Integration of Polymer Nanosheet and Bioelectronics for the Development of Bio-Monitoring and Controlling Technology
| Project/Area Number |
15H05355
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Waseda University |
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Principal Investigator |
Fujie Toshinori 早稲田大学, 高等研究所, 准教授(任期付) (70538735)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥23,660,000 (Direct Cost: ¥18,200,000、Indirect Cost: ¥5,460,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2015: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
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| Keywords | 高分子ナノシート / プリンテッドエレクトロニクス / エラストマー / 導電性高分子 / ナノインク / 脂肪組織由来幹細胞 / 細胞移植 / バイオイメージング / 高分子ナノ薄膜 / PEDOT:PSS / バイオロボティクス / 生体材料学 / 高分子化学 / バイオエレクトロニクス / 生体計測 / 細胞組織工学 / 高分子超薄膜 / ナノバイオ材料 / フレキシブルエレクトロニクス / ウェアラブルデバイス / 組織工学 / 再生医工学 / ナノバイオ / 生体材料 / マイクロ・ナノデバイス / 超薄膜 / 再生医学 |
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| Outline of Final Research Achievements |
In this study, the printed nanofilm was constructed through integration of printing technology and molecular assembly into the preparation of free-standing polymer nanosheets. Introduction of conductive polymers or nanoinks to the building blocks of nanosheets realized skin-contact electrodes and electronics. Then, phase separation led to preparation of porous nanosheets, allowing for permeation of several substances from molecules to cells, on which stem cells were cultured in the application of cell delivery. Furthermore, nanosheet-based thermosensor embedded with thermo-sensitive dyes realized real-time imaging of thermogenesis on the muscle tissue from cells to tissues.
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Report
(4 results)
Research Products
(86 results)
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[Journal Article] Interfacial effects on the crystallization and surface properties of poly(L-lactic acid) ultrathin films2016
Author(s)
Udagawa, A., Fujie, T., Kawamoto, Y., Saito, A., Takeoka, S., Asahi, T.
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Journal Title
Polymer J.
Volume: 48
Issue: 2
Pages: 157-161
DOI
NAID
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Roll to roll processing of ultraconformable conducting polymer nanosheets2015
Author(s)
Zucca, A., Yamagishi, K., Fujie, T., Takeoka, S., Mattoli, V., Greco, F.
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Journal Title
J. Mater. Chem. C
Volume: 3
Issue: 25
Pages: 6539-6548
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Stem cell differentiation toward the myogenic lineage for muscle tissue regeneration: A focus on muscular dystrophy2015
Author(s)
Ostrovidov, S., Shi, X., Sadeghian, R.B., Salehi, S., Fujie, T., Bae, H., Ramalingam, M., Khademhosseini, A.
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Journal Title
Stem Cell Rev.
Volume: 11
Issue: 6
Pages: 866-884
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] Temperature Mapping of Living Tissues Using Ultra-Conformable Polymer Nanosheets Loading Thermo-Sensitive Dyes2017
Author(s)
Fujie, T., Miyagawa, T., Ferdinandus, Vo Doan, T. T., Sato, H., Takeoka, S.
Organizer
2017 MRS Fall Meetings & Exhibit
Related Report
Int'l Joint Research
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[Presentation] Thermo-sensitive dye laden polymer nanosheets for ratiometric temperature mapping of living muscle tissues2017
Author(s)
Fujie, T., Miyagawa, T., Ferdinandus, Vo Doan, T. T., Sato, H., Takeoka, S.
Organizer
254th ACS National Meeting & Exposition
Related Report
Int'l Joint Research
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[Presentation] Conductive Polymer Nanosheets for Ultra-Conformable Bioelectrodes2016
Author(s)
Fujie, T., Yamagishi, K., Zucca, A., Takeoka, S., Mattoli, V., Greco, F.
Organizer
Asia Nano 2016
Related Report
Int'l Joint Research
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[Presentation] Roll-to-roll fabrication of conductive polymer nanosheets for the development of ultraconformable skin-contact electrodes2016
Author(s)
Fujie, T., Zucca, A., Yamagishi, K., Takeoka, S., Mattoli, V., Greco, F
Organizer
World Biomaterials Congress 2016
Related Report
Int'l Joint Research
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[Book] Conductive Nanosheets for Ultra-Conformable Smart Electronics (ch. 11), in Flexible and Stretchable Medical Devices (eds Takei, K.)2018
Author(s)
Yamagishi, K., Taccola, S., Takeoka, S., Fujie, T., Mattoli, V., Greco, F.
Total Pages
33
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
ISBN
9783527804856
Related Report
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