| Budget Amount *help |
¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
Fiscal Year 2017: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2016: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2015: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
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| Outline of Final Research Achievements |
Sarcopenia is defined as age-related loss of skeletal muscle mass and function. Skeletal muscle, in addition to being comprised of a heterogeneous muscle fiber population, also includes extracellular components that do not contribute to positive tensional force production. Here we test segmental bioelectrical impedance spectroscopy (S-BIS) to assess muscle intracellular mass and composition. S-BIS can evaluate electrical properties that may be related to muscle force production. We found that S-BIS measures was more sensitive than traditional methods. Indices of extracellular (noncontractile) and cellular (contractile) compartments in skeletal muscle tissues were determined using the S-BIS measures. Our finding underscores the value of S-BIS to measure muscle composition and suggests that S-BIS should be highly informative in skeletal muscle physiology.
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