2015)
  • Author(s): 伊藤全哉、長谷川幸治、今釜史郎、村本明生，飛田哲郎、伊藤研悠、石川喜資、石黒直樹
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 骨粗鬆症は15年後の生命予後を1.8倍悪化させる (2015)
  • Author(s): 樋口善俊、坪井真幸、笠井健広、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 一般住民の店頭に対するサルコぺニアと脊椎アライメントの影響 (2015)
  • Author(s): 今釜史郎、長谷川幸治、飛田哲朗、村本明生、伊藤研悠、石川喜資、石黒直樹
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] サルコぺニアと慢性炎症 ―高感度CRP高値は筋量低下と運動機能低下に関連す (2015)
  • Author(s): 飛田哲朗、今釜史郎、村本明生、伊藤研悠、石川喜資、石黒直樹、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] サルコぺニアは逆流性食道炎と関連があるか －筋量と筋力の検討 (2015)
  • Author(s): 今釜史郎、長谷川幸治、飛田哲朗、村本明生、伊藤研悠、石川喜資、石黒直樹
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 一般住民における抗酸化栄養素とロコモーティブシンドロームの検討 (2015)
  • Author(s): 関泰輔、池内一磨、竹上靖彦、天野貴文、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] サルコぺニア（加齢性筋量減少症）は神経障害性疼痛の危険因子である (2015)
  • Author(s): 今釜史郎、長谷川幸治、飛田哲朗、村本明生、伊藤研悠、石川喜資、石黒直樹
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 一般住民における変形性膝関節症は15年後の死亡率を2.2倍高くする (2015)
  • Author(s): 笠井健広、池内一磨、石黒直樹、坪井真幸、浜田恭、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 神経障害性疼痛がロコモーティブシンドロームおよび運動機能に及ぼす影響 (2015)
  • Author(s): 村本明生、今釜史郎、飛田哲郎、伊藤研悠、石川喜資、石黒直樹、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21
• [Presentation] 地域住民健診における腰部脊柱管狭窄症と排尿障害の合併について (2015)
  • Author(s): 石川喜資、今釜史郎、伊藤全哉、村本明生、飛田哲郎、伊藤研悠、本城久司、石黒直樹、長谷川幸治
  • Organizer: 第88回日本整形外科学会
  • Place of Presentation: 神戸
  • Year and Date: 2015-05-21