Digitization, Histological Analyses and Making Web Atlas of Blechschmidt Collection
| Project/Area Number |
15H05270
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
General anatomy (including histology/embryology)
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
高桑 徹也 京都大学, 医学研究科, 教授 (40244933)
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| Research Collaborator |
Viebahn Christoph ゲッティンゲン大学, 医学部, 教授
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
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| Keywords | Human Embryo / Blechschmidt Collection / digitization / flatbed scanner / digitize / 3D reconstrcution / sliced specimen / 解剖学 / 発生学 |
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| Outline of Final Research Achievements |
Regenerative medicine is now developing, and it is important to understand the mechanism of human development. Sets of serial sections of embryos and fetuses are the largest source of information, but it is difficult to acquire human embryo specimens newly. Therefore, preservation and utilization of existing specimens are required. The Blechschmidt collection (Germany) is one of various collection including many sets of serial histological sections, however, glass slides of histological specimens normally deteriorate over time and staining by hematoxylin and eosin (HE), typically fade. Now we saved this important samples by digitization for research use. Three-dimensional reconstruction was attempted from the obtained two-dimensional image. In addition, we arranged the images and publishing them on the web, thereby contributing to the further activation of research.
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Report
(4 results)
Research Products
(111 results)
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[Journal Article] Merging and fractionation of muscle synergy indicate the recovery process in patients with hemiplegia: the first study of patients after subacute stroke.2016
Author(s)
Hashiguchi Y, Ohata K, Kitatani R, Yamakami N, Sakuma K, Osako S, Aga Y, Watanabe A, Yamada S.
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Journal Title
Neural Plasticity,
Volume: 2,016
Pages: 5282957-5282957
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Nationwide survey for current clinical status of amniocentesis and maternal serum marker test in Japan.2016
Author(s)
Miyake H, Yamada S, Fujii Y, Sawai H, Arimori N, Yamanouchi Y, Ozasa Y, Kanai M, Sago H, Sekizawa A, Takada F, Masuzaki H, Matsubara Y, Hirahara F, Kugu K.
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Journal Title
J Hum Gen
Volume: 61(10)
Issue: 10
Pages: 879-884
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Presentation] 「The first human embryonic research for the development of the nasal septum using geometric morphometrics: A new insight for the sensitive period for the Binder phenotype.」(Poster) Cleft20172017
Author(s)
Katsube M, Yamada S, Uwabe C, Makishima H, Miyazaki R, Yamaguchi Y, Ishiyama H, Yamamoto A, Morimoto N, Ito T, Imai H, Matsuda T, Suzuki S.
Organizer
INTERNATIONAL CLEFT CONGRESS 2017
Place of Presentation
Radisson Blu Resort, Temple Bay, Mahabalipuram（Chennai, India）
Year and Date
2017-02-08
Related Report
Int'l Joint Research
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[Presentation] ヒト発生学と先天異常2016
Author(s)
山田重人
Organizer
第12回北関東遺伝診療フォーラム
Place of Presentation
大宮パレスホテル 埼玉県大宮市
Year and Date
2016-11-28
Related Report
Invited
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[Presentation] Current Status of Social Issues for People with Down Syndrome in Japan: From Nationwide Survey.2016
Author(s)
Miyake H, Yamada S, Fujii Y, Taniguchi-Ikeda M, Urano M, Ozasa Y, Kanai M, Fukushima A, Matsubara Y, Saito K, Konishi I.
Organizer
The 13th International Congress of Human Genetics.
Place of Presentation
Kyoto International Conterrence Center,Japan (sakyo-ku kyoto)
Year and Date
2016-04-03
Related Report
Int'l Joint Research
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[Presentation] Characteristics of the Genetic Counseling in Kyoto University Hospital to Figure Out the Genetic Counseling Needs in Japan.2016
Author(s)
Matsukawa M, Nishio H, Hiraoka Y, Honda S, Inaba A, Takamine E, Yonei A, Torishima M, Murakami H, Kitajiri S, Wada T, Miyake H, Yamada S, Heike T, Kosugi S.
Organizer
The 13th International Congress of Human Genetics.
Place of Presentation
Kyoto International Conterrence Center,Japan (sakyo-ku kyoto)
Year and Date
2016-04-03
Related Report
Int'l Joint Research
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[Presentation] The current status of conventional prenatal diagnosis in Japan: A Nationwide survey of obstetrics/gynecology facilities.2015
Author(s)
Miyake H, Yamada S, Fujii Y, Sawai H, Arimori N, Yamanuchi Y, Ozasa Y, Kanai M, Sago H, Sekizasa A, Takada F, Masuzaki H, Matsubara Y, Hirahara F, Kugu K
Organizer
21st The International Federation of Gynecology and Obstetrics (FIGO)
Place of Presentation
Vancouver, Canada
Year and Date
2015-10-04
Related Report
Int'l Joint Research
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[Presentation] ヒト発生学と発生学研究2015
Author(s)
山田重人
Organizer
第25回遺伝医学セミナー
Place of Presentation
三井ガーデンホテル 千葉県千葉市 中央区
Year and Date
2015-09-04
Related Report
Invited
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[Presentation] Survey of conventional prenatal diagnosis in Japan - Nationwide study for obstetricians about prenatal diagnosis2015
Author(s)
Miyake H, Yamada S, Fujii Y, Sawai H, Arimori N, Yamanuchi Y, Ozasa Y, Kanai M, Sago H, Sekizasa A, Takada F, Masuzaki H, Matsubara Y, Hirahara F, Kugu K
Organizer
ISPD 19th International Conference on Prenatal Diagnosis and Therapy
Place of Presentation
Washington, District of Columbia, United States
Year and Date
2015-07-12
Related Report
Int'l Joint Research
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