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Effects of robot training and noninvasive brain stimulation on the motor and cognitive functions of stroke patients

Research Project

Project/Area Number 15H05359
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Rehabilitation science/Welfare engineering
Research InstitutionFujita Health University

Principal Investigator

Takeda Kotaro  藤田医科大学, 保健学研究科, 准教授 (50618733)

Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥23,920,000 (Direct Cost: ¥18,400,000、Indirect Cost: ¥5,520,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Keywordsロボット / リハビリテーション / ロボットリハビリテーション / 感覚障害 / ロボット・リハビリテーション / fNIRS / 電気刺激 / 脳・神経 / 医療・福祉
Outline of Final Research Achievements

We constructed evidence about robot rehabilitation and brain stimulation in stroke rehabilitation. (1) Neuromuscular electrical stimulation during robotic training might facilitate the activation of paretic muscles, resulting in paralysis improvement. (2) Sensory impairment was one of the factors that reduced the effect of robot rehabilitation. (3) Anodal transcranial direct current stimulation over the left temporoparietal area improved audioverbal memory performance after stroke. (4) In addition, retrospective studies showed that damage to the posterior limb of the internal capsule and cognitive function evaluation using the Raven's Colored Progressive Matrices test might be useful for predicting the outcome of motor paralysis and activities of daily living in patients with putaminal hemorrhage.

Academic Significance and Societal Importance of the Research Achievements

脳卒中後には運動機能や認知機能などさまざまな障害が残り,これらの障害を改善することがリハビリテーションの目的のひとつである.近年,ロボット訓練や非侵襲電気刺激といった新しいリハビリ法が数多く提案されているが,エビデンスが不足しているのが問題のひとつであった.そこで本研究では,電気刺激と上肢訓練ロボットの併用効果や,麻痺改善を阻害し得る感覚障害がロボット訓練効果へ与える影響を明らかにすることで,より臨床場面に即した状況における応用に関するエビデンスを提供するに至った.

Report

(5 results)
  • 2019 Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (10 results)

All 2020 2019 2018 2017 2016 2015

All Journal Article (6 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 6 results,  Open Access: 4 results,  Acknowledgement Compliant: 3 results) Presentation (4 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] Relationship between Hematoma Volume and Motor Impairment in Putaminal Hemorrhage2020

    • Author(s)
      Ohnishi Hitoshi、Takeda Kotaro、Watanabe Makoto、Maeshima Shinichiro、Sonoda Shigeru
    • Journal Title

      Journal of Stroke and Cerebrovascular Diseases

      Volume: 29 Issue: 6 Pages: 104812-104812

    • DOI

      10.1016/j.jstrokecerebrovasdis.2020.104812

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Sensory Loss on Improvements of Upper-Limb Paralysis Through Robot-Assisted Training: A Preliminary Case Series Study2019

    • Author(s)
      Miyasaka Hiroyuki、Takeda Kotaro、Ohnishi Hitoshi、Orand Abbas、Sonoda Shigeru
    • Journal Title

      Applied Sciences

      Volume: 9 Issue: 18 Pages: 3925-3925

    • DOI

      10.3390/app9183925

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Hemodynamic responses in prefrontal cortex and personality characteristics in patients with bulimic disorders: a near-infrared spectroscopy study.2018

    • Author(s)
      Numata N, Hirano Y, Sutoh C, Matsuzawa D, Takeda K, Setsu R, Shimizu E, Nakazato M.
    • Journal Title

      Eat Weight Disord, in press

      Volume: - Issue: 1 Pages: 1-9

    • DOI

      10.1007/s40519-018-0500-7

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial direct current stimulation improves audioverbal memory in stroke patients2017

    • Author(s)
      Kazuta T, Takeda K, Osu R, Tanaka S, Oishi A, Kondo K, Liu M
    • Journal Title

      Am J Phys Med Rehabil

      Volume: - Issue: 8 Pages: 565-571

    • DOI

      10.1097/phm.0000000000000686

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Ability of electrical stimulation therapy to improve the effectiveness of robotic training for paretic upper limbs in patients with stroke2016

    • Author(s)
      Miyasaka H, Orand A, Ohnishi H, Tanino G, Takeda K, Sonoda S.
    • Journal Title

      Med Eng Phys

      Volume: 38 Issue: 11 Pages: 1172-1175

    • DOI

      10.1016/j.medengphy.2016.07.010

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Reduction of global interference of scalp-hemodynamics in functional near-infrared spectroscopy using short distance probes2016

    • Author(s)
      Sato T, Nambu I, Takeda K, Aihara T, Yamashita O, Isogaya Y, Inoue Y, Otaka Y, Wada Y, Kawato M, Sato MA, Osu R
    • Journal Title

      Neuroimage

      Volume: 141 Pages: 120-132

    • DOI

      10.1016/j.neuroimage.2016.06.054

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Development of a simple device for assessment of spasticity2017

    • Author(s)
      Takeda K, Maeda H, Sonoda S
    • Organizer
      The 47th Annual Meeting of the Society for Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 上肢ロボットのアシスト量からみる麻痺側上肢の重症度別の麻痺回復過程の違い2017

    • Author(s)
      宮坂裕之, 武田湖太郎, 大西斉, Orand A, 園田茂
    • Organizer
      第51回日本作業療法学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 機能的近赤外分光法(fNIRS)の基礎と実践2016

    • Author(s)
      武田湖太郎
    • Organizer
      第23回脳機能とリハビリテーション研究会 学術集会 教育セミナー
    • Place of Presentation
      千葉県立保健医療大学 幕張キャンパス(千葉市美浜区)
    • Year and Date
      2016-04-24
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 機能的近赤外分光法(fNIRS)の原理と実践2015

    • Author(s)
      武田湖太郎
    • Organizer
      第22回脳機能とリハビリテーション研究会 学術集会
    • Place of Presentation
      千葉県立保健医療大学 幕張キャンパス(千葉市美浜区)
    • Year and Date
      2015-04-12
    • Related Report
      2015 Annual Research Report
    • Invited

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Published: 2015-04-16   Modified: 2022-11-04  

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