| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2018: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
|
|---|
| Outline of Final Research Achievements |
In MRSA isolates in Japan, strains carrying psm-mec gene mutations produce higher amounts of toxins than those carrying intact psm-mec gene. However, it is not known whether this theory is applicable to other MRSA strains having different genetic backgrounds from the MRSA isolates in Japan. In this study, we isolated MRSA strains from north and center regions of Thailand and revealed that strains carrying psm-mec mutations produce higher amounts of toxins than those carrying intact psm-mec. In addition, the MRSA isolates in Thailand had different genetic backgrounds from the MRSA isolates in Japan. These results suggest that psm-mec mutations cause high toxin production in MRSA isolates having various genetic backgrounds.
|
