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Development of a predicting system for children with ADHD

Research Project

Project/Area Number 15H05405
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Special needs education
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

yasumura akira  国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 知的障害研究部, 研究生 (60723468)

Research Collaborator INAGAKI Masumi  
NAKAGAWA Eiji  
YAMASHITA Yushiro  
AIHARA Masao  
MIYAJIMA Tasuku  
OMORI Mikimasa  
FUKUDA Ayako  
TACHIMORI Hisateru  
YASUMURA Yukiko  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Keywords発達障害 / ADHD / 機械学習 / 抑制機能 / 前頭前野 / 小児 / 診断補助 / バイオマーカー / 脳機能 / 脳機能計測 / 近赤外分光法
Outline of Final Research Achievements

The researchers devised a method to predict the severity of children with attention deficit / hyperactivity disorder (ADHD) among developmental disorders using brain function measurement, and have applied for international patent (US). Then, in order to search for ADHD biomarkers, the diagnostic prediction accuracy was examined by applying machine learning to behavior during inhibition task and frontal cerebral blood flow dynamics. As a result, accuracy of sensitivity 88.7%, specificity 83.8%, area under the receiver operation characteristic curve 0.90 was obtained. It was shown that the evaluation method of restraint task using machine learning has high utility as diagnostic aid for children with ADHD. Research results were published in international scientific journals.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (8 results)

All 2018 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (3 results) (of which Invited: 1 results) Book (1 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] Applied machine learning method to predict children with ADHD using prefrontal cortex activity: A multicenter study in Japan2017

    • Author(s)
      Yasumura Akira、Omori Mikimasa、Fukuda Ayako、Takahashi Junichi、Yasumura Yukiko、Nakagawa Eiji、Koike Toshihide、Yamashita Yushiro、Miyajima Tasuku、Koeda Tatsuya、Aihara Masao、Tachimori Hisateru、Inagaki Masumi
    • Journal Title

      Journal of Attention Disorders

      Volume: pub-online Issue: 14 Pages: 1-9

    • DOI

      10.1177/1087054717740632

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decision Making in Children with Attention-Deficit/Hyperactivity Disorder.2016

    • Author(s)
      Akira Yasumura, Yoshiyuki Takimoto, Eisuke Nakazawa, Masumi Inagaki
    • Journal Title

      Open Journal of Pediatrics

      Volume: 6 Issue: 02 Pages: 158-162

    • DOI

      10.4236/ojped.2016.62023

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Behavioral and Neural Enhancing Effects of a Summer Treatment Program in Children with Attention Deficit Hyperactivity Disorder.2016

    • Author(s)
      Akira Yasumura, Kotaro Yuge, Chiyomi Egami, Chizuru Anai, Akiko Mukasa, Yushiro Yamashita, Masumi Inagaki
    • Journal Title

      Open Journal of Pediatrics

      Volume: 6 Issue: 01 Pages: 91-99

    • DOI

      10.4236/ojped.2016.61015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 「注意」機能をつなぐ-神経心理学から見た視覚的な注意2018

    • Author(s)
      安村 明
    • Organizer
      第29回日本発達心理学会 シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 基礎研究と応用研究の融合2016

    • Author(s)
      安村 明
    • Organizer
      第12回東北心理学会・北海道心理学会合同大会
    • Place of Presentation
      コラッセふくしま
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 近赤外分光法(NIRS)を用いたADHD児における認知機能の発達的変化2015

    • Author(s)
      安村 明、中川栄二、山下裕史朗、宮島祐、小枝達也、相原正男、小池敏英、稲垣真澄
    • Organizer
      第45回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2015-11-06
    • Related Report
      2015 Annual Research Report
  • [Book] ADHD - New Directions in Diagnosis and Treatment.2015

    • Author(s)
      Akira Yasumura and Masumi Inagaki
    • Total Pages
      11
    • Publisher
      InTech
    • Related Report
      2015 Annual Research Report
  • [Patent(Industrial Property Rights)] COGNITIVE FUNCTION TESTING SYSTEM, COGNITIVE FUNCTION ESTIMATION SYSTEM, COGNITIVE FUNCTION TESTING METHOD, AND COGNITIVE FUNCTION ESTIMATION METHOD2015

    • Inventor(s)
      Akira Yasumura, Masumi Inagaki
    • Industrial Property Rights Holder
      Akira Yasumura, Masumi Inagaki
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015
    • Acquisition Date
      2017
    • Related Report
      2017 Annual Research Report
    • Overseas

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Published: 2015-04-16   Modified: 2019-12-27  

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