| Budget Amount *help |
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2017: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2016: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2015: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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| Outline of Final Research Achievements |
Skeletal muscle is the largest tissue in the human body and is a highly plastic tissue that readily adapts its contractile and metabolic properties and muscle sizes in response to physical activity. Recent evidence suggests that skeletal muscle produces myokines that play a role in maintaining systemic homeostasis. In this study, we aimed to understand how skeletal muscle influences systemic homeostasis using transgenic mouse lines, and found that Zmynd17, Crym, and Notch proteins expressed in muscle control muscle function and systemic metabolism.
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