| Project/Area Number |
15H05260
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Veterinary medical science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
OGAWA HARUKO 帯広畜産大学, 畜産学部, 教授 (10400079)
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| Co-Investigator(Kenkyū-buntansha) |
水谷 哲也 東京農工大学, 農学部, 教授 (70281681)
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| Co-Investigator(Renkei-kenkyūsha) |
IMAI KUNITOSHI 帯広畜産大学, 動物・食品検査診断センター, 教授 (70374767)
OHMATSU TSUTOMU 東京農工大学, 農学部, 講師 (60455392)
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| Research Collaborator |
Runstadler Jonathan マサチューセッツ工科大学, 准教授
Vuong Bui Nghia ベトナム国立獣医学研究所, ウイルス学研究部, 門長
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2017: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Keywords | ウイルス / 感染症 / 疫学 / 進化 / 家禽 / 鳥インフルエンザ / ニューカッスル病 / 鳥インフルエンザウイルス / ニューカッスル病ウイルス / 海外 / ウィルス / 獣医学 |
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| Outline of Final Research Achievements |
International collaborative studies were performed on the epidemiological surveillance of the highly pathogenic avian influenza virus (HPAIV) and Newcastle disease virus (NDV) in Vietnam, Egypt, and Kyrgyz. Virological and genetical analyses were conducted on the isolated viruses, and the viral origin and evolution, and viral pathogenicity were further analyzed. Monoclonal antibodies reacting with various genotypes of H5 HPAIV were produced, which may be utilized in the diagnosis of HPAIV. The NDV strains obtained in Egypt and Kyrgyz were genetically distinct from the vaccine strains, suggesting a possible reduction in vaccine efficacy.
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